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4E58
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BU of 4e58 by Molmil
Crystal structure of GCC(LCG)CCGC duplex containing LNA residue
分子名称: RNA duplex containing CCG repeats, SULFATE ION
著者Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, R.
登録日2012-03-14
公開日2012-12-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Crystallographic characterization of CCG repeats.
Nucleic Acids Res., 40, 2012
5HES
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BU of 5hes by Molmil
Human leucine zipper- and sterile alpha motif-containing kinase (ZAK, MLT, HCCS-4, MRK, AZK, MLTK) in complex with vemurafenib
分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase kinase kinase MLT, N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide
著者Mathea, S, Salah, E, Abdul Azeez, K.R, Tallant, C, Szklarz, M, Chaikuad, A, Shrestha, B, Sorrell, F.J, Elkins, J.M, Shrestha, L, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
登録日2016-01-06
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.
Acs Chem.Biol., 11, 2016
7R0J
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BU of 7r0j by Molmil
Structure of the V2 receptor Cter-arrestin2-ScFv30 complex
分子名称: Arrestin2, ScFv30, V2R Cter
著者Bous, J, Fouillen, A, Trapani, S, Granier, S, Mouillac, B, Bron, P.
登録日2022-02-02
公開日2022-09-14
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex.
Sci Adv, 8, 2022
7R0C
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BU of 7r0c by Molmil
Structure of the AVP-V2R-arrestin2-ScFv30 complex
分子名称: AVP, Arrestin2, ScFv30, ...
著者Bous, J, Fouillen, A, Trapani, S, Granier, S, Mouillac, B, Bron, P.
登録日2022-02-01
公開日2022-09-14
実験手法ELECTRON MICROSCOPY (4.73 Å)
主引用文献Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex.
Sci Adv, 8, 2022
6FE0
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BU of 6fe0 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide.
分子名称: 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, Carbonic anhydrase 9, ZINC ION
著者Leitans, J, Tars, K.
登録日2017-12-28
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6FE2
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Three dimensional structure of human carbonic anhydrase IX
分子名称: Carbonic anhydrase 9, ZINC ION
著者Leitans, J, Tars, K.
登録日2017-12-28
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6FE1
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BU of 6fe1 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide.
分子名称: 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 9, ZINC ION
著者Leitans, J, Tars, K.
登録日2017-12-28
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
7A05
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BU of 7a05 by Molmil
NMR structure of D3-D4 domains of Vibrio vulnificus ribosomal protein S1
分子名称: 30S ribosomal protein S1
著者Qureshi, N.S, Matzel, T, Cetiner, E.C, Schnieders, S, Jonker, H.R.A, Schwalbe, H, Fuertig, B.
登録日2020-08-06
公開日2021-06-23
最終更新日2024-01-17
実験手法SOLUTION NMR
主引用文献NMR structure of the Vibrio vulnificus ribosomal protein S1 domains D3 and D4 provides insights into molecular recognition of single-stranded RNAs.
Nucleic Acids Res., 49, 2021
6R8N
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BU of 6r8n by Molmil
STRUCTURE DETERMINATION OF THE TETRAHEDRAL AMINOPEPTIDASE TET2 FROM P. HORIKOSHII BY USE OF COMBINED SOLID-STATE NMR, SOLUTION-STATE NMR AND EM DATA 4.1 A, FOLLOWED BY REAL_SPACE_REFINEMENT AT 4.1 A
分子名称: Tetrahedral aminopeptidase, ZINC ION
著者Colletier, J.-P, Gauto, D, Estrozi, L, Favier, A, Effantin, G, Schoehn, G, Boisbouvier, J, Schanda, P.
登録日2019-04-02
公開日2019-08-14
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (4.1 Å), SOLUTION NMR
主引用文献Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex.
Nat Commun, 10, 2019
6G9U
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BU of 6g9u by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
分子名称: 4-[2-[3-(cyclooctylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid, Carbonic anhydrase 9, ZINC ION
著者Leitans, J, Tars, K.
登録日2018-04-11
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
6G98
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BU of 6g98 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
分子名称: 4-[2-[3-(cyclododecylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid, Carbonic anhydrase 9, ZINC ION
著者Leitans, J, Tars, K.
登録日2018-04-10
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
Oncotarget, 9, 2018
1GIG
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BU of 1gig by Molmil
REFINED THREE-DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A MURINE IGG1, LAMBDA ANTIBODY
分子名称: IGG1-KAPPA HC19 FAB (HEAVY CHAIN), IGG1-KAPPA HC19 FAB (LIGHT CHAIN)
著者Bizebard, T, Knossow, M.
登録日1993-01-20
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined three-dimensional structure of the Fab fragment of a murine IgGl,lambda antibody.
Acta Crystallogr.,Sect.D, 50, 1994
5NFO
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BU of 5nfo by Molmil
Human JMJD7 in complex with Mn and 2OG in the P21212 form
分子名称: 2-OXOGLUTARIC ACID, GLYCEROL, JmjC domain-containing protein 7, ...
著者Chowdhury, R, Markolovic, S, Schofield, C.J.
登録日2017-03-14
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.173 Å)
主引用文献(3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.
To Be Published
5NFN
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BU of 5nfn by Molmil
JMJD7 IN COMPLEX WITH MN AND 2OG IN THE H32 FORM
分子名称: 2-OXOGLUTARIC ACID, GLYCEROL, JmjC domain-containing protein 7, ...
著者Chowdhury, R, Markolovic, S, Schofield, C.J.
登録日2017-03-14
公開日2018-03-14
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (2.982 Å)
主引用文献(3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.
To Be Published
7BBV
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BU of 7bbv by Molmil
Pectate lyase B from Verticillium dahliae
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Pectate lyase B, ...
著者Safran, J, Habrylo, O, Bouckaert, J, Pau Roblot, C, Senechal, F, Pelloux, J.
登録日2020-12-18
公開日2022-07-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The specificity of pectate lyase VdPelB from Verticilium dahliae is highlighted by structural, dynamical and biochemical characterizations.
Int.J.Biol.Macromol., 231, 2023
1X94
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BU of 1x94 by Molmil
Crystal Structure of a Hypothetical protein
分子名称: putative Phosphoheptose isomerase
著者Seetharaman, J, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-08-19
公開日2004-09-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of two putative phosphoheptose isomerases.
Proteins, 63, 2006
2VIU
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BU of 2viu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIS
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BU of 2vis by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIT
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BU of 2vit by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
6GS4
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BU of 6gs4 by Molmil
Crystal structure of peptide transporter DtpA-nanobody in complex with valganciclovir
分子名称: DODECYL-BETA-D-MALTOSIDE, Dipeptide and tripeptide permease A, [(2~{S})-2-[(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)methoxy]-3-oxidanyl-propyl] (2~{S})-2-azanyl-3-methyl-butanoate, ...
著者Ural-Blimke, Y, Flayhan, A, Quistgaard, E.M, Loew, C.
登録日2018-06-13
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.
J. Am. Chem. Soc., 141, 2019
6GS7
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Crystal structure of peptide transporter DtpA-nanobody in glycine buffer
分子名称: Dipeptide and tripeptide permease A, nanobody
著者Ural-Blimke, Y, Flayhan, A, Quistgaard, E.M, Loew, C.
登録日2018-06-13
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.
J. Am. Chem. Soc., 141, 2019
6GS1
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BU of 6gs1 by Molmil
Crystal structure of peptide transporter DtpA-nanobody in MES buffer
分子名称: Dipeptide and tripeptide permease A, Nanobody 00
著者Ural-Blimke, Y, Flayhan, A, Loew, C, Quistgaard, E.M.
登録日2018-06-13
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.
J. Am. Chem. Soc., 141, 2019
2EA2
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h-MetAP2 complexed with A773812
分子名称: 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.H.
登録日2007-01-30
公開日2008-02-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids
Bioorg.Med.Chem.Lett., 17, 2007
2EA4
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h-MetAP2 complexed with A797859
分子名称: 2-(2-AMINOETHOXY)-3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.H.
登録日2007-01-30
公開日2008-02-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids
Bioorg.Med.Chem.Lett., 17, 2007
1YW7
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h-MetAP2 complexed with A444148
分子名称: 5-METHYL-2-[(PHENYLSULFONYL)AMINO]BENZOIC ACID, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Park, C.H.
登録日2005-02-17
公開日2006-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and optimization of anthranilic acid sulfonamides as inhibitors of methionine aminopeptidase-2: a structural basis for the reduction of albumin binding.
J.Med.Chem., 49, 2006

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