6GS4
Crystal structure of peptide transporter DtpA-nanobody in complex with valganciclovir
Summary for 6GS4
Entry DOI | 10.2210/pdb6gs4/pdb |
Descriptor | Dipeptide and tripeptide permease A, nanobody, [(2~{S})-2-[(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)methoxy]-3-oxidanyl-propyl] (2~{S})-2-azanyl-3-methyl-butanoate, ... (5 entities in total) |
Functional Keywords | peptide transporter, membrane protein, complex with nanobody, slc15 family member |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 2 |
Total formula weight | 70235.34 |
Authors | Ural-Blimke, Y.,Flayhan, A.,Quistgaard, E.M.,Loew, C. (deposition date: 2018-06-13, release date: 2019-01-30, Last modification date: 2024-01-17) |
Primary citation | Ural-Blimke, Y.,Flayhan, A.,Strauss, J.,Rantos, V.,Bartels, K.,Nielsen, R.,Pardon, E.,Steyaert, J.,Kosinski, J.,Quistgaard, E.M.,Low, C. Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1. J. Am. Chem. Soc., 141:2404-2412, 2019 Cited by PubMed: 30644743DOI: 10.1021/jacs.8b11343 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.645 Å) |
Structure validation
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