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5WZZ
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BU of 5wzz by Molmil
The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
分子名称: Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION
著者Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F.
登録日2017-01-19
公開日2017-08-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Genes Dev., 31, 2017
4RM0
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BU of 4rm0 by Molmil
Crystal structure of Norovirus OIF P domain in complex with Lewis a trisaccharide
分子名称: Capsid protein, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z.
登録日2014-10-18
公開日2015-06-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
4RLZ
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BU of 4rlz by Molmil
Crystal structure of Norovirus OIF P domain
分子名称: Capsid protein, GLYCEROL
著者Liu, W, Chen, Y, Tan, M, Xia, M, Li, X, Jiang, X, Rao, Z.
登録日2014-10-18
公開日2015-06-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface.
Plos Pathog., 11, 2015
2LIT
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BU of 2lit by Molmil
NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in reduced states
分子名称: Cytochrome c iso-1, HEME C
著者Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X.
登録日2011-08-31
公開日2011-12-07
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
2LIR
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BU of 2lir by Molmil
NMR Solution Structure of Yeast Iso-1-cytochrome c Mutant P71H in oxidized states
分子名称: Cytochrome c iso-1, HEME C
著者Lan, W, Wang, Z, Yang, Z, Zhu, J, Ying, T, Jiang, X, Zhang, X, Wu, H, Liu, M, Tan, X, Cao, C, Huang, Z.X.
登録日2011-08-31
公開日2011-12-07
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
7YHJ
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BU of 7yhj by Molmil
Effector binding domain of LysR-Type transcription factor LrhA from E. coli
分子名称: DI(HYDROXYETHYL)ETHER, Probable HTH-type transcriptional regulator LrhA, SULFATE ION
著者Xie, C, Jiang, X.
登録日2022-07-13
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.237 Å)
主引用文献Effector binding domain of LysR-Type transcription factor LrhA from E. coli
To Be Published
5VKI
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BU of 5vki by Molmil
Crystal structure of P[19] rotavirus VP8* complexed with mucin core 2
分子名称: GLYCEROL, Outer capsid protein VP4, SULFATE ION, ...
著者Xu, S, Liu, Y, Woodruff, A, Zhong, W, Jiang, X, Kennedy, M.A.
登録日2017-04-21
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.
PLoS Pathog., 13, 2017
5VKS
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BU of 5vks by Molmil
Crystal structure of P[19] rotavirus VP8* complexed with LNFPI
分子名称: GLYCEROL, Outer capsid protein VP4, SULFATE ION, ...
著者Xu, S, Liu, Y, Woodruff, A, Zhong, W, Jiang, X, Kennedy, M.A.
登録日2017-04-22
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.
PLoS Pathog., 13, 2017
5WBL
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BU of 5wbl by Molmil
Crystal structure of the Arabidopsis thaliana Raptor in complex with the TOS peptide of human PRAS40
分子名称: Proline-rich AKT1 substrate 1, Regulatory-associated protein of TOR 1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBK
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BU of 5wbk by Molmil
Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human S6K1
分子名称: Regulatory-associated protein of TOR 1, Ribosomal protein S6 kinase beta-1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBI
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BU of 5wbi by Molmil
Crystal structure of the Arabidopsis thaliana Raptor
分子名称: Regulatory-associated protein of TOR 1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBJ
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BU of 5wbj by Molmil
Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human 4EBP1
分子名称: Eukaryotic translation initiation factor 4E-binding protein 1, Regulatory-associated protein of TOR 1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
7CRZ
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BU of 7crz by Molmil
Crystal structure of human glucose transporter GLUT3 bound with C3361
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Solute carrier family 2, ...
著者Yuan, Y.Y, Zhang, S, Wang, N, Jiang, X, Yan, N.
登録日2020-08-14
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents.
Proc.Natl.Acad.Sci.USA, 118, 2021
7E27
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BU of 7e27 by Molmil
Structure of PfFNT in complex with MMV007839
分子名称: (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter
著者Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J.
登録日2021-02-04
公開日2021-08-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.29 Å)
主引用文献Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Plos Biol., 19, 2021
7E26
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BU of 7e26 by Molmil
Structure of PfFNT in apo state
分子名称: Formate-nitrite transporter
著者Yan, C.Y, Jiang, X, Deng, D, Peng, X, Wang, N, Zhu, A, Xu, H, Li, J.
登録日2021-02-04
公開日2021-08-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.29 Å)
主引用文献Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
Plos Biol., 19, 2021
7C21
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BU of 7c21 by Molmil
Crystal structure of Duvenhage virus phosphoprotein C-terminal domain
分子名称: Phosphoprotein
著者Sugiyama, A, Jiang, X, Maenaka, K, Yao, M, Ose, T.
登録日2020-05-06
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural comparison of the C-terminal domain of functionally divergent lyssavirus P proteins.
Biochem.Biophys.Res.Commun., 529, 2020
7DA5
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BU of 7da5 by Molmil
Cryo-EM structure of the human MCT1 D309N mutant in complex with Basigin-2 in the inward-open conformation.
分子名称: Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-10-14
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
7CKR
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BU of 7ckr by Molmil
Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate BAY-8002 in the outward-open conformation.
分子名称: 2-[[2-chloranyl-5-(phenylsulfonyl)phenyl]carbonylamino]benzoic acid, Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-07-18
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
7CKO
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BU of 7cko by Molmil
Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate 7ACC2 in the inward-open conformation
分子名称: 7-[methyl-(phenylmethyl)amino]-2-oxidanylidene-chromene-3-carboxylic acid, Basigin, Monocarboxylate transporter 1
著者Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C.
登録日2020-07-18
公開日2020-12-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
3MLZ
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BU of 3mlz by Molmil
Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a VI191 V3 peptide
分子名称: HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain
著者Kong, X.-P.
登録日2010-04-18
公開日2010-07-14
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLR
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BU of 3mlr by Molmil
Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a NY5 V3 peptide
分子名称: HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain
著者Kong, X.-P.
登録日2010-04-18
公開日2010-07-14
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLU
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BU of 3mlu by Molmil
Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a ZAM18 V3 peptide
分子名称: HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain
著者Kong, X.-P.
登録日2010-04-18
公開日2010-07-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLT
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BU of 3mlt by Molmil
Crystal structure of anti-HIV-1 V3 Fab 2557 in complex with a UG1033 V3 peptide
分子名称: HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain
著者Kong, X.-P.
登録日2010-04-18
公開日2010-07-14
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLS
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BU of 3mls by Molmil
Crystal structure of anti-HIV-1 V3 mAb 2557 Fab in complex with a HIV-1 gp120 V3 mimotope
分子名称: Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 2557 Fab light chain, Rationally designed V3 mimotope
著者Kong, X.-P.
登録日2010-04-18
公開日2010-07-14
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3MLX
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BU of 3mlx by Molmil
Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with an MN V3 peptide
分子名称: HIV-1 gp120 third variable region (V3) crown, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody 3074 Fab light chain
著者Kong, X.-P.
登録日2010-04-18
公開日2010-07-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010

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