8JA9
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![BU of 8ja9 by Molmil](/molmil-images/mine/8ja9) | Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-03 | 分子名称: | SULFATE ION, Trehalose-binding lipoprotein LpqY, alpha-D-glucopyranose-(1-1)-(2~{S},3~{R},4~{S},5~{S},6~{S})-6-[(2-azanylhydrazinyl)methyl]oxane-2,3,4,5-tetrol | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-10-04 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAA
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![BU of 8jaa by Molmil](/molmil-images/mine/8jaa) | Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-04 | 分子名称: | (2~{S},3~{R},4~{S},5~{S},6~{S})-6-[(2-azanylhydrazinyl)methyl]oxane-2,3,4,5-tetrol, SULFATE ION, Trehalose-binding lipoprotein LpqY | 著者 | Zhang, B, Liang, J, Rao, Z. | 登録日 | 2023-05-05 | 公開日 | 2023-10-04 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC. Proc.Natl.Acad.Sci.USA, 120, 2023
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3B5H
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![BU of 3b5h by Molmil](/molmil-images/mine/3b5h) | |
8KHU
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![BU of 8khu by Molmil](/molmil-images/mine/8khu) | Hepatitis B virus core protein Y132A mutant in complex with THPP derivatives 48 | 分子名称: | (6~{S},7~{R})-6,7-dimethyl-3-(2-oxidanylidenepyrrolidin-1-yl)-~{N}-[3,4,5-tris(fluoranyl)phenyl]-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-5-carboxamide, Capsid protein, GLYCEROL, ... | 著者 | Zhou, Z, Xu, Z.H. | 登録日 | 2023-08-22 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus. J.Med.Chem., 66, 2023
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7Y47
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![BU of 7y47 by Molmil](/molmil-images/mine/7y47) | Crystal structure of bifunctional miltiradiene synthase from selaginella moellendorffii that complexed with GGPP | 分子名称: | Bifunctional diterpene synthase, chloroplastic, GERANYLGERANYL DIPHOSPHATE, ... | 著者 | Ma, X, Tao, Y, Jiang, T. | 登録日 | 2022-06-14 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase. Plant Biotechnol J, 21, 2023
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5WTW
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![BU of 5wtw by Molmil](/molmil-images/mine/5wtw) | |
5WRE
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![BU of 5wre by Molmil](/molmil-images/mine/5wre) | Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01) | 分子名称: | (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ... | 著者 | Zhou, Z, Xu, Z.H. | 登録日 | 2016-12-01 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.946 Å) | 主引用文献 | Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms. Sci Rep, 7, 2017
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2EW5
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![BU of 2ew5 by Molmil](/molmil-images/mine/2ew5) | Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor | 分子名称: | 4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE, COBALT (II) ION, peptide deformylase | 著者 | Cai, J. | 登録日 | 2005-11-02 | 公開日 | 2006-10-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation Protein Sci., 15, 2006
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2EW6
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![BU of 2ew6 by Molmil](/molmil-images/mine/2ew6) | Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor | 分子名称: | (2E)-3-(3,4-DIHYDROXYPHENYL)-N-[2-(4-HYDROXYPHENYL)ETHYL]ACRYLAMIDE, COBALT (II) ION, peptide deformylase | 著者 | Cai, J. | 登録日 | 2005-11-02 | 公開日 | 2006-10-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation Protein Sci., 15, 2006
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2EW7
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![BU of 2ew7 by Molmil](/molmil-images/mine/2ew7) | Crystal Structure of Helicobacter Pylori peptide deformylase | 分子名称: | COBALT (II) ION, peptide deformylase | 著者 | Cai, J. | 登録日 | 2005-11-02 | 公開日 | 2006-10-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation Protein Sci., 15, 2006
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2H1Y
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5T2P
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![BU of 5t2p by Molmil](/molmil-images/mine/5t2p) | Hepatitis B virus core protein Y132A mutant in complex with sulfamoylbenzamide (SBA_R01) | 分子名称: | 4-fluoranyl-3-(4-oxidanylpiperidin-1-yl)sulfonyl-~{N}-[3,4,5-tris(fluoranyl)phenyl]benzamide, CHLORIDE ION, Core protein, ... | 著者 | Zhou, Z, Xu, Z.H. | 登録日 | 2016-08-24 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.693 Å) | 主引用文献 | Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms. Sci Rep, 7, 2017
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6AFR
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![BU of 6afr by Molmil](/molmil-images/mine/6afr) | Crystal Structure of the first bromodomain of human BRD4 in complex with 5-((4-fluoro-1H-imidazol-1-yl)methyl)quinolin-8-ol | 分子名称: | 5-[(4-fluoranylimidazol-1-yl)methyl]quinolin-8-ol, Bromodomain-containing protein 4 | 著者 | Xing, J, Zhang, R.K, Zheng, M.Y, Luo, C, Jiang, X.R. | 登録日 | 2018-08-08 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors Eur J Med Chem, 163, 2018
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7WIX
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![BU of 7wix by Molmil](/molmil-images/mine/7wix) | Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | 登録日 | 2022-01-05 | 公開日 | 2023-01-25 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WIV
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![BU of 7wiv by Molmil](/molmil-images/mine/7wiv) | Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP | 分子名称: | Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | 登録日 | 2022-01-05 | 公開日 | 2023-01-25 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WIU
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![BU of 7wiu by Molmil](/molmil-images/mine/7wiu) | Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state | 分子名称: | Mycobactin import ATP-binding/permease protein IrtA, Mycobactin import ATP-binding/permease protein IrtB | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | 登録日 | 2022-01-05 | 公開日 | 2023-01-25 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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7WIW
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![BU of 7wiw by Molmil](/molmil-images/mine/7wiw) | Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ... | 著者 | Zhang, B, Sun, S, Yang, H, Rao, Z. | 登録日 | 2022-01-05 | 公開日 | 2023-01-25 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14, 2023
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