2EW5

Structure of Helicobacter Pylori peptide deformylase in complex with inhibitor

Summary for 2EW5

• Entry DOI: 10.2210/pdb2ew5/pdb
• Related: 2EW6 2EW7
• Descriptor: peptide deformylase, COBALT (II) ION, 4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE, ... (4 entities in total)
• Functional Keywords: cobalt helicobacter pylori peptide deformylase, inhibitor, hydrolase
• Biological source: Helicobacter pylori
• Total number of polymer chains: 1
• Total formula weight: 21434.79

Authors

Cai, J. (deposition date: 2005-11-02, release date: 2006-10-24, Last modification date: 2023-10-25)

• Primary citation: Cai, J.,Han, C.,Hu, T.,Zhang, J.,Wu, D.,Wang, F.,Liu, Y.,Ding, J.,Chen, K.,Yue, J.,Shen, X.,Jiang, H.; Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation; Protein Sci., 15:2071-2081, 2006; PubMed: 16882991; DOI: 10.1110/ps.062238406

Experimental method

X-RAY DIFFRACTION (2.2 Å)