5T2P

Hepatitis B virus core protein Y132A mutant in complex with sulfamoylbenzamide (SBA_R01)

Summary for 5T2P

Entry DOI	10.2210/pdb5t2p/pdb
Descriptor	Core protein, 4-fluoranyl-3-(4-oxidanylpiperidin-1-yl)sulfonyl-~{N}-[3,4,5-tris(fluoranyl)phenyl]benzamide, ISOPROPYL ALCOHOL, ... (7 entities in total)
Functional Keywords	hepatitis b virus, hbv, core protein, capsid, y132a dimer, y132a hexamer, sulfamoylbenzamide, sba_r01, viral protein
Biological source	Hepatitis B virus (HBV)
Total number of polymer chains	6
Total formula weight	108726.59
Authors	Zhou, Z.,Xu, Z.H. (deposition date: 2016-08-24, release date: 2017-02-22, Last modification date: 2023-11-08)
Primary citation	Zhou, Z.,Hu, T.,Zhou, X.,Wildum, S.,Garcia-Alcalde, F.,Xu, Z.,Wu, D.,Mao, Y.,Tian, X.,Zhou, Y.,Shen, F.,Zhang, Z.,Tang, G.,Najera, I.,Yang, G.,Shen, H.C.,Young, J.A.,Qin, N. Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms. Sci Rep, 7:42374-42374, 2017 Cited by PubMed: 28205569 DOI: 10.1038/srep42374 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.693 Å)

Structure validation