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8UP7
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Structure of atypical asparaginase from Rhodospirillum rubrum (mutant K19A)
分子名称: Asparaginase, CHLORIDE ION
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-21
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP8
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BU of 8up8 by Molmil
Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21F, complex with L-Asp)
分子名称: ASPARTIC ACID, Asparaginase, CHLORIDE ION, ...
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-21
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UOW
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BU of 8uow by Molmil
Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21A)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Asparaginase
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
8UP3
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BU of 8up3 by Molmil
Structure of atypical asparaginase from Rhodospirillum rubrum (mutant Y21F)
分子名称: 1,2-ETHANEDIOL, ASPARTIC ACID, Asparaginase, ...
著者Lubkowski, J, Wlodawer, A, Zhang, D.
登録日2023-10-20
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.
Protein Sci., 33, 2024
2MRO
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BU of 2mro by Molmil
Structure of the complex of ubiquitin and the UBA domain from DNA-damage-inducible 1 protein (Ddi1)
分子名称: DNA damage-inducible protein 1, Polyubiquitin-B
著者Zhang, D, Fushman, D.
登録日2014-07-14
公開日2015-02-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
2MR9
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BU of 2mr9 by Molmil
NMR structure of UBA domain of DNA-damage-inducible 1 protein (Ddi1)
分子名称: DNA damage-inducible protein 1
著者Zhang, D, Fushman, D.
登録日2014-07-02
公開日2015-02-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献DNA-Damage-Inducible 1 Protein (Ddi1) Contains an Uncharacteristic Ubiquitin-like Domain that Binds Ubiquitin.
Structure, 23, 2015
8P3Z
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BU of 8p3z by Molmil
Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3Y
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Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
8P3X
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BU of 8p3x by Molmil
Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 1
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H.
登録日2023-05-18
公開日2023-08-30
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.
Nature, 621, 2023
3NS8
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BU of 3ns8 by Molmil
Crystal structure of an open conformation of Lys48-linked diubiquitin at pH 7.5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ubiquitin
著者Zhang, D, LaRonde-LeBlanc, N, Fushman, D.
登録日2010-07-01
公開日2011-07-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Structural and biochemical studies of the open state of Lys48-linked diubiquitin.
Biochim.Biophys.Acta, 1823, 2012
4YH4
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BU of 4yh4 by Molmil
Crystal structure of human BRD4(1) in complex with 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19d)
分子名称: 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one, Bromodomain-containing protein 4, GLYCEROL, ...
著者Lakshminarasimhan, D, White, A, Suto, R.K.
登録日2015-02-26
公開日2016-01-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
Bioorg.Med.Chem.Lett., 25, 2015
8UK6
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BU of 8uk6 by Molmil
Candida albicans glutaminyl tRNA synthetase (GLN4) in complex with N-pyrimidinyl-beta-thiophenylacrylamide
分子名称: (2E)-N-(pyrimidin-2-yl)-3-(thiophen-2-yl)prop-2-enamide, ZINC ION, glutamine--tRNA ligase
著者Sychantha, D, Wright, G.D.
登録日2023-10-12
公開日2024-03-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-beta-thiophenylacrylamides exerts highly selective antifungal activity.
Cell Chem Biol, 31, 2024
1H6H
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BU of 1h6h by Molmil
Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate
分子名称: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, GLYCEROL, NEUTROPHIL CYTOSOL FACTOR 4
著者Karathanassis, D, Bravo, J, Pacold, M, Perisic, O, Williams, R.L.
登録日2001-06-15
公開日2001-11-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate
Mol.Cell, 8, 2001
2K57
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BU of 2k57 by Molmil
Solution NMR Structure of Putative Lipoprotein from Pseudomonas syringae Gene Locus PSPTO2350. Northeast Structural Genomics Target PsR76A.
分子名称: Putative Lipoprotein
著者Hang, D, Aramini, J.A, Rossi, P, Wang, D, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-25
公開日2008-09-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Putative Lipoprotein from Pseudomonas syringae Gene Locus PSPTO2350. Northeast Structural Genomics Target PsR76A.
To be Published
2IWL
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BU of 2iwl by Molmil
Structure of the PX Domain of Phosphoinositide 3-Kinase-C2alpha
分子名称: PHOSPHATIDYLINOSITOL-4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING ALPHA POLYPEPTIDE, SULFATE ION
著者Karathanassis, D, Bravo, J, Williams, R.L.
登録日2006-07-01
公開日2006-10-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Membrane Binding Analysis of the Phox Homology Domain of Phosphoinositide 3-Kinase- C2{Alpha}.
J.Biol.Chem., 281, 2006
4CQO
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BU of 4cqo by Molmil
Structure of the human CNOT1 superfamily homology domain in complex with a Nanos1 peptide
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, NANOS HOMOLOG 1
著者Raisch, T, Jonas, S, Weichenrieder, O, Bhandari, D, Izaurralde, E.
登録日2014-02-21
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Nanos-Mediated Recruitment of the Ccr4-not Complex and Translational Repression
Genes Dev., 28, 2014
8Y0F
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BU of 8y0f by Molmil
Solution NMR structure of the PTK7-binding DNA aptamer sgc8c
分子名称: DNA
著者He, A, Wan, L, Guo, P, Han, D.
登録日2024-01-22
公開日2024-06-26
最終更新日2024-07-24
実験手法SOLUTION NMR
主引用文献Structure-based investigation of a DNA aptamer targeting PTK7 reveals an intricate 3D fold guiding functional optimization.
Proc.Natl.Acad.Sci.USA, 121, 2024
8X4F
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BU of 8x4f by Molmil
Solution NMR structure of a DNA hairpin formed by pure CTG repeats
分子名称: DNA (5'-D(*GP*CP*TP*GP*CP*TP*GP*CP*TP*GP*CP*TP*GP*C)-3'), SODIUM ION
著者Guo, P, Wan, L, Han, D.
登録日2023-11-15
公開日2024-02-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献High-Resolution NMR Structures of Intrastrand Hairpins Formed by CTG Trinucleotide Repeats.
Acs Chem Neurosci, 15, 2024
8X1V
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BU of 8x1v by Molmil
NMR structure of a bimolecular parallel G-quadruplex formed by AAGGG repeats from pathogenic RFC1 gene
分子名称: DNA (5'-D(*AP*AP*GP*GP*GP*AP*AP*GP*GP*GP*AP*A)-3')
著者Wang, Y, Guo, P, Han, D.
登録日2023-11-08
公開日2024-01-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS.
Nucleic Acids Res., 52, 2024
6PLF
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BU of 6plf by Molmil
Crystal structure of human PHGDH complexed with Compound 1
分子名称: 1,2-ETHANEDIOL, 4-{(1S)-1-[(5-chloro-6-{[(5S)-2-oxo-1,3-oxazolidin-5-yl]methoxy}-1H-indole-2-carbonyl)amino]-2-hydroxyethyl}benzoic acid, D-3-phosphoglycerate dehydrogenase
著者Olland, A, Lakshminarasimhan, D, White, A, Suto, R.K.
登録日2019-06-30
公開日2019-07-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.
Bioorg.Med.Chem.Lett., 29, 2019
4RIM
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BU of 4rim by Molmil
Native structure of intercalation-locked DNA tetraplex
分子名称: DNA (5'-D(*AP*CP*TP*CP*GP*GP*AP*TP*GP*AP*T)-3')
著者Tripathi, S.K, Zhang, D, Paukstelis, P.
登録日2014-10-06
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献An intercalation-locked parallel-stranded DNA tetraplex.
Nucleic Acids Res., 43, 2015
4RIP
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BU of 4rip by Molmil
BromoUracil substituted structure of intercalation-locked DNA tetraplex
分子名称: DNA (5'-D(*AP*CP*(BRU)P*CP*GP*GP*AP*(BRU)P*GP*AP*T)-3')
著者Tripathi, S.K, Zhang, D, Paukstelis, P.
登録日2014-10-07
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An intercalation-locked parallel-stranded DNA tetraplex.
Nucleic Acids Res., 43, 2015
2I9T
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BU of 2i9t by Molmil
Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter
分子名称: 5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*CP*TP*G)-3', 5'-D(*CP*AP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*AP*CP*T)-3', Nuclear factor NF-kappa-B p105 subunit, ...
著者Escalante, C.R, Shen, L, Thanos, D, Aggarwal, A.K.
登録日2006-09-06
公開日2007-02-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter
Structure, 10, 2002
6IS9
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Crystal Structure of ZmMOC1
分子名称: Monokaryotic chloroplast 1
著者Lin, Z, Lin, H, Zhang, D, Yuan, C.
登録日2018-11-15
公開日2019-10-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6J23
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Crystal structure of arabidopsis ADAL complexed with GMP
分子名称: Adenosine/AMP deaminase family protein, GUANOSINE-5'-MONOPHOSPHATE, ZINC ION
著者Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J.
登録日2018-12-30
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing.
Rna Biol., 16, 2019

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