4CQO
Structure of the human CNOT1 superfamily homology domain in complex with a Nanos1 peptide
Summary for 4CQO
Entry DOI | 10.2210/pdb4cqo/pdb |
Descriptor | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, NANOS HOMOLOG 1 (3 entities in total) |
Functional Keywords | gene regulation, translation, deadenylation, translational repression, protein complex, development, short linear motif |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm, P-body: A5YKK6 Cytoplasm, perinuclear region: Q8WY41 |
Total number of polymer chains | 4 |
Total formula weight | 126892.52 |
Authors | Raisch, T.,Jonas, S.,Weichenrieder, O.,Bhandari, D.,Izaurralde, E. (deposition date: 2014-02-21, release date: 2014-04-23, Last modification date: 2023-12-20) |
Primary citation | Bhandari, D.,Raisch, T.,Weichenrieder, O.,Jonas, S.,Izaurralde, E. Structural Basis for the Nanos-Mediated Recruitment of the Ccr4-not Complex and Translational Repression Genes Dev., 28:888-, 2014 Cited by PubMed: 24736845DOI: 10.1101/GAD.237289.113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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