2IWL
Structure of the PX Domain of Phosphoinositide 3-Kinase-C2alpha
Summary for 2IWL
| Entry DOI | 10.2210/pdb2iwl/pdb |
| Descriptor | PHOSPHATIDYLINOSITOL-4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING ALPHA POLYPEPTIDE, SULFATE ION (3 entities in total) |
| Functional Keywords | pi3k, kinase, px domain, transferase, phosphoinositide 3-kinase, phosphorylation, nuclear protein, phosphoinositide |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Cell membrane : O00443 |
| Total number of polymer chains | 1 |
| Total formula weight | 16754.15 |
| Authors | Karathanassis, D.,Bravo, J.,Williams, R.L. (deposition date: 2006-07-01, release date: 2006-10-18, Last modification date: 2018-01-24) |
| Primary citation | Stahelin, R.V.,Karathanassis, D.,Bruzik, K.S.,Waterfield, M.D.,Bravo, J.,Williams, R.L.,Cho, W. Structural and Membrane Binding Analysis of the Phox Homology Domain of Phosphoinositide 3-Kinase- C2{Alpha}. J.Biol.Chem., 281:39396-, 2006 Cited by PubMed: 17038310DOI: 10.1074/JBC.M607079200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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