6AKK
 
 | | Crystal structure of the second Coiled-coil domain of SIKE1 | | 分子名称: | GLYCEROL, Suppressor of IKBKE 1 | | 著者 | Zhou, L, Chen, M, Zhou, Z.C. | | 登録日 | 2018-09-02 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
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6AKL
 | | Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain | | 分子名称: | Striatin-3, Suppressor of IKBKE 1 | | 著者 | Zhou, L, Chen, M, Zhou, Z.C. | | 登録日 | 2018-09-02 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.
Cell Discov, 5, 2019
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7X4I
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5YF4
 | | A kinase complex MST4-MOB4 | | 分子名称: | MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION | | 著者 | Chen, M, Zhou, Z.C. | | 登録日 | 2017-09-20 | | 公開日 | 2018-08-15 | | 最終更新日 | 2018-09-26 | | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | | 主引用文献 | The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer.
J. Biol. Chem., 293, 2018
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7TJE
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7TJG
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7TJM
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7TJD
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5WRO
 | | Crystal structure of Drosophila enolase | | 分子名称: | CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ... | | 著者 | Zhang, Z, Shi, Z. | | 登録日 | 2016-12-02 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.015 Å) | | 主引用文献 | Crystal structure of enolase from Drosophila melanogaster.
Acta Crystallogr F Struct Biol Commun, 73, 2017
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4LGE
 | | Crystal structure of clAP1 BIR3 bound to T3261256 | | 分子名称: | (4S,6aR,7aS)-5-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]octahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-4-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Dougan, D.R. | | 登録日 | 2013-06-27 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists.
Bioorg.Med.Chem., 21, 2013
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4LGU
 | | Crystal structure of clAP1 BIR3 bound to T3226692 | | 分子名称: | (3S,8aR)-N-((R)-chroman-4-yl)-2-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)octahydropyrrolo[1,2-a]pyrazine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Dougan, D.R, Mol, C.D, Snell, G.P. | | 登録日 | 2013-06-28 | | 公開日 | 2013-08-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design, stereoselective synthesis, and biological evaluation of novel tri-cyclic compounds as inhibitor of apoptosis proteins (IAP) antagonists.
Bioorg.Med.Chem., 21, 2013
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4HY4
 | | Crystal structure of cIAP1 BIR3 bound to T3170284 | | 分子名称: | (3S,8aR)-2-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]octahydropyrrolo[1,2-a]pyrazine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Dougan, D.R, Mol, C.D, Snell, G.P. | | 登録日 | 2012-11-12 | | 公開日 | 2013-01-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.249 Å) | | 主引用文献 | Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2-a]pyrazine Scaffold as a Novel Proline Mimetic.
J.Med.Chem., 56, 2013
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4HY5
 | | Crystal structure of cIAP1 BIR3 bound to T3256336 | | 分子名称: | (3S,7R,8aR)-2-{(2S)-2-(4,4-difluorocyclohexyl)-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]-7-ethoxyoctahydropyrrolo[1,2-a]pyrazine-3-carboxamide, Baculoviral IAP repeat-containing protein 2, ZINC ION | | 著者 | Dougan, D.R, Snell, G.P. | | 登録日 | 2012-11-13 | | 公開日 | 2013-01-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | | 主引用文献 | Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2-a]pyrazine Scaffold as a Novel Proline Mimetic.
J.Med.Chem., 56, 2013
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4HY0
 | | Crystal structure of XIAP BIR3 with T3256336 | | 分子名称: | (3S,7R,8aR)-2-{(2S)-2-(4,4-difluorocyclohexyl)-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(4R)-3,4-dihydro-2H-chromen-4-yl]-7-ethoxyoctahydropyrrolo[1,2-a]pyrazine-3-carboxamide, E3 ubiquitin-protein ligase XIAP, ZINC ION | | 著者 | Snell, G.S, Dougan, D.R. | | 登録日 | 2012-11-12 | | 公開日 | 2013-01-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2-a]pyrazine Scaffold as a Novel Proline Mimetic.
J.Med.Chem., 56, 2013
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8HEW
 | | Potato 14-3-3 St14f | | 分子名称: | 14-3-3 protein, StFDL1 peptide | | 著者 | Taoka, K, Kawahara, I, Shinya, S, Harada, K, Muranaka, T, Furuita, K, Nakagawa, A, Fujiwara, T, Tsuji, H, Kojima, C. | | 登録日 | 2022-11-08 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening.
Plant J., 112, 2022
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3CG7
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3CM6
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9ETU
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9EQ7
 | | Halobacterium salinarum archaellum filament | | 分子名称: | 2-O-sulfo-beta-D-glucopyranuronic acid-(1-4)-3-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-beta-D-glucopyranuronic acid-(1-4)-beta-D-glucopyranose, Archaellin | | 著者 | Grossman-Haham, I, Shahar, A. | | 登録日 | 2024-03-21 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility
To Be Published
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