1AFR
 
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6JJ8
 | | Crystal structure of OsHXK6-ATP-Mg2+ complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | | 登録日 | 2019-02-25 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of OsHXK6-ATP-Mg2+ complex
To Be Published
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1XDO
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1XDP
 | | Crystal Structure of the E.coli Polyphosphate Kinase in complex with AMPPNP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyphosphate kinase | | 著者 | Zhu, Y, Huang, W, Lee, S.S, Xu, W. | | 登録日 | 2004-09-07 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a polyphosphate kinase and its implications for polyphosphate synthesis
Embo Rep., 6, 2005
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8YRF
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8K6Z
 | | NMR structure of human leptin | | 分子名称: | Leptin | | 著者 | Fan, X, Qin, R, Yuan, W, Fan, J, Huang, W, Lin, Z. | | 登録日 | 2023-07-26 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of human leptin reveals a conformational plasticity important for receptor recognition.
Structure, 32, 2024
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6E53
 | | Structure of TERT in complex with a novel telomerase inhibitor | | 分子名称: | MAGNESIUM ION, RNA/DNA hairpin, Telomerase reverse transcriptase, ... | | 著者 | Hernandez-Sanchez, W, Huang, W, Plucinsky, B, Garcia-Vazquez, N, Berdis, A.J, Skordalakes, E, Taylor, D.J. | | 登録日 | 2018-07-19 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity.
Plos Biol., 17, 2019
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2PGH
 | | STRUCTURE DETERMINATION OF AQUOMET PORCINE HEMOGLOBIN AT 2.8 ANGSTROM RESOLUTION | | 分子名称: | HEMOGLOBIN (AQUO MET) (ALPHA CHAIN), HEMOGLOBIN (AQUO MET) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Katz, D.S, White, S.P, Huang, W, Kumar, R, Christianson, D.W. | | 登録日 | 1994-09-16 | | 公開日 | 1994-11-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure determination of aquomet porcine hemoglobin at 2.8 A resolution.
J.Mol.Biol., 244, 1994
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1YIS
 | | Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase | | 分子名称: | SULFATE ION, adenylosuccinate lyase | | 著者 | Symersky, J, Schormann, N, Lu, S, Zhang, Y, Karpova, E, Qiu, S, Huang, W, Cao, Z, Zhou, J, Luo, M, Arabshahi, A, McKinstry, A, Luan, C.-H, Luo, D, Johnson, D, An, J, Tsao, J, Delucas, L, Shang, Q, Gray, R, Li, S, Bray, T, Chen, Y.-J, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2005-01-12 | | 公開日 | 2005-01-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
To be Published
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1J8E
 | | Crystal structure of ligand-binding repeat CR7 from LRP | | 分子名称: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 | | 著者 | Simonovic, M, Dolmer, K, Huang, W, Strickland, D.K, Volz, K, Gettins, P.G.W. | | 登録日 | 2001-05-21 | | 公開日 | 2001-12-19 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
Biochemistry, 40, 2001
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2B34
 | | Structure of MAR1 Ribonuclease from Caenorhabditis elegans | | 分子名称: | MAR1 Ribonuclease | | 著者 | Schormann, N, Karpova, E, Li, S, Symersky, J, Zhang, Y, Lu, S, Zhou, Q, Lin, G, Cao, Z, Luo, M, Qiu, S, Luan, C.-H, Luo, D, Huang, W, Shang, Q, McKinstry, A, An, J, Tsao, J, Carson, M, Stinnett, M, Chen, Y, Johnson, D, Gary, R, Arabshahi, A, Bunzel, R, Bray, T, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2005-09-19 | | 公開日 | 2005-09-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.141 Å) | | 主引用文献 | Structure of MAR1 Ribonuclease from Caenorhabditis elegans
To be Published
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8FCK
 | | Structure of the vertebrate augmin complex | | 分子名称: | HAUS augmin like complex subunit 2 L homeolog, Green fluorescent protein chimera, HAUS augmin like complex subunit 4 L homeolog, ... | | 著者 | Travis, S.M, Huang, W, Zhang, R, Petry, S. | | 登録日 | 2022-12-01 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (6.88 Å) | | 主引用文献 | Integrated model of the vertebrate augmin complex.
Nat Commun, 14, 2023
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1ONR
 | | STRUCTURE OF TRANSALDOLASE B | | 分子名称: | TRANSALDOLASE B | | 著者 | Jia, J, Huang, W, Lindqvist, Y, Schneider, G. | | 登録日 | 1996-08-13 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family.
Structure, 4, 1996
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3JBT
 | | Atomic structure of the Apaf-1 apoptosome | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ... | | 著者 | Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y. | | 登録日 | 2015-10-15 | | 公開日 | 2015-11-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
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4IU9
 | | Crystal structure of a membrane transporter | | 分子名称: | Nitrite extrusion protein 2 | | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | | 登録日 | 2013-01-20 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
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4IU8
 | | Crystal structure of a membrane transporter (selenomethionine derivative) | | 分子名称: | NITRATE ION, Nitrite extrusion protein 2 | | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | | 登録日 | 2013-01-20 | | 公開日 | 2013-04-17 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
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2K3N
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2K3O
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2K53
 | | NMR solution structure of A3DK08 protein from Clostridium thermocellum: Northeast Structural Genomics Consortium Target CmR9 | | 分子名称: | A3DK08 Protein | | 著者 | Swapna, G.V.T, Huang, W, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Everett, J, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-06-24 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structure of A3DK08 protein from Clostridium thermocellum: Northeast Structural Genomics Consortium Target CmR9
To be Published
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6JJ7
 | | Crystal structure of OsHXK6-Glc complex | | 分子名称: | Rice hexokinase 6, beta-D-glucopyranose | | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | | 登録日 | 2019-02-25 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of OsHXK6-Glc complex
To Be Published
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6JJ4
 | | Crystal structure of OsHXK6-apo form | | 分子名称: | Hexokinase-6 | | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | | 登録日 | 2019-02-25 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of OsHXK6-apo
To Be Published
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6JJ9
 | | Crystal structure of OsHXK6-Glc-ATP-Mg2+ complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Hexokinase-6, MAGNESIUM ION, ... | | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | | 登録日 | 2019-02-25 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of OsHXK6-Glc-ATP-Mg2+ complex
To Be Published
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7C2E
 | | GLP-1R-Gs complex structure with a small molecule full agonist | | 分子名称: | 2-[[4-[6-[(4-cyano-2-fluoranyl-phenyl)methoxy]pyridin-2-yl]-3,6-dihydro-2~{H}-pyridin-1-yl]methyl]-3-[[(2~{S})-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Ma, H, Yuan, D.P, Huang, W, Wenge, Z, Xu, E. | | 登録日 | 2020-05-07 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-12-16 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insights into the activation of GLP-1R by a small molecule agonist.
Cell Res., 30, 2020
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7DUQ
 | | Cryo-EM structure of the compound 2 and GLP-1-bound human GLP-1 receptor-Gs complex | | 分子名称: | CHOLESTEROL, Glucagon-like peptide 1, Glucagon-like peptide 1 receptor, ... | | 著者 | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2021-01-11 | | 公開日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
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7DUR
 | | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | | 分子名称: | CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2021-01-11 | | 公開日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
Nat Commun, 12, 2021
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