7TUY

Cryo-EM structure of GSK682753A-bound EBI2/GPR183

Summary for 7TUY

• Entry DOI: 10.2210/pdb7tuy/pdb
• EMDB information: 26135
• Descriptor: anti-BRIL Fab Heavy chain, anti-Fab Nanobody, anti-BRIL Fab Light chain, ... (5 entities in total)
• Functional Keywords: ebi2, gpr183, oxysterol, gpcr, signaling, immunity, immunocyte migration, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 117719.90

Authors

Chen, H.,Huang, W.,Li, X. (deposition date: 2022-02-03, release date: 2022-04-13, Last modification date: 2022-07-20)

• Primary citation: Chen, H.,Huang, W.,Li, X.; Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response.; Structure, 30:1016-, 2022; PubMed: 35537452; DOI: 10.1016/j.str.2022.04.006

Experimental method

ELECTRON MICROSCOPY (2.98 Å)