4JR4
 
 | | Crystal structure of Mtb DsbA (Oxidized) | | 分子名称: | Possible conserved membrane or secreted protein, SULFATE ION | | 著者 | Wang, L. | | 登録日 | 2013-03-21 | | 公開日 | 2013-07-17 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | | 主引用文献 | Structure analysis of the extracellular domain reveals disulfide bond forming-protein properties of Mycobacterium tuberculosis Rv2969c.
Protein Cell, 4, 2013
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6A5F
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7XV9
 | | Crystal structure of the Human TR4 DNA-Binding Domain | | 分子名称: | Nuclear receptor subfamily 2 group C member 2, ZINC ION | | 著者 | Liu, Y, Chen, Z. | | 登録日 | 2022-05-21 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023
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7XV8
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7XV6
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7XVA
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6A5G
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8K98
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8K9A
 | | Cryo-EM structure of DSR2-DSAD1 state 2 | | 分子名称: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | | 著者 | Zhang, H, Li, Z, Li, X.Z. | | 登録日 | 2023-07-31 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Insights into the modulation of bacterial NADase activity by phage proteins.
Nat Commun, 15, 2024
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6A5H
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7SLY
 | | Vanin-1 complexed with Compound 27 | | 分子名称: | (8-oxa-2-azaspiro[4.5]decan-2-yl)(2-{[(1S)-1-(pyrazin-2-yl)ethyl]amino}pyrimidin-5-yl)methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, Pantetheinase, ... | | 著者 | Vajdos, F.F. | | 登録日 | 2021-10-25 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
J.Med.Chem., 65, 2022
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7SLX
 | | Vanin-1 complexed with Compound 11 | | 分子名称: | (3R)-1-(2-{[1-(pyrimidin-5-yl)cyclopropyl]amino}pyrimidine-5-carbonyl)piperidine-3-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, Pantetheinase, ... | | 著者 | Vajdos, F.F. | | 登録日 | 2021-10-25 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-26 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
J.Med.Chem., 65, 2022
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7SLV
 | | Vanin-1 complexed with Compound 3 | | 分子名称: | (8-oxa-2-azaspiro[4.5]decan-2-yl)(2-{[(pyrazin-2-yl)methyl]amino}pyrimidin-5-yl)methanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, Pantetheinase, ... | | 著者 | Vajdos, F.F. | | 登録日 | 2021-10-25 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-26 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
J.Med.Chem., 65, 2022
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4Q5J
 | | Crystal structure of SeMet derivative BRI1 in complex with BKI1 | | 分子名称: | BRI1 kinase inhibitor 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein BRASSINOSTEROID INSENSITIVE 1 | | 著者 | Wang, J, Wang, J, Chen, L, Wu, J.W, Wang, Z.X. | | 登録日 | 2014-04-17 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.772 Å) | | 主引用文献 | Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1.
Cell Res., 24, 2014
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4LYG
 | | Crystal structure of human PRS1 E43T mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-07-31 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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6IZQ
 | | PRMT4 bound with a bicyclic compound | | 分子名称: | (2R)-1-(methylamino)-3-(1,3,4,5-tetrahydro-2-benzazepin-2-yl)propan-2-ol, Histone-arginine methyltransferase CARM1 | | 著者 | Xiong, B, Cao, D.Y, Guo, Z.H, Li, Y.L, Li, J, Huang, X, Shen, J.K. | | 登録日 | 2018-12-20 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.449 Å) | | 主引用文献 | Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.
J.Med.Chem., 62, 2019
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4M0U
 | | crystal structure of human PRS1 Q133P mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-08-02 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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4LZN
 | | Crystal structure of human PRS1 D65N mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-07-31 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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4M0P
 | | Crystal structure of human PRS1 M115T mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-08-01 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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4LZO
 | | Crystal structure of human PRS1 A87T mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-07-31 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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2MOX
 | | solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1 | | 分子名称: | Sorbin and SH3 domain-containing protein 1 | | 著者 | Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q. | | 登録日 | 2014-05-07 | | 公開日 | 2014-05-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
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5H6B
 | | Crystal structure of a thermostable lipase from Marine Streptomyces | | 分子名称: | ACETATE ION, IMIDAZOLE, Putative secreted lipase, ... | | 著者 | Hou, S, Zhao, Z, Liu, J. | | 登録日 | 2016-11-11 | | 公開日 | 2017-09-20 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of a lipase from Streptomyces sp. strain W007 - implications for thermostability and regiospecificity
FEBS J., 284, 2017
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5H6G
 | | Crystal structure of a thermostable lipase from Marine Streptomyces | | 分子名称: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Hou, S, Zhao, Z, Liu, J. | | 登録日 | 2016-11-11 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of a lipase from Streptomyces sp. strain W007 - implications for thermostability and regiospecificity
FEBS J., 284, 2017
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5HMH
 | | HDM2 in complex with a 3,3-Disubstituted Piperidine | | 分子名称: | 4-[2-(4-{[(2R,3S)-2-propyl-1-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}-3-{[5-(trifluoromethyl)thiophen-3-yl]oxy}piperidin-3-yl]carbonyl}piperazin-1-yl)phenoxy]butanoic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | | 著者 | Scapin, G. | | 登録日 | 2016-01-16 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.
Acs Med.Chem.Lett., 7, 2016
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7XYV
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