6WKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wku by Molmil](/molmil-images/mine/6wku) | Twelve Chloride Ions Drive Assembly of Human alpha345 Collagen IV NC1 domain | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... | 著者 | Boudko, S.P, Hudson, B.G. | 登録日 | 2020-04-17 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Collagen IV alpha 345 dysfunction in glomerular basement membrane diseases. II. Crystal structure of the alpha 345 hexamer. J.Biol.Chem., 296, 2021
|
|
7VTA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vta by Molmil](/molmil-images/mine/7vta) | |
7VTB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vtb by Molmil](/molmil-images/mine/7vtb) | |
8KB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kb0 by Molmil](/molmil-images/mine/8kb0) | Crystal structure of 01JD-AEAIIVAMV | 分子名称: | Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
|
|
7MWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mwh by Molmil](/molmil-images/mine/7mwh) | Crystal structure of BAZ2A with DNA | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | 著者 | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2021-05-17 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of the BAZ2B TAM domain. Heliyon, 8, 2022
|
|
8KB1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kb1 by Molmil](/molmil-images/mine/8kb1) | Crystal structure of 11JD | 分子名称: | Beta2-microglobulin, MHC class I antigen, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
|
|
7WIJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wij by Molmil](/molmil-images/mine/7wij) | |
8C7Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c7y by Molmil](/molmil-images/mine/8c7y) | Crystal structure of BRAF V600E in complex with a hybrid compound 6 | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, Serine/threonine-protein kinase B-raf, ... | 著者 | Chaikuad, A, Bonnet, P, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-01-17 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor. Eur.J.Med.Chem., 250, 2023
|
|
8C7X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c7x by Molmil](/molmil-images/mine/8c7x) | Crystal structure of BRAF in complex with a hybrid compound 6 | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, Serine/threonine-protein kinase B-raf, ... | 著者 | Chaikuad, A, Bonnet, P, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-01-17 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor. Eur.J.Med.Chem., 250, 2023
|
|
6MKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mkm by Molmil](/molmil-images/mine/6mkm) | Crystallographic solvent mapping analysis of DMSO/Tris bound to APE1 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ... | 著者 | Georgiadis, M.M, He, H, Chen, Q. | 登録日 | 2018-09-25 | 公開日 | 2019-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.673 Å) | 主引用文献 | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1. J. Med. Chem., 62, 2019
|
|
6MK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mk3 by Molmil](/molmil-images/mine/6mk3) | Crystallographic solvent mapping analysis of DMSO bound to APE1 | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase | 著者 | Georgiadis, M.M, He, H, Chen, Q. | 登録日 | 2018-09-24 | 公開日 | 2019-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.478 Å) | 主引用文献 | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1. J. Med. Chem., 62, 2019
|
|
6MKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mko by Molmil](/molmil-images/mine/6mko) | |
6MKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mkk by Molmil](/molmil-images/mine/6mkk) | Crystallographic solvent mapping analysis of DMSO/Mg bound to APE1 | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase, ... | 著者 | Georgiadis, M.M, He, H, Chen, Q. | 登録日 | 2018-09-25 | 公開日 | 2019-01-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.442 Å) | 主引用文献 | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1. J. Med. Chem., 62, 2019
|
|
8HXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hxq by Molmil](/molmil-images/mine/8hxq) | Nanobody1 in complex with human BCMA ECD | 分子名称: | Nanobody1, Tumor necrosis factor receptor superfamily member 17 | 著者 | Sun, Y, Zhang, B. | 登録日 | 2023-01-05 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther, 8, 2023
|
|
8HXR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hxr by Molmil](/molmil-images/mine/8hxr) | Nanobody2 in complex with human BCMA ECD | 分子名称: | Nanobody2, Tumor necrosis factor receptor superfamily member 17 | 著者 | Sun, Y, Zhang, B. | 登録日 | 2023-01-05 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity. Signal Transduct Target Ther, 8, 2023
|
|
8IAY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iay by Molmil](/molmil-images/mine/8iay) | Crystal structure of canine distemper virus hemagglutinin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein | 著者 | Fukuhara, H, Yumoto, K, Sako, M, Kajikawa, M, Ose, T, Hashiguchi, T, Kamishikiryo, J, Maita, N, Kuroki, K, Maenaka, K. | 登録日 | 2023-02-09 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.027 Å) | 主引用文献 | Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination Elife, 2024
|
|
6FIB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fib by Molmil](/molmil-images/mine/6fib) | Structure of human 4-1BB ligand | 分子名称: | Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor ligand superfamily member 9,4-1BBL -CH/CL fusion, Tumor necrosis factor ligand superfamily member 9,Uncharacterized protein | 著者 | Joseph, C, Claus, C, Ferrara, C, von Hirschheydt, T, Prince, C, Funk, D, Klein, C, Benz, J. | 登録日 | 2018-01-17 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy. Sci Transl Med, 11, 2019
|
|
6TRK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6trk by Molmil](/molmil-images/mine/6trk) | Phl p 6 fold stabilized mutant - S46Y | 分子名称: | Pollen allergen Phl p 6, ZINC ION | 著者 | Soh, W.T, Brandstetter, H. | 登録日 | 2019-12-19 | 公開日 | 2020-08-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | In silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization. Front Immunol, 11, 2020
|
|
7E9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e9b by Molmil](/molmil-images/mine/7e9b) | |
6IR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ir2 by Molmil](/molmil-images/mine/6ir2) | Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM2 at 1.4 Angstron resolution | 分子名称: | MCherry fluorescent protein, mCherry's nanobody LaM2 | 著者 | Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X. | 登録日 | 2018-11-09 | 公開日 | 2019-11-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.393 Å) | 主引用文献 | Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry. Protein Sci., 30, 2021
|
|
5LBW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lbw by Molmil](/molmil-images/mine/5lbw) | Structure of the human quinone reductase 2 (NQO2) in complex with volitinib | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, ... | 著者 | Schneider, S, Medard, G, Kuester, B. | 登録日 | 2016-06-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The target landscape of clinical kinase drugs. Science, 358, 2017
|
|
5LBZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lbz by Molmil](/molmil-images/mine/5lbz) | Structure of the human quinone reductase 2 (NQO2) in complex with pacritinib | 分子名称: | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Schneider, S, Medard, G, Kuster, B. | 登録日 | 2016-06-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The target landscape of clinical kinase drugs. Science, 358, 2017
|
|
5LBY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lby by Molmil](/molmil-images/mine/5lby) | Structure of the human quinone reductase 2 (NQO2) in complex with crenolanib | 分子名称: | 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Schneider, S, Medard, G, Kuester, B. | 登録日 | 2016-06-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The target landscape of clinical kinase drugs. Science, 358, 2017
|
|
8KG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8kg5 by Molmil](/molmil-images/mine/8kg5) | Prefusion RSV F Bound to Lonafarnib and D25 Fab | 分子名称: | 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, D25 heavy chain, D25 light chain, ... | 著者 | Yang, Q, Xue, B, Liu, F, Peng, W, Chen, X. | 登録日 | 2023-08-17 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein. Signal Transduct Target Ther, 9, 2024
|
|
7PQV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pqv by Molmil](/molmil-images/mine/7pqv) | MEK1 IN COMPLEX WITH COMPOUND 7 | 分子名称: | 8-(2-chloranyl-4-methoxy-phenyl)-7-fluoranyl-1-piperidin-4-yl-imidazo[4,5-c]quinoline, CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1, ... | 著者 | Moebitz, H. | 登録日 | 2021-09-20 | 公開日 | 2022-03-16 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action. J.Med.Chem., 65, 2022
|
|