6TRK

Phl p 6 fold stabilized mutant - S46Y

Summary for 6TRK

Entry DOI	10.2210/pdb6trk/pdb
Descriptor	Pollen allergen Phl p 6, ZINC ION (3 entities in total)
Functional Keywords	phleum pratense, grass pollen allergen, stabilized fold mutant, phl p 6, allergen
Biological source	Phleum pratense (timothy grass)
Total number of polymer chains	2
Total formula weight	24024.22
Authors	Soh, W.T.,Brandstetter, H. (deposition date: 2019-12-19, release date: 2020-08-12, Last modification date: 2024-01-24)
Primary citation	Winter, P.,Stubenvoll, S.,Scheiblhofer, S.,Joubert, I.A.,Strasser, L.,Briganser, C.,Soh, W.T.,Hofer, F.,Kamenik, A.S.,Dietrich, V.,Michelini, S.,Laimer, J.,Lackner, P.,Horejs-Hoeck, J.,Tollinger, M.,Liedl, K.R.,Brandstetter, J.,Huber, C.G.,Weiss, R. In silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization. Front Immunol, 11:1824-1824, 2020 Cited by PubMed: 33013833 DOI: 10.3389/fimmu.2020.01824 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation