1ZF7
 
 | | GAC Duplex B-DNA | | 分子名称: | 5'-D(*CP*CP*GP*TP*CP*GP*AP*CP*GP*G)-3', CALCIUM ION, SODIUM ION | | 著者 | Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. | | 登録日 | 2005-04-20 | | 公開日 | 2005-05-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | How sequence defines structure: a crystallographic map of DNA structure and conformation.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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7TR6
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | Cas11a, Cas5a, Cas7a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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7TR8
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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7TRA
 | | Cascade complex from type I-A CRISPR-Cas system | | 分子名称: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | | 著者 | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-10 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
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1Z1B
 | | Crystal structure of a lambda integrase dimer bound to a COC' core site | | 分子名称: | 26-MER DNA, 29-MER DNA, 5'-D(*CP*T*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', ... | | 著者 | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | | 登録日 | 2005-03-03 | | 公開日 | 2005-06-28 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | A structural basis for allosteric control of DNA recombination by lambda integrase.
Nature, 435, 2005
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7ZFW
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1XUZ
 | | Crystal structure analysis of sialic acid synthase (NeuB)from Neisseria meningitidis, bound to Mn2+, Phosphoenolpyruvate, and N-acetyl mannosaminitol | | 分子名称: | 5-DEOXY-5-{[(1S)-1-HYDROXYETHYL]AMINO}-D-GLUCITOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... | | 著者 | Gunawan, J, Simard, D, Gilbert, M, Lovering, A.L, Wakarchuk, W.W, Tanner, M.E, Strynadka, N.C. | | 登録日 | 2004-10-26 | | 公開日 | 2004-11-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol.
J.Biol.Chem., 280, 2005
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6UCT
 | | Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant) | | 分子名称: | p9-1 | | 著者 | Llauger, G, Klinke, S, Monti, D, Sycz, G, Cerutti, M.L, Goldbaum, F.A, del Vas, M, Otero, L.H. | | 登録日 | 2019-09-17 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | | 主引用文献 | Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant)
To Be Published
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6UD0
 | | Solution-state NMR structural ensemble of human Tsg101 UEV in complex with K63-linked diubiquitin | | 分子名称: | Tumor susceptibility gene 101 protein, Ubiquitin | | 著者 | Strickland, M, Watanabe, S, Bonn, S.M, Camara, C.M, Fushman, D, Carter, C.A, Tjandra, N. | | 登録日 | 2019-09-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Tsg101/ESCRT-I Recruitment Regulated by the Dual Binding Modes of K63-Linked Diubiquitin
Structure, 2021
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6UG1
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1XWQ
 | | Structure Of A Cold-Adapted Family 8 Xylanase | | 分子名称: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, endo-1,4-beta-xylanase | | 著者 | De Vos, D, Collins, T, Hoyoux, A, Savvides, S.N, Gerday, C, Van Beeumen, J.J, Feller, G. | | 登録日 | 2004-11-02 | | 公開日 | 2005-10-11 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Study of the active site residues of a glycoside hydrolase family 8 xylanase
J.Mol.Biol., 354, 2005
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6TV7
 | | Crystal structure of rsGCaMP in the OFF state (illuminated) | | 分子名称: | CALCIUM ION, SODIUM ION, rsGCaMP | | 著者 | Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D. | | 登録日 | 2020-01-09 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Nat.Biotechnol., 2021
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2P4U
 | | Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus | | 分子名称: | Acid phosphatase 1, PHOSPHATE ION | | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-03-13 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
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7TEY
 | | Cryo-EM structure of SARS-CoV-2 Delta (B.1.617.2) spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. | | 登録日 | 2022-01-06 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.25 Å) | | 主引用文献 | Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants.
Nat Commun, 13, 2022
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1XT4
 | | Urate Oxidase From Aspergillus Flavus Complexed With Guanine | | 分子名称: | GUANINE, Uricase | | 著者 | Retailleau, P, Colloc'h, N, Vivares, D, Bonnete, F, Castro, B, El Hajji, M, Prange, T. | | 登録日 | 2004-10-21 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site.
Acta Crystallogr.,Sect.D, 61, 2005
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6WEK
 | | Structure of cGMP-bound WT TAX-4 reconstituted in lipid nanodiscs | | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | | 著者 | Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. | | 登録日 | 2020-04-02 | | 公開日 | 2020-06-03 | | 最終更新日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
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1XOM
 | | Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Cilomilast | | 分子名称: | 1,2-ETHANEDIOL, CILOMILAST, MAGNESIUM ION, ... | | 著者 | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | | 登録日 | 2004-10-06 | | 公開日 | 2004-12-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
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6WKR
 | | PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome | | 分子名称: | DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R. | | 登録日 | 2020-04-16 | | 公開日 | 2021-02-03 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
Science, 371, 2021
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7S16
 | | Crystal structure of alpha-COP-WD40 domain R57A mutant | | 分子名称: | Coatomer subunit alpha, SODIUM ION | | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | | 登録日 | 2021-09-01 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
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1XPK
 | | CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS HMG-COA SYNTHASE WITH HMG-CoA AND WITH ACETOACETYL-COA AND ACETYLATED CYSTEINE | | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, ... | | 著者 | Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. | | 登録日 | 2004-10-08 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time"
Proc.Natl.Acad.Sci.USA, 47, 2004
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7S22
 | | Crystal structure of alpha-COP-WD40 domain | | 分子名称: | Coatomer subunit alpha | | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | | 登録日 | 2021-09-02 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
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7ZZ5
 | | Cryo-EM structure of "BC open" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, BICARBONATE ION, Pyruvate carboxylase | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7ZZ3
 | | Cryo-EM structure of "BC react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. | | 登録日 | 2022-05-25 | | 公開日 | 2022-10-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | | 主引用文献 | CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
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7S23
 | | Crystal structure of alpha-COP-WD40 domain, Y139A mutant | | 分子名称: | Coatomer subunit alpha | | 著者 | Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S. | | 登録日 | 2021-09-03 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
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7SII
 | | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | | 著者 | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | | 登録日 | 2021-10-14 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Activation of STING by targeting a pocket in the transmembrane domain.
Nature, 604, 2022
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