2QXW
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![BU of 2qxw by Molmil](/molmil-images/mine/2qxw) | Perdeuterated alr2 in complex with idd594 | 分子名称: | Aldose reductase, CITRIC ACID, IDD594, ... | 著者 | Blakeley, M.P, Ruiz, F, Cachau, R, Hazemann, I, Meilleur, F, Mitschler, A, Ginell, S, Afonine, P, Ventura, O, Cousido-Siah, A, Joachimiak, A, Myles, D, Podjarny, A. | 登録日 | 2007-08-13 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (0.8 Å) | 主引用文献 | Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1MKM
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![BU of 1mkm by Molmil](/molmil-images/mine/1mkm) | CRYSTAL STRUCTURE OF THE THERMOTOGA MARITIMA ICLR | 分子名称: | FORMIC ACID, IclR transcriptional regulator, ZINC ION | 著者 | Kim, Y, Zhang, R.G, Joachimiak, A, Skarina, T, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-08-29 | 公開日 | 2002-09-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family. J.Biol.Chem., 277, 2002
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2K4C
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![BU of 2k4c by Molmil](/molmil-images/mine/2k4c) | tRNAPhe-based homology model for tRNAVal refined against base N-H RDCs in two media and SAXS data | 分子名称: | 76-MER | 著者 | Grishaev, A, Ying, J, Canny, M.D, Pardi, A, Bax, A. | 登録日 | 2008-06-04 | 公開日 | 2008-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | 主引用文献 | Solution structure of tRNAVal from refinement of homology model against residual dipolar coupling and SAXS data. J.Biomol.Nmr, 42, 2008
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1MKZ
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![BU of 1mkz by Molmil](/molmil-images/mine/1mkz) | Crystal structure of MoaB protein at 1.6 A resolution. | 分子名称: | ACETIC ACID, Molybdenum cofactor biosynthesis protein B, SULFATE ION | 著者 | Sanishvili, R, Skarina, T, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-08-29 | 公開日 | 2003-04-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J.Biol.Chem., 279, 2004
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1W82
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![BU of 1w82 by Molmil](/molmil-images/mine/1w82) | p38 Kinase crystal structure in complex with small molecule inhibitor | 分子名称: | MITOGEN-ACTIVATED PROTEIN KINASE 14, N-[(3Z)-5-TERT-BUTYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-YLIDENE]-N'-(4-CHLOROPHENYL)UREA | 著者 | Tickle, J, Jhoti, H, Cleasby, A, Devine, L. | 登録日 | 2004-09-16 | 公開日 | 2005-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of Novel P38Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation J.Med.Chem., 48, 2005
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2KZR
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![BU of 2kzr by Molmil](/molmil-images/mine/2kzr) | Solution NMR Structure of Ubiquitin thioesterase OTU1 (EC 3.1.2.-) from Mus musculus, Northeast Structural Genomics Consortium Target MmT2A | 分子名称: | Ubiquitin thioesterase OTU1 | 著者 | Chitayat, S, Gutmanas, A, Lemak, A, Yee, A, Bezsonova, I, Wu, B, Doherty, R.S, Semesi, A, Montelione, G.T, Arrowsmith, C.H, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-06-23 | 公開日 | 2010-07-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Northeast Structural Genomics Consortium Target MmT2A To be Published
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2LF0
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![BU of 2lf0 by Molmil](/molmil-images/mine/2lf0) | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering, NESG target SfR339/OCSP target sf3636 | 分子名称: | Uncharacterized protein yibL | 著者 | Wu, B, Lemak, A, Yee, A, Lee, H, Gutmanas, A, Semesi, A, Garcia, M, Fang, X, Wang, Y, Prestegard, J.H, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | 登録日 | 2011-06-27 | 公開日 | 2011-07-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | 主引用文献 | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering To be Published
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2FAM
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![BU of 2fam by Molmil](/molmil-images/mine/2fam) | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | 著者 | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | 登録日 | 1993-07-20 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states. J.Mol.Biol., 233, 1993
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2FAL
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![BU of 2fal by Molmil](/molmil-images/mine/2fal) | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | 分子名称: | CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | 登録日 | 1993-06-14 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states. J.Mol.Biol., 233, 1993
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2LF3
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![BU of 2lf3 by Molmil](/molmil-images/mine/2lf3) | Solution NMR structure of HopPmaL_281_385 from Pseudomonas syringae pv. maculicola str. ES4326, Midwest Center for Structural Genomics target APC40104.5 and Northeast Structural Genomics Consortium target PsT2A | 分子名称: | Effector protein hopAB3 | 著者 | Wu, B, Yee, A, Houliston, S, Semesi, A, Garcia, M, Singer, A.U, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG), Ontario Centre for Structural Proteomics (OCSP) | 登録日 | 2011-06-28 | 公開日 | 2011-07-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors. Biochemistry, 51, 2012
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7OND
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4C90
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![BU of 4c90 by Molmil](/molmil-images/mine/4c90) | Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility | 分子名称: | ALPHA-GLUCURONIDASE GH115, SODIUM ION | 著者 | Rogowski, A, Basle, A, Farinas, C.S, Solovyova, A, Mortimer, J.C, Dupree, P, Gilbert, H.J, Bolam, D.N. | 登録日 | 2013-10-02 | 公開日 | 2013-11-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Evidence that Gh115 Alpha-Glucuronidase Activity is Dependent on Conformational Flexibility J.Biol.Chem., 289, 2014
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7YC6
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2YAV
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![BU of 2yav by Molmil](/molmil-images/mine/2yav) | ZN INHIBITED SULFUR OXYGENASE REDUCTASE | 分子名称: | ACETATE ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Veith, A, Urich, T, Seyfarth, K, Protze, J, Frazao, C, Kletzin, A. | 登録日 | 2011-02-25 | 公開日 | 2011-12-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Substrate Pathways and Mechanisms of Inhibition in the Sulfur Oxygenase Reductase of Acidianus Ambivalens. Front.Microbiol., 2, 2011
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4CDD
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![BU of 4cdd by Molmil](/molmil-images/mine/4cdd) | Human DPP1 in complex with (2S)-N-((1S)-1-cyano-2-(4-(4-cyanophenyl) phenyl)ethyl)piperidine-2-carboxamide | 分子名称: | (2S)-N-[(2S)-1-AZANYLIDENE-3-[4-(4-CYANOPHENYL)PHENYL]PROPAN-2-YL]PIPERIDINE-2-CARBOXAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Debreczeni, J, Edman, K, Furber, M, Tiden, A, Gardiner, P, Mete, T, Ford, R, Millichip, I, Stein, L, Mather, A, Kinchin, E, Luckhurst, C, Cage, P, Sanghanee, H, Breed, J, Wissler, L. | 登録日 | 2013-10-31 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate. J.Med.Chem., 57, 2014
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7OO4
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5X7S
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![BU of 5x7s by Molmil](/molmil-images/mine/5x7s) | Crystal structure of Paenibacillus sp. 598K alpha-1,6-glucosyltransferase, terbium derivative | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Fujimoto, Z, Kishine, N, Suzuki, N, Momma, M, Ichinose, H, Kimura, A, Funane, K. | 登録日 | 2017-02-27 | 公開日 | 2017-07-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Carbohydrate-binding architecture of the multi-modular alpha-1,6-glucosyltransferase from Paenibacillus sp. 598K, which produces alpha-1,6-glucosyl-alpha-glucosaccharides from starch Biochem. J., 474, 2017
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4CDE
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![BU of 4cde by Molmil](/molmil-images/mine/4cde) | Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AZANYL-N-[(2S)-1-AZANYLIDENE-3-[4-(4-CYANOPHENYL)PHENYL]PROPAN-2-YL]OXANE-4-CARBOXAMIDE, CHLORIDE ION, ... | 著者 | Debreczeni, J, Edman, K, Furber, M, Tiden, A, Gardiner, P, Mete, T, Ford, R, Millichip, I, Stein, L, Mather, A, Kinchin, E, Luckhurst, C, Cage, P, Sanghanee, H, Breed, J, Wissler, L. | 登録日 | 2013-10-31 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate. J.Med.Chem., 57, 2014
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5XAN
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![BU of 5xan by Molmil](/molmil-images/mine/5xan) | Crystal structure of SecDF in I form (P212121 space group) | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POLYETHYLENE GLYCOL (N=34), Protein translocase subunit SecD | 著者 | Tsukazaki, T, Tanaka, Y, Furukwa, A. | 登録日 | 2017-03-14 | 公開日 | 2017-05-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Tunnel Formation Inferred from the I-Form Structures of the Proton-Driven Protein Secretion Motor SecDF Cell Rep, 19, 2017
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5XBP
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![BU of 5xbp by Molmil](/molmil-images/mine/5xbp) | Oxygenase component of 3-nitrotoluene dioxygenase from Diaphorobacter sp. strain DS2 | 分子名称: | 3NT oxygenase alpha subunit, 3NT oxygenase beta subunit, FE (III) ION, ... | 著者 | Ramaswamy, S, Kumari, A, Singh, D, Gurunath, R. | 登録日 | 2017-03-21 | 公開日 | 2017-04-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and functional studies of ferredoxin and oxygenase components of 3-nitrotoluene dioxygenase from Diaphorobacter sp. strain DS2. PLoS ONE, 12, 2017
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7OSD
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7OS8
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![BU of 7os8 by Molmil](/molmil-images/mine/7os8) | |
5R4M
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![BU of 5r4m by Molmil](/molmil-images/mine/5r4m) | PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000513a | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE, ... | 著者 | Talon, R, Krojer, T, Fairhead, M, Sethi, R, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Wright, N, MacLean, E, Renjie, Z, Dias, A, Brennan, P.E, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | 登録日 | 2020-02-24 | 公開日 | 2020-04-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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8UTK
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![BU of 8utk by Molmil](/molmil-images/mine/8utk) | IL-23R minibinder - 23R-B04dslf02IB | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 23R-B04dslf02IB, ... | 著者 | Bera, A.K, Berger, S.A, Kang, A, Baker, D. | 登録日 | 2023-10-31 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell, 2024
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2LF6
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![BU of 2lf6 by Molmil](/molmil-images/mine/2lf6) | Solution NMR structure of HopABPph1448_220_320 from Pseudomonas syringae pv. phaseolicola str. 1448A, Midwest Center for Structural Genomics target APC40132.4 and Northeast Structural Genomics Consortium target PsT3A | 分子名称: | Effector protein hopAB1 | 著者 | Wu, B, Yee, A, Houliston, S, Semesi, A, Garcia, M, Singer, A.U, Savchenko, A, Montelione, G.T, Joachimiak, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG), Ontario Centre for Structural Proteomics (OCSP) | 登録日 | 2011-06-28 | 公開日 | 2011-07-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Analysis of HopPmaL Reveals the Presence of a Second Adaptor Domain Common to the HopAB Family of Pseudomonas syringae Type III Effectors. Biochemistry, 51, 2012
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