7OO4

HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridine Dye

Summary for 7OO4

Entry DOI	10.2210/pdb7oo4/pdb
Descriptor	Haloalkane dehalogenase, CHLORIDE ION, 4-[(E)-2-[1-(7-chloranylheptyl)pyridin-1-ium-4-yl]ethenyl]-N,N-dimethyl-aniline, ... (4 entities in total)
Functional Keywords	halotag, fluorescence, imaging, mammalian cells, fluorescent reporter, channel dye, directed evolution, fluorescent protein
Biological source	Rhodococcus sp.
Total number of polymer chains	1
Total formula weight	34609.42
Authors	Stein, A.,Liang, A.D. (deposition date: 2021-05-26, release date: 2021-07-21, Last modification date: 2024-01-31)
Primary citation	Miro-Vinyals, C.,Stein, A.,Fischer, S.,Ward, T.R.,Deliz Liang, A. HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye. Chembiochem, 22:3398-3401, 2021 Cited by PubMed: 34609782 DOI: 10.1002/cbic.202100424 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation