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4V0Z
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BU of 4v0z by Molmil
o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE CEL7A, COBALT (II) ION, ...
著者Nutt, A, Momeni, M.H, Stahlberg, J.
登録日2014-09-19
公開日2015-09-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Enzyme kinetics by GH7 cellobiohydrolases on chromogenic substrates is dictated by non-productive binding: insights from crystal structures and MD simulation.
Febs J., 2022
8IGS
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BU of 8igs by Molmil
Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRE
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y.
登録日2023-02-21
公開日2023-05-17
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of lambda CII-dependent transcription activation.
Structure, 31, 2023
5W0W
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BU of 5w0w by Molmil
Crystal structure of Protein Phosphatase 2A bound to TIPRL
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ...
著者Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y.
登録日2017-06-01
公開日2018-01-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Methylation-regulated decommissioning of multimeric PP2A complexes.
Nat Commun, 8, 2017
3N9X
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BU of 3n9x by Molmil
Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0
分子名称: GLYCEROL, Phosphotransferase
著者Wernimont, A.K, Hutchinson, A, Sullivan, H, MacKenzie, F, Kozieradzki, I, Chau, I, Lew, J, Senisterra, G, Artz, J, Amani, M, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
登録日2010-05-31
公開日2010-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of Map Kinase from plasmodium berghei, PB000659.00.0
To be Published
3EMW
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BU of 3emw by Molmil
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2) in complex with a 20-residue VASA peptide
分子名称: 1,2-ETHANEDIOL, Peptide (VASA), SPRY domain-containing SOCS box protein 2
著者Filippakopoulos, P, Sharpe, T, Keates, T, Murray, J.W, Savitsky, P, Roos, A.K, Pike, A.C.W, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC)
登録日2008-09-25
公開日2008-10-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J.Mol.Biol., 401, 2010
6TE0
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BU of 6te0 by Molmil
Cryo-EM structure of Euglena gracilis mitochondrial ATP synthase, OSCP/F1/c-ring, rotational state 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit gamma protein, ...
著者Muhleip, A, Amunts, A.
登録日2019-11-10
公開日2019-11-27
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structure of a mitochondrial ATP synthase with bound native cardiolipin.
Elife, 8, 2019
4V4O
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BU of 4v4o by Molmil
Crystal Structure of the Chaperonin Complex Cpn60/Cpn10/(ADP)7 from Thermus Thermophilus
分子名称: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Shimamura, T, Koike-Takeshita, A, Yokoyama, K, Masui, R, Murai, N, Yoshida, M, Taguchi, H, Iwata, S.
登録日2004-05-23
公開日2014-07-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the native chaperonin complex from Thermus thermophilus revealed unexpected asymmetry at the cis-cavity
STRUCTURE, 12, 2004
3ENA
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BU of 3ena by Molmil
Crystal structure of the mimivirus NDK +Kpn-N62L-R107G triple mutant complexed with dGDP
分子名称: 2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside diphosphate kinase
著者Jeudy, S, Lartigue, A, Claverie, J.M, Abergel, C.
登録日2008-09-25
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase.
J.Virol., 83, 2009
8IN9
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BU of 8in9 by Molmil
The structure of the GfsA KSQ-AT didomain in complex with the GfsA ACP domain
分子名称: N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Polyketide synthase
著者Chisuga, T, Murakami, S, Miyanaga, A, Kudo, F, Eguchi, T.
登録日2023-03-09
公開日2023-05-31
最終更新日2023-06-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase.
Acs Chem.Biol., 18, 2023
4V9F
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BU of 4v9f by Molmil
The re-refined crystal structure of the Haloarcula marismortui large ribosomal subunit at 2.4 Angstrom resolution: more complete structure of the L7/L12 and L1 stalk, L5 and LX proteins
分子名称: 23S Ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Gabdulkhakov, A.
登録日2012-11-02
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献Revisiting the Haloarcula marismortui 50S ribosomal subunit model.
Acta Crystallogr.,Sect.D, 69, 2013
4V9O
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BU of 4v9o by Molmil
Control of ribosomal subunit rotation by elongation factor G
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pulk, A, Cate, J.H.D.
登録日2013-05-03
公開日2014-07-09
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Control of ribosomal subunit rotation by elongation factor G.
Science, 340, 2013
5LY1
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BU of 5ly1 by Molmil
JMJD2A/ KDM4A COMPLEXED WITH NI(II) AND Macrocyclic PEPTIDE Inhibitor CP2 (13-mer)
分子名称: CHLORIDE ION, CP2, GLYCEROL, ...
著者King, O.N.F, Chowdhury, R, Kawamura, A, Schofield, C.J.
登録日2016-09-23
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Nat Commun, 8, 2017
5M0D
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BU of 5m0d by Molmil
Structure-based evolution of a hybrid steroid series of Autotaxin inhibitors
分子名称: CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2,Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, GLYCEROL, ...
著者Keune, W.-J, Heidebrecht, T, Perrakis, A.
登録日2016-10-04
公開日2017-08-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.
J. Med. Chem., 60, 2017
5M0E
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BU of 5m0e by Molmil
Structure-based evolution of a hybrid steroid series of Autotaxin inhibitors
分子名称: 7alpha-hydroxycholesterol, CALCIUM ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ...
著者Keune, W.-J, Heidebrecht, T, Perrakis, A.
登録日2016-10-04
公開日2017-08-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.
J. Med. Chem., 60, 2017
4UWU
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BU of 4uwu by Molmil
Lysozyme soaked with a ruthenium based CORM with a pyridine ligand (complex 7)
分子名称: CARBON MONOXIDE, CHLORIDE ION, FORMIC ACID, ...
著者Santos, M.F.A, Mukhopadhyay, A, Romao, M.J, Romao, C.C, Santos-Silva, T.
登録日2014-08-14
公開日2014-12-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献A Contribution to the Rational Design of Ru(Co)3Cl2L Complexes for in Vivo Delivery of Co.
Dalton Trans, 44, 2015
4URS
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BU of 4urs by Molmil
Crystal Structure of GGDEF domain from T.maritima
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE, ...
著者Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J.
登録日2014-07-02
公開日2014-10-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
4UQV
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BU of 4uqv by Molmil
methanococcus jannaschii serine hydroxymethyl-transferase in complex with PLP
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE HYDROXYMETHYLTRANSFERASE
著者Saccoccia, F, Angelucci, F, Ilari, A.
登録日2014-06-25
公開日2014-07-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of Archaeal Serine Hydroxymethyltransferase Reveals Idiosyncratic Features Likely Required to Withstand High Temperatures.
Proteins, 82, 2014
3EVO
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BU of 3evo by Molmil
Crystal structure of the Mimivirus NDK +Kpn mutant complexed with dTDP
分子名称: MAGNESIUM ION, Nucleoside diphosphate kinase, THYMIDINE-5'-DIPHOSPHATE
著者Jeudy, S, Lartigue, A, Claverie, J.M, Abergel, C.
登録日2008-10-13
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase.
J.Virol., 83, 2009
4UY4
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BU of 4uy4 by Molmil
1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide
分子名称: GLYCEROL, HISTONE H3K4ME3, SPINDLIN-4
著者Talon, R, Gileadi, C, Johansson, C, Burgess-Brown, N, Shrestha, L, von Delft, F, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U.
登録日2014-08-28
公開日2014-09-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.862 Å)
主引用文献1.86 A Structure of Human Spindlin-4 Protein in Complex with Histone H3K4Me3 Peptide
To be Published
4V37
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Crystal structure of betaine aldehyde dehydrogenase from spinach showing a thiohemiacetal with 3-aminopropionaldehyde
分子名称: 2-(2-ETHOXYETHOXY)ETHANOL, 3-aminopropan-1-ol, BETAINE ALDEHYDE DEHYDROGENASE, ...
著者Zarate-Romero, A, Munoz-Clares, R.A.
登録日2014-10-16
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of a Stable Thiohemiacetal Involving a Conserved Cysteine in the Substrate Inactivation of S. Oleracea Betaine Aldehyde Dehydrogenase
To be Published
3NG6
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BU of 3ng6 by Molmil
The crystal structure of hemoglobin I from Trematomus newnesi in deoxygenated state obtained through an oxidation/reduction cycle in which potassium hexacyanoferrate and sodium dithionite were alternatively added
分子名称: Hemoglobin subunit alpha-1, Hemoglobin subunit beta-1/2, PROTOPORPHYRIN IX CONTAINING FE
著者Vergara, A, Vitagliano, L, Merlino, A, Sica, F, Marino, K, Mazzarella, L.
登録日2010-06-11
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An order-disorder transition plays a role in switching off the root effect in fish hemoglobins.
J.Biol.Chem., 285, 2010
4V19
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BU of 4v19 by Molmil
Structure of the large subunit of the mammalian mitoribosome, part 1 of 2
分子名称: MAGNESIUM ION, MITORIBOSOMAL 16S RRNA, MITORIBOSOMAL CP TRNA, ...
著者Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N.
登録日2014-09-25
公開日2014-10-08
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Nature, 515, 2014
4V51
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Structure of the Thermus thermophilus 70S ribosome complexed with mRNA, tRNA and paromomycin
分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Selmer, M, Dunham, C.M, Murphy, F.V, Weixlbaumer, A, Petry, S, Weir, J.R, Kelley, A.C, Ramakrishnan, V.
登録日2006-07-31
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the 70S ribosome complexed with mRNA and tRNA.
Science, 313, 2006
5W5J
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BU of 5w5j by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases
分子名称: N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION
著者Kreusch, A, Spraggon, G.
登録日2017-06-15
公開日2017-10-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
5W4K
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S.
登録日2017-06-12
公開日2017-08-30
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017

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