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8ZL9
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BU of 8zl9 by Molmil
ASFV p72 in complex with Fab G6
分子名称: B646L, G6 Heavy chain, G6 Light chain
著者Wang, X, Fu, W, Yu, Q.
登録日2024-05-17
公開日2024-09-18
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (4.36 Å)
主引用文献p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
8Y3O
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BU of 8y3o by Molmil
ASFV p72 in complex with Fab B1
分子名称: B646L, Heavy chain of B1, Light chain of B1
著者Wang, X, Fu, W, Yu, Q.
登録日2024-01-29
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
8Y3R
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BU of 8y3r by Molmil
ASFV p72 in complex with Fab H3
分子名称: B646L, Heavy chain of H3, Light chain of H3
著者Wang, X, Fu, W, Yu, Q.
登録日2024-01-29
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
8Y3P
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BU of 8y3p by Molmil
ASFV p72 in complex with Fab C9
分子名称: B646L, Heavy chain of C9, Light chain of C9
著者Wang, X, Fu, W, Yu, Q.
登録日2024-01-29
公開日2024-09-04
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献p72 antigenic mapping reveals a potential supersite of vulnerability for African swine fever virus.
Cell Discov, 10, 2024
5WTW
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BU of 5wtw by Molmil
Hepatitis B virus core protein Y132A mutant in P 41 21 2 Space Group
分子名称: CHLORIDE ION, Core protein
著者Zhou, Z, Xu, Z.H.
登録日2016-12-15
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
5WRE
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BU of 5wre by Molmil
Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01)
分子名称: (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2016-12-01
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
2L89
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BU of 2l89 by Molmil
Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
分子名称: PWWP domain-containing protein 1
著者Qiu, Y, Zhang, J, Zhang, W.
登録日2011-01-07
公開日2011-12-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA
Biochem.J., 2011
8GQ6
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BU of 8gq6 by Molmil
Cryo-EM Structure of the KBTBD2-CUL3-Rbx1 dimeric complex
分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ...
著者Sun, L, Chen, Z, Hu, Y, Mao, Q.
登録日2022-08-29
公開日2023-09-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2.
Nat.Struct.Mol.Biol., 31, 2024
6VBN
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BU of 6vbn by Molmil
Crystal Structure of hTDO2 bound to inhibitor GNE1
分子名称: 1,5-anhydro-2,3-dideoxy-3-[(5S)-5H-imidazo[5,1-a]isoindol-5-yl]-D-threo-pentitol, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase
著者Harris, S.F, Oh, A.
登録日2019-12-19
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors.
Acs Med.Chem.Lett., 11, 2020
6B2V
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BU of 6b2v by Molmil
Pyran synthase domain from module nine of the sorangicin pathway
分子名称: SorB
著者Wagner, D.T, Keatinge-Clay, A.T.
登録日2017-09-20
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural and Functional Studies of a Pyran Synthase Domain from a trans-Acyltransferase Assembly Line.
ACS Chem. Biol., 13, 2018
6CCA
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BU of 6cca by Molmil
Crystal structure of DszA carbon methyltransferase
分子名称: DisA protein
著者Meinke, J.L, Keatinge-Clay, A.T.
登録日2018-02-06
公開日2018-12-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Functional Studies of a gem-Dimethylating Methyltransferase from a trans-Acyltransferase Assembly Line.
ACS Chem. Biol., 13, 2018
3B5H
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BU of 3b5h by Molmil
Crystal structure of the extracellular portion of HAb18G/CD147
分子名称: ACETATE ION, Cervical EMMPRIN
著者Yu, X.-L, Chen, Z.-N.
登録日2007-10-26
公開日2008-05-06
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion.
J.Biol.Chem., 283, 2008
6J36
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BU of 6j36 by Molmil
crystal structure of Mycoplasma hyopneumoniae Enolase
分子名称: Enolase, GLYCEROL, SULFATE ION
著者Chen, R, Zhang, S, Gan, R, Xie, X, Feng, Z, Wang, W, Ran, T, Zhang, W, Xiang, Q, Shao, G.
登録日2019-01-04
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Featured Species-Specific Loops Are Found in the Crystal Structure ofMhpEno, a Cell Surface Adhesin FromMycoplasma hyopneumoniae.
Front Cell Infect Microbiol, 9, 2019
7YTX
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BU of 7ytx by Molmil
Crystal structure of TLR8 in complex with its antagonist
分子名称: (2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluoranylpyrrolidin-3-yl]-6-methyl-morpholine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shimizu, T, Sakaniwa, K.
登録日2022-08-16
公開日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A novel Toll-like receptor 7/8-specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus.
Eur.J.Pharmacol., 957, 2023
6KOE
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BU of 6koe by Molmil
X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis
分子名称: 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ...
著者Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J.
登録日2019-08-09
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KOC
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BU of 6koc by Molmil
X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis complexed with 3-iodo-N-oxo-2-heptyl-4-hydroxyquinoline
分子名称: 2-heptyl-3-iodanyl-1-oxidanyl-quinolin-4-one, AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, ...
著者Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J.
登録日2019-08-09
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site.
Proc.Natl.Acad.Sci.USA, 117, 2020
6KOB
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BU of 6kob by Molmil
X-ray Structure of the proton-pumping cytochrome aa3-600 menaquinol oxidase from Bacillus subtilis
分子名称: AA3-600 quinol oxidase subunit I, AA3-600 quinol oxidase subunit IIII, AA3-600 quinol oxidase subunit IV,Quinol oxidase subunit 4, ...
著者Xu, J, Ding, Z, Liu, B, Li, J, Gennis, R.B, Zhu, J.
登録日2019-08-09
公開日2020-01-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the cytochromeaa3-600 heme-copper menaquinol oxidase bound to inhibitor HQNO shows TM0 is part of the quinol binding site.
Proc.Natl.Acad.Sci.USA, 117, 2020
5YOF
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BU of 5yof by Molmil
Crystal structure of zika virus NS3 protease in complex with a dipeptide inhibitor
分子名称: (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, NS2B cofactor, NS3 Protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
5YB1
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BU of 5yb1 by Molmil
Structure and function of human serum albumin-metal agent complex
分子名称: PALMITIC ACID, Serum albumin, ~{N},~{N},12-trimethyl-3$l^{3}-thia-1$l^{4},5,6$l^{4}-triaza-2$l^{3}-cupratricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,6,9,11-pentaen-4-amine
著者Yang, F, Wang, T, Wang, J, Gou, Y, Zhang, Z.L.
登録日2017-09-02
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.616 Å)
主引用文献Developing an Anticancer Copper(II) Multitarget Pro-Drug Based on the His146 Residue in the IB Subdomain of Modified Human Serum Albumin.
Mol. Pharm., 15, 2018
5YOD
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BU of 5yod by Molmil
Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
分子名称: BENZOIC ACID, NS2B cofactor, NS3 protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
6KN5
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BU of 6kn5 by Molmil
Crystal structure of AFF4 C-terminal domain
分子名称: AF4/FMR2 family member 4
著者Chen, L.J, Yang, W.S, Xu, R.M.
登録日2019-08-03
公開日2020-07-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha.
Commun Biol, 3, 2020
6L8V
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BU of 6l8v by Molmil
membrane-bound Bax helix2-helix5 domain
分子名称: Apoptosis regulator BAX
著者OuYang, B, Lv, F.
登録日2019-11-07
公開日2020-11-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial membrane.
Embo J., 40, 2021
5GI4
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BU of 5gi4 by Molmil
DEAD-box RNA helicase
分子名称: ATP-dependent RNA helicase DeaD
著者Xu, L, Wang, L, Li, F, Wu, L, Shi, Y.
登録日2016-06-22
公開日2017-05-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.244 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
5GJU
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BU of 5gju by Molmil
DEAD-box RNA helicase
分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD
著者Xu, L, Li, F, Wang, L, Shi, Y.
登録日2016-07-02
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
7PFN
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BU of 7pfn by Molmil
Crystal Structure of a Class D Carbapenemase_K73ALY Complexed with Imipenem
分子名称: 1-BUTANOL, Beta-lactamase, Imipenem, ...
著者Zhou, Q, He, Y, Jin, Y.
登録日2021-08-11
公開日2022-08-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity
Acs Cent.Sci., 2023

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