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1R5T
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The Crystal Structure of Cytidine Deaminase CDD1, an Orphan C to U editase from Yeast
分子名称: Cytidine deaminase, ZINC ION
著者Xie, K, Sowden, M.P, Dance, G.S.C, Torelli, A.T, Smith, H.C, Wedekind, J.E.
登録日2003-10-13
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1.
Proc.Natl.Acad.Sci.Usa, 101, 2004
4QWP
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BU of 4qwp by Molmil
co-crystal structure of chitosanase OU01 with substrate
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Lyu, Q, Liu, W, Han, B.
登録日2014-07-17
公開日2015-07-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and biochemical insights into the degradation mechanism of chitosan by chitosanase OU01.
Biochim.Biophys.Acta, 1850, 2015
4R4B
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BU of 4r4b by Molmil
Crystal structure of the anti-hiv-1 antibody 2.2c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 2.2C HEAVY CHAIN, FAB 2.2C LIGHT CHAIN, ...
著者McLellan, J.S, Acharya, P, Huang, C.-C, Robinson, J, Kwong, P.D.
登録日2014-08-19
公開日2014-09-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4H
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BU of 4r4h by Molmil
Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ...
著者Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D.
登録日2014-08-19
公開日2014-09-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.28 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
4R4N
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BU of 4r4n by Molmil
Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ...
著者Acharya, P, Louder, R, Kwong, P.D.
登録日2014-08-19
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.56 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
5JO5
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BU of 5jo5 by Molmil
Crystal structure of 10E8 gHV-gLV antigen-binding fragment.
分子名称: 10E8 gHV, 10E8 gLV
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-02
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
5JR1
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BU of 5jr1 by Molmil
Crystal structure of 10E8 gHV-matureL antigen-binding fragment.
分子名称: 10E8 heavy chain, 10E8 mature light chain, ZINC ION
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-05
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
7VSW
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BU of 7vsw by Molmil
Crystal structure of a Fab-like fragment of anti-mesothelin antibody
分子名称: heavy chain, light chain
著者Yang, Z, Ying, T.
登録日2021-10-27
公開日2021-12-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use.
Small Methods, 6, 2022
7VSU
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BU of 7vsu by Molmil
Crystal structure of Fab fragment of anti-mesothelin antibody
分子名称: Light chain, heavy chain
著者Yang, Z, Ying, T.
登録日2021-10-27
公開日2021-12-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use.
Small Methods, 6, 2022
6IYN
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BU of 6iyn by Molmil
Solution structure of camelid nanobody Nb26 against aflatoxin B1
分子名称: Nb26
著者Nie, Y, He, T, Zhu, J, Li, S.L, Hu, R, Yang, Y.H.
登録日2018-12-17
公開日2019-01-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Chemical shift assignments of a camelid nanobody against aflatoxin B1.
Biomol NMR Assign, 13, 2019
4JZZ
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BU of 4jzz by Molmil
Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in C2221 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, CITRATE ANION, ...
著者Acharya, P, Kwong, P.D.
登録日2013-04-03
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
4JZW
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BU of 4jzw by Molmil
Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in P212121 space group
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, ...
著者Acharya, P, Kwong, P.D.
登録日2013-04-03
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.784 Å)
主引用文献Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
5E9E
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BU of 5e9e by Molmil
Crystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with AMP-PNP
分子名称: Myosin-II heavy chain kinase A, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Ye, Q, Jia, Z.
登録日2015-10-15
公開日2016-06-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation.
Sci Rep, 6, 2016
8HUG
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BU of 8hug by Molmil
F1 in complex with CRM1-Ran-RanBP1
分子名称: 4-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(3-fluorophenyl)sulfonylamino]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ...
著者Sun, Q, Lei, Y.
登録日2022-12-23
公開日2023-12-27
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.
J.Med.Chem., 66, 2023
8HUF
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BU of 8huf by Molmil
B28 in complex with CRM1-Ran-RanBP1
分子名称: 3-[(4-chlorophenyl)carbonylamino]-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]benzoic acid, BROMIDE ION, CHLORIDE ION, ...
著者Sun, Q, Lei, Y.
登録日2022-12-23
公開日2023-12-27
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.
J.Med.Chem., 66, 2023
5JNY
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BU of 5jny by Molmil
Crystal Structure of 10E8 Fab
分子名称: 10E8 Heavy Chain, 10E8 Light Chain, CHLORIDE ION, ...
著者Ofek, G, Kwong, P.
登録日2016-05-01
公開日2016-07-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.041 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
5JOF
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BU of 5jof by Molmil
Crystal structure of VRC03 gHVgLV antigen-binding fragment.
分子名称: SULFATE ION, VRC03 gHV heavy chain, VRC03 gLV light chain
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-02
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.208 Å)
主引用文献Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Structure, 24, 2016
5JXA
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BU of 5jxa by Molmil
Crystal structure of ligand-free VRC03 antigen-binding fragment.
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, PHOSPHATE ION, ...
著者Zhou, T, Moquin, S, Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-12
公開日2016-07-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Structure, 24, 2016
5E4H
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BU of 5e4h by Molmil
Crystal Structure of Apoenzyme Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A
分子名称: Myosin-II heavy chain kinase A, ZINC ION
著者Ye, Q, Cote, G.P, Jia, Z.
登録日2015-10-06
公開日2016-06-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation.
Sci Rep, 6, 2016
5LN3
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BU of 5ln3 by Molmil
The human 26S Proteasome at 6.8 Ang.
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P.
登録日2016-08-03
公開日2017-03-22
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome.
Mol. Cell Proteomics, 16, 2017
4K0A
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BU of 4k0a by Molmil
Crystal structure of CD4-mimetic miniprotein M48U7 in complex with HIV-1 YU2 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U7, CITRATE ANION, ...
著者Acharya, P, Kwong, P.D.
登録日2013-04-03
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
4H8W
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BU of 4h8w by Molmil
Crystal structure of non-neutralizing and ADCC-potent antibody N5-i5 in complex with HIV-1 clade A/E gp120 and sCD4.
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC AND NON-NEUTRALIZING ANTI-HIV-1 ANTIBODY N5-I5, ...
著者Tolbert, W.D, Acharya, P, Kwong, P.D, Pazgier, M.
登録日2012-09-24
公開日2014-04-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
3K6G
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BU of 3k6g by Molmil
Crystal structure of Rap1 and TRF2 complex
分子名称: Telomeric repeat-binding factor 2, Telomeric repeat-binding factor 2-interacting protein 1
著者Chen, Y, Rai, R, Yang, Y.T, Zheng, H, Chang, S, Lei, M.
登録日2009-10-08
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
7XJ2
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Structure of human TRPV3_G573S in complex with Trpvicin in C4 symmetry
分子名称: Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide
著者Fan, J, Yue, Z, Jiang, D, Lei, X.
登録日2022-04-14
公開日2022-11-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structural basis of TRPV3 inhibition by an antagonist.
Nat.Chem.Biol., 19, 2023
7XJ1
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Structure of human TRPV3_G573S in complex with Trpvicin in C2 symmetry
分子名称: Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者Fan, J, Yue, Z, Jiang, D, Lei, X.
登録日2022-04-14
公開日2022-11-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis of TRPV3 inhibition by an antagonist.
Nat.Chem.Biol., 19, 2023

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