5JXA

Crystal structure of ligand-free VRC03 antigen-binding fragment.

Summary for 5JXA

Entry DOI	10.2210/pdb5jxa/pdb
Descriptor	VRC03 Heavy chain, VRC03 Light chain, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	hiv-1, cd4 binding site, neutralizing, antibody development, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	49259.15
Authors	Zhou, T.,Moquin, S.,Joyce, M.G.,Mascola, J.R.,Kwong, P.D. (deposition date: 2016-05-12, release date: 2016-07-27, Last modification date: 2023-09-27)
Primary citation	Davenport, T.M.,Gorman, J.,Joyce, M.G.,Zhou, T.,Soto, C.,Guttman, M.,Moquin, S.,Yang, Y.,Zhang, B.,Doria-Rose, N.A.,Hu, S.L.,Mascola, J.R.,Kwong, P.D.,Lee, K.K. Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies. Structure, 24:1346-1357, 2016 Cited by PubMed: 27477385 DOI: 10.1016/j.str.2016.06.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation