4QWP

co-crystal structure of chitosanase OU01 with substrate

Summary for 4QWP

• Entry DOI: 10.2210/pdb4qwp/pdb
• Related: 4olt
• Descriptor: Chitosanase, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: chitosan, glycoside hydrolase, chitosanase ou01, chito-oligomer, hydrolysis, hydrolase
• Biological source: Pseudomonas sp. A-01
• Total number of polymer chains: 2
• Total formula weight: 55119.24

Authors

Lyu, Q.,Liu, W.,Han, B. (deposition date: 2014-07-17, release date: 2015-07-22, Last modification date: 2023-09-20)

Primary citation

Lyu, Q.,Shi, Y.,Wang, S.,Yang, Y.,Han, B.,Liu, W.,Jones, D.N.,Liu, W.
Structural and biochemical insights into the degradation mechanism of chitosan by chitosanase OU01.
Biochim.Biophys.Acta, 1850:1953-1961, 2015

PubMed Abstract: A detailed knowledge about the degradation mechanism of chitosanase hydrolysis is critical for the design of novel enzymes to produce well-defined chito-oligosaccharide products.

PubMed: 26145578
DOI: 10.1016/j.bbagen.2015.06.011

Experimental method

X-RAY DIFFRACTION (1.7 Å)