4R4B

Crystal structure of the anti-hiv-1 antibody 2.2c

Summary for 4R4B

• Entry DOI: 10.2210/pdb4r4b/pdb
• Related: 4R4F 4R4H 4R4N
• Descriptor: FAB 2.2C LIGHT CHAIN, FAB 2.2C HEAVY CHAIN, SULFATE ION, ... (5 entities in total)
• Functional Keywords: igg, fab, hiv, immunoglobulin domain, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 190812.22

Authors

McLellan, J.S.,Acharya, P.,Huang, C.-C.,Robinson, J.,Kwong, P.D. (deposition date: 2014-08-19, release date: 2014-09-10, Last modification date: 2024-01-10)

• Primary citation: Acharya, P.,Tolbert, W.D.,Gohain, N.,Wu, X.,Yu, L.,Liu, T.,Huang, W.,Huang, C.C.,Kwon, Y.D.,Louder, R.K.,Luongo, T.S.,McLellan, J.S.,Pancera, M.,Yang, Y.,Zhang, B.,Flinko, R.,Foulke, J.S.,Sajadi, M.M.,Kamin-Lewis, R.,Robinson, J.E.,Martin, L.,Kwong, P.D.,Guan, Y.,DeVico, A.L.,Lewis, G.K.,Pazgier, M.; Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.; J.Virol., 88:12895-12906, 2014; PubMed: 25165110; DOI: 10.1128/JVI.02194-14

Experimental method

X-RAY DIFFRACTION (2.199 Å)