8GJL
 
 | | multi-drug efflux pump RE-CmeB bound with Ciprofloxacin | | 分子名称: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Efflux pump membrane transporter | | 著者 | Zhang, Z. | | 登録日 | 2023-03-16 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
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8GJJ
 | | Multi-drug efflux pump RE-CmeB Apo form | | 分子名称: | Efflux pump membrane transporter | | 著者 | Zhang, Z. | | 登録日 | 2023-03-15 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
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4NNI
 | | Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide | | 分子名称: | 30S ribosomal protein S1, PYRAZINE-2-CARBOXYLIC ACID | | 著者 | Yang, J, Liu, Y, Cai, Q, Lin, D. | | 登録日 | 2013-11-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
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8GK4
 | | Multi-drug efflux pump RE-CmeB bound with Chloramphenicol | | 分子名称: | CHLORAMPHENICOL, Efflux pump membrane transporter | | 著者 | Zhang, Z. | | 登録日 | 2023-03-17 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
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8GK0
 | | Multi-drug efflux pump RE-CmeB bound with Erythromycin | | 分子名称: | ERYTHROMYCIN A, Efflux pump membrane transporter | | 著者 | Zhang, Z. | | 登録日 | 2023-03-16 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
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4NNK
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3QU8
 | | Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine. | | 分子名称: | 4-(4-nitrobenzyl)pyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | | 著者 | Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. | | 登録日 | 2011-02-23 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains.
Mol.Pharmacol., 80, 2011
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4NNH
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7V50
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7V4X
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7V51
 | | BVMO_negative mutant D432V | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative flavin-binding monooxygenase | | 著者 | Wu, Y, Yu, H.-L. | | 登録日 | 2021-08-16 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Precise regulation of the substrate selectivity of Baeyer-Villiger monooxygenase to minimize overoxidation of prazole sulfoxides.
CHINESE J CATAL, 51, 2023
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8I60
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3QOA
 | | Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine. | | 分子名称: | 4-benzylpyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | | 著者 | Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. | | 登録日 | 2011-02-09 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains.
Mol.Pharmacol., 80, 2011
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7JUN
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8IJK
 | | human KCNQ2-CaM-Ebio1 complex in the presence of PIP2 | | 分子名称: | Calmodulin-1, N-(1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | | 著者 | Ma, D, Guo, J. | | 登録日 | 2023-02-27 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Nat.Chem.Biol., 20, 2024
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7CZ6
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7D0L
 | | The major capsid of Omono River virus (strain:LZ), protrusion-free status. | | 分子名称: | Capsid protein | | 著者 | Shao, Q, Jia, X, Gao, Y, Liu, Z. | | 登録日 | 2020-09-11 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission.
Plos Pathog., 17, 2021
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7D0K
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8X43
 | | human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2 | | 分子名称: | Calmodulin-1, N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | | 著者 | Ma, D, Guo, J. | | 登録日 | 2023-11-15 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Nat.Chem.Biol., 20, 2024
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3UAS
 | | Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene | | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Gay, S.C, Zhang, H, Shah, M.B, Stout, C.D, Halpert, J.R, Hollenberg, P.F. | | 登録日 | 2011-10-21 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.939 Å) | | 主引用文献 | Potent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 Catalysis.
Biochemistry, 52, 2013
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4NNG
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4RAZ
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3HGG
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7VS4
 | | Crystal structure of PacII_M1M2S-DNA(m6A)-SAH complex | | 分子名称: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | | 著者 | Zhu, J, Gao, P. | | 登録日 | 2021-10-25 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems.
Nat Commun, 13, 2022
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7VRU
 | | Crystal structure of PacII_M1M2S-DNA-SAH complex | | 分子名称: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | | 著者 | Zhu, J, Gao, P. | | 登録日 | 2021-10-25 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems.
Nat Commun, 13, 2022
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