8GJL
multi-drug efflux pump RE-CmeB bound with Ciprofloxacin
Summary for 8GJL
| Entry DOI | 10.2210/pdb8gjl/pdb |
| EMDB information | 40093 |
| Descriptor | Efflux pump membrane transporter, 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID (2 entities in total) |
| Functional Keywords | efflux pump, membrane protein |
| Biological source | Campylobacter jejuni |
| Total number of polymer chains | 3 |
| Total formula weight | 342698.77 |
| Authors | Zhang, Z. (deposition date: 2023-03-16, release date: 2023-05-31, Last modification date: 2023-10-04) |
| Primary citation | Zhang, Z.,Lizer, N.,Wu, Z.,Morgan, C.E.,Yan, Y.,Zhang, Q.,Yu, E.W. Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance. Microbiol Spectr, 11:e0119723-e0119723, 2023 Cited by PubMed: 37289051DOI: 10.1128/spectrum.01197-23 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.44 Å) |
Structure validation
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