5UFR
 
 | | Structure of RORgt bound to | | 分子名称: | (S)-[4-chloro-2-(dimethylamino)-3-phenylquinolin-6-yl](1-methyl-1H-imidazol-5-yl)(pyridin-4-yl)methanol, Nuclear receptor ROR-gamma | | 著者 | Spurlino, J, Abad, M. | | 登録日 | 2017-01-05 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.068 Å) | | 主引用文献 | Identification and structure activity relationships of quinoline tertiary alcohol modulators of ROR gamma t.
Bioorg. Med. Chem. Lett., 27, 2017
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1TFB
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3P0B
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7DE2
 | | iron and alpha-ketoglutarate-dependent endoperoxidase NvfI | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, NvfI, ... | | 著者 | Zhai, R, Mori, T, Abe, I. | | 登録日 | 2020-11-01 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular insights into the endoperoxide formation by Fe(II)/ alpha-KG-dependent oxygenase NvfI.
Nat Commun, 12, 2021
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5UP4
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6IUK
 | | Cryo-EM structure of Murine Norovirus capsid | | 分子名称: | Major capsid protein VP1 | | 著者 | Song, C, Miyazaki, N, Iwasaki, K, Katayama, K, Murata, K. | | 登録日 | 2018-11-28 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Dynamic rotation of the protruding domain enhances the infectivity of norovirus.
Plos Pathog., 16, 2020
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6JI1
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7NMZ
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7ENB
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7EMZ
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7XWA
 | | Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BA.4/5 variant spike protein in complex with its receptor ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Suzuki, T, Kimura, K, Hashiguchi, T. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | | 主引用文献 | Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.
Cell, 185, 2022
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5XPF
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5VA9
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5U3A
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5UV5
 | | Crystal Structure of a 2-Hydroxyisoquinoline-1,3-dione RNase H Active Site Inhibitor with Multiple Binding Modes to HIV Reverse Transcriptase | | 分子名称: | 7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... | | 著者 | Kirby, K.A, Sarafianos, S.G. | | 登録日 | 2017-02-19 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase.
Antimicrob. Agents Chemother., 61, 2017
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5WZY
 | | Crystal structure of the P2X4 receptor from zebrafish in the presence of CTP at 2.8 Angstroms | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, ... | | 著者 | Kasuya, G, Hattori, M, Nureki, O. | | 登録日 | 2017-01-19 | | 公開日 | 2017-04-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.799 Å) | | 主引用文献 | Structural insights into the nucleotide base specificity of P2X receptors
Sci Rep, 7, 2017
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5GW9
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5GMT
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3LH0
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3LM5
 | | Crystal Structure of human Serine/Threonine Kinase 17B (STK17B) in complex with Quercetin | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Serine/threonine-protein kinase 17B | | 著者 | Ugochukwu, E, Soundararajan, M, Rellos, P, Fedorov, O, Phillips, C, Wang, J, Hapka, E, Filippakopoulos, P, Chaikuad, A, Pike, A.C.W, Carpenter, L, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-01-29 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.
J.Med.Chem., 63, 2020
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3LGF
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3LGL
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3RM1
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2NLI
 | | Crystal Structure of the complex between L-lactate oxidase and a substrate analogue at 1.59 angstrom resolution | | 分子名称: | FLAVIN MONONUCLEOTIDE, HYDROGEN PEROXIDE, LACTIC ACID, ... | | 著者 | Furuichi, M, Suzuki, N, Balasundaresan, D, Yoshida, Y, Minagawa, H, Watanabe, Y, Kaneko, H, Waga, I, Kumar, P.K.R, Mizuno, H. | | 登録日 | 2006-10-20 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | X-ray structures of Aerococcus viridans lactate oxidase and its complex with D-lactate at pH 4.5 show an alpha-hydroxyacid oxidation mechanism
J.Mol.Biol., 378, 2008
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3RLZ
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