5U3A

Ultra High Resolution Crystal Structure of Human Pancreatic Alpha Amylase

Summary for 5U3A

• Entry DOI: 10.2210/pdb5u3a/pdb
• Related: 1CPU 4W93 4X9Y 5TD4
• Descriptor: Pancreatic alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: amylase, diabetes, obesity, glucosyl hydrolase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 56228.04

Authors

Caner, S.,Brayer, G.D. (deposition date: 2016-12-01, release date: 2017-12-06, Last modification date: 2022-04-27)

• Primary citation: Goldbach, L.,Vermeulen, B.J.A.,Caner, S.,Liu, M.,Tysoe, C.,van Gijzel, L.,Yoshisada, R.,Trellet, M.,van Ingen, H.,Brayer, G.D.,Bonvin, A.M.J.J.,Jongkees, S.A.K.; Folding Then Binding vs Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic alpha-Amylase.; Acs Chem.Biol., 14:1751-1759, 2019; PubMed: 31241898; DOI: 10.1021/acschembio.9b00290

Experimental method

X-RAY DIFFRACTION (0.95 Å)