3MI0
 
 | | Crystal Structure of Mycobacterium Tuberculosis Proteasome at 2.2 A | | 分子名称: | (2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-4-ethyl-3-hydroxy-3-methyl-5-oxopyrrolidine-2-carbaldehyde, DIMETHYLFORMAMIDE, Proteasome subunit alpha, ... | | 著者 | Li, D, Li, H. | | 登録日 | 2010-04-09 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
|
|
4N4H
 | | Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.1K36me3 | | 分子名称: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.1, ... | | 著者 | Li, Y, Ren, Y, Li, H. | | 登録日 | 2013-10-08 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
Nature, 508, 2014
|
|
6WPG
 | | Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins | | 分子名称: | 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4 | | 著者 | Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N. | | 登録日 | 2020-04-27 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.283 Å) | | 主引用文献 | Structural basis of salicylic acid perception by Arabidopsis NPR proteins.
Nature, 586, 2020
|
|
1DMJ
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 5,6-CYCLIC-TETRAHYDROPTERIDINE | | 分子名称: | 7-AMINO-3,3A,4,5-TETRAHYDRO-8H-2-OXA-5,6,8,9B-TETRAAZA-CYCLOPENTA[A]NAPHTHALENE-1,9-DIONE, ACETATE ION, CACODYLATE ION, ... | | 著者 | Kotsonis, P, Frohlich, L.G, Raman, C.S, Li, H, Berg, M, Gerwig, R, Groehn, V, Kang, Y, Al-Masoudi, N, Taghavi-Moghadam, S, Mohr, D, Munch, U, Schnabel, J, Martasek, P, Masters, B.S, Strobel, H, Poulos, T, Matter, H, Pfleiderer, W, Schmidt, H.H. | | 登録日 | 1999-12-14 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
|
|
2VQI
 | | Structure of the P pilus usher (PapC) translocation pore | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE USHER PROTEIN PAPC | | 著者 | Remaut, H, Tang, C, Henderson, N.S, Pinkner, J.S, Wang, T, Hultgren, S.J, Thanassi, D.G, Li, H, Waksman, G. | | 登録日 | 2008-03-16 | | 公開日 | 2008-05-27 | | 最終更新日 | 2019-01-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Fiber formation across the bacterial outer membrane by the chaperone/usher pathway.
Cell, 133, 2008
|
|
3DQS
 | | Structure of endothelial NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(4'-chlorobenzyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | | 著者 | Igarashi, J, Li, H, Poulos, T.L. | | 登録日 | 2008-07-09 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
J.Med.Chem., 52, 2009
|
|
1I83
 | | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE (H4B FREE) | | 分子名称: | ACETATE ION, GLYCEROL, N1,N14-BIS((S-METHYL)ISOTHIOUREIDO)TETRADECANE, ... | | 著者 | Raman, C.S, Li, H, Martasek, P, Babu, B.R, Griffith, O.W, Masters, B.S.S, Poulos, T.L. | | 登録日 | 2001-03-12 | | 公開日 | 2001-08-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
|
|
3DQR
 | | Structure of neuronal NOS D597N/M336V mutant heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6"-aminopyridin-2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3S,4S)-4-[(6-aminopyridin-2-yl)methyl]pyrrolidin-3-yl}ethane-1,2-diamine, ... | | 著者 | Igarashi, J, Li, H, Poulos, T.L. | | 登録日 | 2008-07-09 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
J.Med.Chem., 52, 2009
|
|
3DQT
 | | Structure of endothelial NOS heme domain in complex with a inhibitor (+-)-N1-{trans-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-chlorobenzyl)ethane-1,2-diamine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | | 著者 | Igarashi, J, Li, H, Poulos, T.L. | | 登録日 | 2008-07-09 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
J.Med.Chem., 52, 2009
|
|
3H6I
 | |
3H6F
 | |
3HFA
 | |
3HF9
 | |
1HQR
 | | CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II | | 分子名称: | HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ... | | 著者 | Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R. | | 登録日 | 2000-12-19 | | 公開日 | 2001-01-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
|
|
6MX6
 | | The Prp8 intein of Cryptococcus neoformans | | 分子名称: | Pre-mRNA-processing-splicing factor 8 | | 著者 | Li, Z, Li, H. | | 登録日 | 2018-10-30 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.
Plos Biol., 17, 2019
|
|
1RS8
 | | Bovine endothelial NOS heme domain with D-lysine-D-nitroarginine amide bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | | 著者 | Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L. | | 登録日 | 2003-12-09 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
|
|
8E1A
 | | Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors | | 分子名称: | 1,2-ETHANEDIOL, 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine, Androgen receptor | | 著者 | Lallous, N, Li, H, Radaeva, M, Dalal, K, Leblanc, E, Ban, F, Ciesielski, F, Chow, B, Morin, M, Singh, K, Rennie, P.S, Cherkasov, A. | | 登録日 | 2022-08-10 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors.
Cells, 11, 2022
|
|
1RS6
 | | Rat neuronal NOS heme domain with D-lysine-D-nitroarginine amide bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ... | | 著者 | Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L. | | 登録日 | 2003-12-09 | | 公開日 | 2004-05-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
|
|
6OWU
 | |
1RS9
 | | Bovine endothelial NOS heme domain with D-phenylalanine-D-nitroarginine amide bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | | 著者 | Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L. | | 登録日 | 2003-12-09 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
|
|
2NNW
 | | Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs | | 分子名称: | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein | | 著者 | Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H. | | 登録日 | 2006-10-24 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs.
J.Mol.Biol., 371, 2007
|
|
4QBS
 | |
1RS7
 | | Rat neuronal NOS heme domain with D-phenylalanine-D-nitroarginine amide bound | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ... | | 著者 | Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L. | | 登録日 | 2003-12-09 | | 公開日 | 2004-05-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
|
|
4HK4
 | | Crystal structure of apo Tyrosine-tRNA ligase mutant protein | | 分子名称: | DI(HYDROXYETHYL)ETHER, Tyrosine--tRNA ligase | | 著者 | Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J. | | 登録日 | 2012-10-15 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Crystal structure of apo Tyrosine-tRNA ligase mutant protein
To be Published
|
|
4HPW
 | | Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine | | 分子名称: | 3-methoxy-L-tyrosine, Tyrosine--tRNA ligase | | 著者 | Yu, Y, Zhou, Q, Dong, J, Li, J, Xiaoxuan, L, Mukherjee, A, Ouyang, H, Nilges, M, Li, H, Gao, F, Gong, W, Lu, Y, Wang, J. | | 登録日 | 2012-10-24 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
To be Published
|
|
