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5AO4
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BU of 5ao4 by Molmil
Crystal structure of in vitro phosphorylated human SAMHD1 (amino acid residues 115-626) bound to GTP
分子名称: DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, GUANOSINE-5'-TRIPHOSPHATE
著者Arnold, L.H, Schwefel, D, Taylor, I.A.
登録日2015-09-09
公開日2015-10-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
8PI1
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BU of 8pi1 by Molmil
Bicyclic INCYPRO Pseudomonas fluorescens esterase
分子名称: Arylesterase, GLYCEROL, N-[2-[3,5-bis[2-(2-iodanylethanoylamino)ethanoyl]-1,3,5-triazinan-1-yl]-2-oxidanylidene-ethyl]-2-iodanyl-ethanamide
著者Kiehstaller, S, Pearce, N.M, Grossmann, T.N, Hennig, S.
登録日2023-06-20
公開日2023-11-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Covalent bicyclization of protein complexes yields durable quaternary structures.
Chem, 10, 2024
7AH3
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BU of 7ah3 by Molmil
Kinase domain of cSrc in complex with a pyrazolopyrimidine
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Dello Iacono, L, Kleinboelting, S, Fallacara, A.L, Rauh, D.
登録日2020-09-24
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Insights into the binding of pyrazolopyrimidines to Src kinase
To Be Published
1ZXJ
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BU of 1zxj by Molmil
Crystal structure of the hypthetical Mycoplasma protein, MPN555
分子名称: Hypothetical protein MG377 homolog
著者Schulze-Gahmen, U, Aono, S, Shengfeng, C, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2005-06-08
公開日2005-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function.
Acta Crystallogr.,Sect.D, 61, 2005
3JVF
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BU of 3jvf by Molmil
Crystal structure of an Interleukin-17 receptor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ely, L.K, Garcia, K.C.
登録日2009-09-16
公開日2009-10-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of receptor sharing by interleukin 17 cytokines.
Nat.Immunol., 10, 2009
7E24
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BU of 7e24 by Molmil
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase
著者Chen, L, Tang, J, Yuan, S.
登録日2021-02-04
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7203 Å)
主引用文献Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
7E28
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BU of 7e28 by Molmil
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
分子名称: Oxidoreductase
著者Chen, L, Tang, J, Yuan, S.
登録日2021-02-05
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
8OWZ
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BU of 8owz by Molmil
Crystal structure of human Sirt2 in complex with a triazole-based SirReal
分子名称: (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[5-[[3-[[1-(2-methoxyethyl)-1,2,3-triazol-4-yl]methoxy]phenyl]methyl]-1,3-thiazol-2-yl]ethanamide, ...
著者Friedrich, F, Zhang, L, Schiedel, M, Einsle, O, Jung, M.
登録日2023-04-28
公開日2023-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
J.Med.Chem., 66, 2023
6FIB
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BU of 6fib by Molmil
Structure of human 4-1BB ligand
分子名称: Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor ligand superfamily member 9,4-1BBL -CH/CL fusion, Tumor necrosis factor ligand superfamily member 9,Uncharacterized protein
著者Joseph, C, Claus, C, Ferrara, C, von Hirschheydt, T, Prince, C, Funk, D, Klein, C, Benz, J.
登録日2018-01-17
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.
Sci Transl Med, 11, 2019
7RX2
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BU of 7rx2 by Molmil
afTMEM16 in C22 lipid nanodiscs with MSP1E3 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXA
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BU of 7rxa by Molmil
afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXB
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BU of 7rxb by Molmil
afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Feng, Z, Accardi, A.
登録日2021-08-22
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXH
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BU of 7rxh by Molmil
afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, monomer with extra lipids
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-23
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RX3
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BU of 7rx3 by Molmil
afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-21
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXG
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BU of 7rxg by Molmil
afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, full dimer
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
著者Falzone, M.E, Accardi, A.
登録日2021-08-23
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.28 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RWJ
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afTMEM16 in C22 lipid nanodiscs with MSP2N2 scaffold protein in the presnece of Ca2+
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Plasma membrane channel protein (Aqy1), ...
著者Falzone, M.E, Accardi, A.
登録日2021-08-20
公開日2022-05-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
6PC1
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BU of 6pc1 by Molmil
Crystal structure of Helicobacter pylori PPX/GppA (E143A) in complex with ppGpp
分子名称: (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, ...
著者Song, H, Wang, C, Shaw, G.X, Ji, X.
登録日2019-06-15
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori.
Febs J., 287, 2020
6PC0
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BU of 6pc0 by Molmil
Crystal structure of Helicobacter pylori PPX/GppA
分子名称: (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, D-MALATE, ...
著者Song, H, Wang, C, Shaw, G.X, Ji, X.
登録日2019-06-15
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori.
Febs J., 287, 2020
6PBZ
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BU of 6pbz by Molmil
Crystal structure of Escherichia coli GppA
分子名称: CHLORIDE ION, Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase
著者Song, H, Shaw, G.X, Wang, C, Ji, X.
登録日2019-06-15
公開日2019-11-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.475 Å)
主引用文献Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori.
Febs J., 287, 2020
8P9V
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BU of 8p9v by Molmil
Crystal Structure of Two-Domain Laccase mutant M199G/R240H/D268N from Streptomyces griseoflavus
分子名称: COPPER (II) ION, OXYGEN MOLECULE, PEROXIDE ION, ...
著者Kolyadenko, I.A, Tishchenko, S.V, Gabdulkhakov, A.G.
登録日2023-06-06
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insight into the Amino Acid Environment of the Two-Domain Laccase's Trinuclear Copper Cluster.
Int J Mol Sci, 24, 2023
8P9U
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BU of 8p9u by Molmil
Crystal Structure of Two-Domain Laccase mutant M199A/D268N from Streptomyces griseoflavus
分子名称: CALCIUM ION, COPPER (II) ION, OXYGEN MOLECULE, ...
著者Kolyadenko, I.A, Tishchenko, S.V, Gabdulkhakov, A.G.
登録日2023-06-06
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insight into the Amino Acid Environment of the Two-Domain Laccase's Trinuclear Copper Cluster.
Int J Mol Sci, 24, 2023
8OX0
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BU of 8ox0 by Molmil
Structure of apo telomeric nucleosome
分子名称: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ...
著者Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D.
登録日2023-04-28
公開日2023-08-30
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
8OX1
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Structure of TRF1core in complex with telomeric nucleosome
分子名称: Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ...
著者Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D.
登録日2023-04-28
公開日2023-08-30
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of telomeric nucleosome recognition by shelterin factor TRF1.
Sci Adv, 9, 2023
6VYD
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BU of 6vyd by Molmil
Terpenoid Cyclase FgGS in Complex with Mg, Inorganic Pyrophosphate, and Benzyltriethylammonium cation
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Herbst-Gervasoni, C.J, Christianson, D.W.
登録日2020-02-26
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases.
Nat Commun, 11, 2020
6W26
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BU of 6w26 by Molmil
Terpenoid Cyclase FgGS in Complex with Mg, Inorganic Pyrophosphate, and Imidazole
分子名称: 1,2-ETHANEDIOL, GLYCEROL, IMIDAZOLE, ...
著者Herbst-Gervasoni, C.J, Christianson, D.W.
登録日2020-03-05
公開日2020-07-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases.
Nat Commun, 11, 2020

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