2FGY
 
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4X6Y
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7FBR
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2ZXX
 | | Crystal structure of Cdt1/geminin complex | | 分子名称: | DNA replication factor Cdt1, Geminin | | 著者 | Cho, Y, Lee, C, Hong, B.S, Choi, J.M. | | 登録日 | 2009-01-08 | | 公開日 | 2009-02-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
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7FBV
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7CEE
 | | Crystal structure of mouse neuroligin-3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3 | | 著者 | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | | 登録日 | 2020-06-23 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.763 Å) | | 主引用文献 | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
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7CEG
 | | Crystal structure of the complex between mouse PTP delta and neuroligin-3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3 | | 著者 | Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. | | 登録日 | 2020-06-23 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
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2XSG
 | | Structure of the gh92 family glycosyl hydrolase ccman5 | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CCMAN5, ... | | 著者 | Baranova, E, Tiels, P, Remaut, H. | | 登録日 | 2010-09-29 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Bacterial Glycosidase Enables Mannose-6-Phosphate Modification and Improved Cellular Uptake of Yeast-Produced Recombinant Human Lysosomal Enzymes.
Nat.Biotechnol., 30, 2012
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2DXS
 | | Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor | | 分子名称: | Genome polyprotein, N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE | | 著者 | Adachi, T, Tsuruha, J, Doi, S, Murase, K, Ikegashira, K, Watanabe, S, Uehara, K, Orita, T, Nomura, A, Kamada, M. | | 登録日 | 2006-08-30 | | 公開日 | 2006-12-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors
J.Med.Chem., 49, 2006
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7E4D
 | | Crystal structure of PlDBR | | 分子名称: | Double Bond Reductase | | 著者 | Sugimoto, K, Senda, M, Senda, T. | | 登録日 | 2021-02-11 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Exploration and structure-based engineering of alkenal double bond reductases catalyzing the C alpha C beta double bond reduction of coniferaldehyde.
N Biotechnol, 68, 2022
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3ALY
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5L87
 | | Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | | 分子名称: | 1,2-ETHANEDIOL, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, Peroxin 14 | | 著者 | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | | 登録日 | 2016-06-07 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (0.87 Å) | | 主引用文献 | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
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5NYT
 | | M2 G-quadruplex 20 wt% ethylene glycol | | 分子名称: | DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') | | 著者 | Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N. | | 登録日 | 2017-05-11 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
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5NYS
 | | M2 G-quadruplex dilute solution | | 分子名称: | DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') | | 著者 | Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N. | | 登録日 | 2017-05-11 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
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5NYU
 | | M2 G-quadruplex 10 wt% PEG8000 | | 分子名称: | DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') | | 著者 | Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N. | | 登録日 | 2017-05-11 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
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4PF3
 | | Mineralocorticoid receptor ligand-binding domain with compuond 37a | | 分子名称: | 1,2-ETHANEDIOL, 6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor | | 著者 | Sogabe, S, Habuka, N. | | 登録日 | 2014-04-28 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists
Bioorg.Med.Chem., 22, 2014
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7BVR
 | | DgpB-DgpC complex apo | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AP_endonuc_2 domain-containing protein, DgpB, ... | | 著者 | Mori, T, He, H, Abe, I. | | 登録日 | 2020-04-11 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.
Nat Commun, 12, 2021
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5L8A
 | | Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | | 分子名称: | 1,2-ETHANEDIOL, 1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(phenylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, GLYCINE, ... | | 著者 | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | | 登録日 | 2016-06-07 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
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6R77
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5MMC
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8QKT
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5MT7
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5MT6
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6MBZ
 | | Structure of Transcription Factor | | 分子名称: | Signal transducer and activator of transcription 5B | | 著者 | Seo, H.-S, Dhe-Paganon, S. | | 登録日 | 2018-08-30 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Structural and functional consequences of the STAT5BN642Hdriver mutation.
Nat Commun, 10, 2019
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5MT8
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