2XSG

Structure of the gh92 family glycosyl hydrolase ccman5

Summary for 2XSG

Entry DOI	10.2210/pdb2xsg/pdb
Descriptor	CCMAN5, CALCIUM ION, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	hydrolase, mannosidase
Biological source	CELLULOSIMICROBIUM CELLULANS
Total number of polymer chains	2
Total formula weight	165556.72
Authors	Baranova, E.,Tiels, P.,Remaut, H. (deposition date: 2010-09-29, release date: 2011-10-12, Last modification date: 2013-02-06)
Primary citation	Tiels, P.,Baranova, E.,Piens, K.,De Visscher, C.,Pynaert, G.,Nerinckx, W.,Stout, J.,Fudalej, F.,Hulpiau, P.,Tannler, S.,Geysens, S.,Van Hecke, A.,Valevska, A.,Vervecken, W.,Remaut, H.,Callewaert, N. A Bacterial Glycosidase Enables Mannose-6-Phosphate Modification and Improved Cellular Uptake of Yeast-Produced Recombinant Human Lysosomal Enzymes. Nat.Biotechnol., 30:1225-, 2012 Cited by PubMed: 23159880 DOI: 10.1038/NBT.2427 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation