8KGQ
| Structure of African swine fever virus topoisomerase II in complex with dsDNA | 分子名称: | DNA (38-MER), DNA topoisomerase 2 | 著者 | Cong, J, Xin, Y, Li, X, Chen, Y. | 登録日 | 2023-08-19 | 公開日 | 2024-04-03 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structural insights into the DNA topoisomerase II of the African swine fever virus. Nat Commun, 15, 2024
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6LKH
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5K6G
| Crystal structure of prefusion-stabilized RSV F single-chain 9-24 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0,Fusion glycoprotein F0 | 著者 | Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-09-28 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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5K6B
| Crystal structure of prefusion-stabilized RSV F single-chain 9 DS-Cav1 variant. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, SULFATE ION | 著者 | Joyce, M.G, Zhang, B, Rundlet, E.J, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-31 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.981 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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7XWJ
| structure of patulin-detoxifying enzyme Y155F with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWI
| structure of patulin-detoxifying enzyme with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWH
| structure of patulin-detoxifying enzyme with NADP+ | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWL
| structure of patulin-detoxifying enzyme Y155F/V187F with NADPH | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWN
| structure of patulin-detoxifying enzyme Y155F/V187K with NADPH and substrate | 分子名称: | (4~{S})-4-oxidanyl-4,6-dihydrofuro[3,2-c]pyran-2-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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7XWK
| structure of patulin-detoxifying enzyme Y155F with NADPH and substrate | 分子名称: | (4~{S})-4-oxidanyl-4,6-dihydrofuro[3,2-c]pyran-2-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase | 著者 | Dai, L, Li, H, Hu, Y, Guo, R.T, Chen, C.C. | 登録日 | 2022-05-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin. Int.J.Biol.Macromol., 222, 2022
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5K6C
| Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0,Fusion glycoprotein F0, SULFATE ION | 著者 | Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-10-12 | 最終更新日 | 2016-10-19 | 実験手法 | X-RAY DIFFRACTION (3.576 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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5K6H
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5K6I
| Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C, S46G-E92D-S215P-K465Q variant. | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... | 著者 | Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-17 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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8HVS
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5K6F
| Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0 | 著者 | Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-10 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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6MAJ
| HBO1 is required for the maintenance of leukaemia stem cells | 分子名称: | 4-fluoro-N'-[(3-hydroxyphenyl)sulfonyl]-5-methyl[1,1'-biphenyl]-3-carbohydrazide, BRD1 protein, GLYCEROL, ... | 著者 | Ren, B, Peat, T.S, Monahan, B, Dawson, M, Street, I. | 登録日 | 2018-08-27 | 公開日 | 2019-12-25 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (2.139 Å) | 主引用文献 | HBO1 is required for the maintenance of leukaemia stem cells. Nature, 577, 2020
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6MAK
| HBO1 is required for the maintenance of leukaemia stem cells | 分子名称: | ACETYL COENZYME *A, BRD1 protein, Histone acetyltransferase KAT7, ... | 著者 | Ren, B, Peat, T.S, Monahan, B, Dawson, M, Street, I. | 登録日 | 2018-08-27 | 公開日 | 2019-12-25 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | HBO1 is required for the maintenance of leukaemia stem cells. Nature, 577, 2020
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8K0S
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6JE9
| Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers | 分子名称: | AcrIIC3, CRISPR-associated endonuclease Cas9, sgRNA | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | 登録日 | 2019-02-04 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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8K15
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8K0R
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8K0Q
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8K0P
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5CFF
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6JE4
| Crystal structure of Nme1Cas9-sgRNA-dsDNA dimer mediated by double protein inhibitor AcrIIC3 monomers | 分子名称: | 1,2-ETHANEDIOL, AcrIIC3, CRISPR-associated endonuclease Cas9, ... | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | 登録日 | 2019-02-04 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.069 Å) | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States. Mol.Cell, 76, 2019
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