4GZW
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![BU of 4gzw by Molmil](/molmil-images/mine/4gzw) | |
4HJS
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4HJU
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![BU of 4hju by Molmil](/molmil-images/mine/4hju) | |
4HJT
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![BU of 4hjt by Molmil](/molmil-images/mine/4hjt) | |
4HLZ
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4GZT
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![BU of 4gzt by Molmil](/molmil-images/mine/4gzt) | N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhu, X, Wilson, I.A. | 登録日 | 2012-09-06 | 公開日 | 2012-10-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4GZP
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![BU of 4gzp by Molmil](/molmil-images/mine/4gzp) | N2 Neuraminidase of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhu, X, Wilson, I.A. | 登録日 | 2012-09-06 | 公開日 | 2012-10-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4FNK
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4FQK
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![BU of 4fqk by Molmil](/molmil-images/mine/4fqk) | Influenza B/Brisbane/60/2008 hemagglutinin Fab CR8059 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8059 Heavy Chain, ... | 著者 | Dreyfus, C, Laursen, N.S, Wilson, I.A. | 登録日 | 2012-06-25 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (5.65 Å) | 主引用文献 | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FI6
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![BU of 4fi6 by Molmil](/molmil-images/mine/4fi6) | Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | 分子名称: | 3-[5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin | 著者 | Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W. | 登録日 | 2012-06-08 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate. J.Am.Chem.Soc., 135, 2013
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4FQH
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![BU of 4fqh by Molmil](/molmil-images/mine/4fqh) | Crystal Structure of Fab CR9114 | 分子名称: | 1,2-ETHANEDIOL, NITRATE ION, antibody CR9114 heavy chain, ... | 著者 | Dreyfus, C, Wilson, I.A. | 登録日 | 2012-06-25 | 公開日 | 2012-08-22 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FI8
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![BU of 4fi8 by Molmil](/molmil-images/mine/4fi8) | Kinetic Stabilization of transthyretin through covalent modification of K15 by 4-bromo-3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | 分子名称: | 4-bromo-3-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin | 著者 | Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W. | 登録日 | 2012-06-08 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate. J.Am.Chem.Soc., 135, 2013
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4GXX
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4GZO
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![BU of 4gzo by Molmil](/molmil-images/mine/4gzo) | |
4GZX
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4GZS
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![BU of 4gzs by Molmil](/molmil-images/mine/4gzs) | N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Zhu, X, Wilson, I.A. | 登録日 | 2012-09-06 | 公開日 | 2012-10-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
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4FP8
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4FI7
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![BU of 4fi7 by Molmil](/molmil-images/mine/4fi7) | Kinetic Stabilization of transthyretin through covalent modification of K15 by 3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)-benzenesulfonamide | 分子名称: | 3-[5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzenesulfonyl fluoride, Transthyretin | 著者 | Connelly, S, Grimster, N, Wilson, I.A, Kelly, J.W. | 登録日 | 2012-06-08 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.402 Å) | 主引用文献 | Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate. J.Am.Chem.Soc., 135, 2013
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4FQJ
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![BU of 4fqj by Molmil](/molmil-images/mine/4fqj) | Influenza B/Florida/4/2006 hemagglutinin Fab CR8071 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, antibody CR8071 heavy chain, ... | 著者 | Dreyfus, C, Laursen, N.S, Wilson, I.A. | 登録日 | 2012-06-25 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FQY
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![BU of 4fqy by Molmil](/molmil-images/mine/4fqy) | Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin | 分子名称: | Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ... | 著者 | Ekiert, D.C, Dreyfus, C, Wilson, I.A. | 登録日 | 2012-06-25 | 公開日 | 2012-08-22 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (5.253 Å) | 主引用文献 | Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
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4FQI
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4GXV
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4I78
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4GMT
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![BU of 4gmt by Molmil](/molmil-images/mine/4gmt) | Crystal structure of heterosubtypic Fab S139/1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ... | 著者 | Lee, P.S, Ekiert, D.C, Wilson, I.A. | 登録日 | 2012-08-16 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity. Proc.Natl.Acad.Sci.USA, 109, 2012
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4GHA
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![BU of 4gha by Molmil](/molmil-images/mine/4gha) | Crystal structure of Marburg virus VP35 RNA binding domain bound to 12-bp dsRNA | 分子名称: | Polymerase cofactor VP35, RNA (5'-R(*CP*UP*AP*GP*AP*CP*GP*UP*CP*UP*AP*G)-3') | 著者 | Bale, S, Jean-Philippe, J, Bornholdt, Z.A, Kimberlin, C.K, Halfmann, P, Zandonatti, M.A, Kunert, J, Kroon, G.J.A, Kawaoka, Y, MacRae, I.J, Wilson, I.A, Saphire, E.O. | 登録日 | 2012-08-07 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. Plos Pathog., 8, 2012
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