4FQH

Crystal Structure of Fab CR9114

Summary for 4FQH

• Entry DOI: 10.2210/pdb4fqh/pdb
• Related: 4FNK 4FQI 4FQJ 4FQK 4FQL 4FQM 4FQV 4FQY
• Descriptor: antibody CR9114 heavy chain, antibody CR9114 light chain, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: neutralizing antibodies, antibody affinity, antigens, epitope, glycosylation, hemagglutinin glycoproteins, immunoglobulin fab fragment, influenza virus, influenza vaccines, membrane fusion, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 95085.21

Authors

Dreyfus, C.,Wilson, I.A. (deposition date: 2012-06-25, release date: 2012-08-22, Last modification date: 2018-01-31)

• Primary citation: Dreyfus, C.,Laursen, N.S.,Kwaks, T.,Zuijdgeest, D.,Khayat, R.,Ekiert, D.C.,Lee, J.H.,Metlagel, Z.,Bujny, M.V.,Jongeneelen, M.,van der Vlugt, R.,Lamrani, M.,Korse, H.J.,Geelen, E.,Sahin, O.,Sieuwerts, M.,Brakenhoff, J.P.,Vogels, R.,Li, O.T.,Poon, L.L.,Peiris, M.,Koudstaal, W.,Ward, A.B.,Wilson, I.A.,Goudsmit, J.,Friesen, R.H.; Highly conserved protective epitopes on influenza B viruses.; Science, 337:1343-1348, 2012; PubMed: 22878502; DOI: 10.1126/science.1222908

Experimental method

X-RAY DIFFRACTION (2.05 Å)