5UJ4
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![BU of 5uj4 by Molmil](/molmil-images/mine/5uj4) | Crystal structure of the KPC-2 beta-lactamase complexed with hydrolyzed faropenem | 分子名称: | (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL | 著者 | Pemberton, O.A, Chen, Y. | 登録日 | 2017-01-16 | 公開日 | 2017-04-26 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2). J. Med. Chem., 60, 2017
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5UM6
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![BU of 5um6 by Molmil](/molmil-images/mine/5um6) | Crystal Structure of S. pombe Uba1 in a closed conformation | 分子名称: | 2-(decylamino)ethane-1-thiol, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, SULFATE ION, ... | 著者 | Lv, Z, Yuan, L, Aldana-Masangkay, G, Atkison, J.H, Chen, Y, Olsen, S.K. | 登録日 | 2017-01-26 | 公開日 | 2017-06-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Domain alternation and active site remodeling are conserved structural features of ubiquitin E1. J. Biol. Chem., 292, 2017
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6IF8
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![BU of 6if8 by Molmil](/molmil-images/mine/6if8) | Aeromonas hydrophila MtaN-2 complexed with adenine | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | 著者 | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | 登録日 | 2018-09-18 | 公開日 | 2018-10-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Aeromonas hydrophila MtaN-2 complexed with adenine To Be Published
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5UJO
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5UL8
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6K2Q
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![BU of 6k2q by Molmil](/molmil-images/mine/6k2q) | Aeromonas hydrophila MtaN-2 complexed with adenine | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | 著者 | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | 登録日 | 2019-05-15 | 公開日 | 2019-05-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Aeromonas hydrophila Cytoplasmic 5'-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase. Biochemistry, 58, 2019
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5UJ3
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![BU of 5uj3 by Molmil](/molmil-images/mine/5uj3) | Crystal structure of the KPC-2 beta-lactamase complexed with hydrolyzed cefotaxime | 分子名称: | (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL | 著者 | Pemberton, O.A, Chen, Y. | 登録日 | 2017-01-16 | 公開日 | 2017-04-26 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Molecular Basis of Substrate Recognition and Product Release by the Klebsiella pneumoniae Carbapenemase (KPC-2). J. Med. Chem., 60, 2017
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3R1G
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![BU of 3r1g by Molmil](/molmil-images/mine/3r1g) | Structure Basis of Allosteric Inhibition of BACE1 by an Exosite-Binding Antibody | 分子名称: | Beta-secretase 1, FAB of YW412.8.31 antibody heavy chain, FAB of YW412.8.31 antibody light chain | 著者 | Wang, W, Rouge, L, Wu, P, Chiu, C, Chen, Y, Wu, Y, Watts, R.J. | 登録日 | 2011-03-10 | 公開日 | 2011-06-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-{beta} Production in Vivo. Sci Transl Med, 3, 2011
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6L6Q
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6J07
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![BU of 6j07 by Molmil](/molmil-images/mine/6j07) | Crystal structure of human TERB2 and TERB1 | 分子名称: | Telomere repeats-binding bouquet formation protein 1, Telomere repeats-binding bouquet formation protein 2, ZINC ION | 著者 | Wang, Y, Chen, Y, Wu, J, Huang, C, Lei, M. | 登録日 | 2018-12-21 | 公開日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (3.298 Å) | 主引用文献 | The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. Nat Commun, 10, 2019
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6J08
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![BU of 6j08 by Molmil](/molmil-images/mine/6j08) | Crystal structure of human MAJIN and TERB2 | 分子名称: | Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2 | 著者 | Wang, Y, Chen, Y, Wu, J, Huang, C, Lei, M. | 登録日 | 2018-12-21 | 公開日 | 2019-02-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. Nat Commun, 10, 2019
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6JPE
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![BU of 6jpe by Molmil](/molmil-images/mine/6jpe) | Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1 | 分子名称: | Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION | 著者 | Chen, X, Dai, S, Zhou, Z, Chen, Y. | 登録日 | 2019-03-26 | 公開日 | 2020-05-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma. J.Med.Chem., 63, 2020
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6K63
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![BU of 6k63 by Molmil](/molmil-images/mine/6k63) | The crystal structure of cytidine deaminase from Klebsiella pneumoniae | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Cytidine deaminase, ZINC ION | 著者 | Liu, W, Shang, F, Lan, J, Chen, Y, Wang, L, Xu, Y. | 登録日 | 2019-06-01 | 公開日 | 2019-07-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.073 Å) | 主引用文献 | Biochemical and structural analysis of the Klebsiella pneumoniae cytidine deaminase CDA. Biochem.Biophys.Res.Commun., 519, 2019
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2QPE
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![BU of 2qpe by Molmil](/molmil-images/mine/2qpe) | An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus | 分子名称: | COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, Cytochrome c oxidase subunit 1, ... | 著者 | Liu, B, Luna, V.M, Chen, Y, Stout, C.D, Fee, J.A. | 登録日 | 2007-07-23 | 公開日 | 2007-12-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | An unexpected outcome of surface engineering an integral membrane protein: improved crystallization of cytochrome ba(3) from Thermus thermophilus. Acta Crystallogr.,Sect.F, 63, 2007
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2LHD
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![BU of 2lhd by Molmil](/molmil-images/mine/2lhd) | GB98 solution structure | 分子名称: | GB98 | 著者 | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | 登録日 | 2011-08-08 | 公開日 | 2012-02-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Mutational tipping points for switching protein folds and functions. Structure, 20, 2012
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3HX1
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![BU of 3hx1 by Molmil](/molmil-images/mine/3hx1) | Crystal structure of the Slr1951 protein from Synechocystis sp. Northeast Structural Genomics Consortium Target SgR167A | 分子名称: | Slr1951 protein | 著者 | Vorobiev, S, Chen, Y, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-19 | 公開日 | 2009-06-30 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the Slr1951 protein from Synechocystis sp. To be Published
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2LU1
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![BU of 2lu1 by Molmil](/molmil-images/mine/2lu1) | pfsub2 solution NMR structure | 分子名称: | Subtilase | 著者 | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | 登録日 | 2012-06-06 | 公開日 | 2012-10-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum. Proteins, 80, 2012
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3LOI
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![BU of 3loi by Molmil](/molmil-images/mine/3loi) | Crystal structures of Cupin superfamily BbDUF985 from Branchiostoma belcheri tsingtauense in the apo and GDP-bound forms | 分子名称: | Putative uncharacterized protein | 著者 | Zou, C.Z, Du, Y, He, Y.-X, Saren, G, Zhang, X, Chen, Y, Zhang, S.-C. | 登録日 | 2010-02-04 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of the apo and GDP-bound forms of a cupin-like protein BbDUF985 from Branchiostoma belcheri tsingtauense Proteins, 2010
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3HXJ
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![BU of 3hxj by Molmil](/molmil-images/mine/3hxj) | Crystal Structure of Pyrrolo-quinoline quinone (PQQ_DH) from Methanococcus maripaludis, Northeast Structural Genomics Consortium Target MrR86 | 分子名称: | Pyrrolo-quinoline quinone, SULFATE ION | 著者 | Forouhar, F, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-20 | 公開日 | 2009-08-25 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target MrR86 To be Published
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2MH8
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![BU of 2mh8 by Molmil](/molmil-images/mine/2mh8) | GA-79-MBP cs-rosetta structures | 分子名称: | GA-79-MBP, maltose binding protein | 著者 | He, Y, Chen, Y, Porter, L, Bryan, P, Orban, J. | 登録日 | 2013-11-19 | 公開日 | 2015-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Subdomain interactions foster the design of two protein pairs with 80% sequence identity but different folds. Biophys.J., 108, 2015
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3I3U
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![BU of 3i3u by Molmil](/molmil-images/mine/3i3u) | Crystal structure of lp_1913 protein from lactobacillus plantarum, northeast structural genomics Consortium target lpr140a | 分子名称: | uncharacterized protein lp_1913 | 著者 | Seetharaman, J, Chen, Y, Forouhar, F, Sahdev, S, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-30 | 公開日 | 2009-07-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of lp_1913 protein from lactobacillus plantarum, northeast structural genomics Consortium target lpr140a To be Published
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3NZ3
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![BU of 3nz3 by Molmil](/molmil-images/mine/3nz3) | Crystal structure of the mucin-binding domain of Spr1345 from Streptococcus pneumoniae | 分子名称: | Putative uncharacterized protein, SULFATE ION, TRIETHYLENE GLYCOL | 著者 | Du, Y, He, Y.-X, Zhang, Z.-Y, Yang, Y.-H, Shi, W.-W, Frolet, C, Guilmi, A.M, Vernet, T, Zhou, C.-Z, Chen, Y. | 登録日 | 2010-07-15 | 公開日 | 2011-04-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the mucin-binding domain of Spr1345 from Streptococcus pneumoniae J.Struct.Biol., 174, 2011
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3IPF
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![BU of 3ipf by Molmil](/molmil-images/mine/3ipf) | Crystal structure of the Q251Q8_DESHY protein from Desulfitobacterium hafniense. Northeast Structural Genomics Consortium Target DhR8c. | 分子名称: | uncharacterized protein | 著者 | Vorobiev, S.M, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Andre, I, Rossi, P, Kennedy, M, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-08-17 | 公開日 | 2009-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.988 Å) | 主引用文献 | Crystal structure of the Q251Q8_DESHY protein from Desulfitobacterium hafniense. To be Published
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3LZZ
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![BU of 3lzz by Molmil](/molmil-images/mine/3lzz) | Crystal structures of Cupin superfamily BbDUF985 from Branchiostoma belcheri tsingtauense in apo and GDP-bound forms | 分子名称: | ACETATE ION, GUANOSINE-5'-DIPHOSPHATE, Putative uncharacterized protein | 著者 | Du, Y, He, Y.-X, Saren, G, Zhang, X, Zhang, S.-C, Chen, Y, Zhou, C.-Z. | 登録日 | 2010-03-02 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the apo and GDP-bound forms of a cupin-like protein BbDUF985 from Branchiostoma belcheri tsingtauense Proteins, 2010
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3ILM
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![BU of 3ilm by Molmil](/molmil-images/mine/3ilm) | Crystal Structure of the Alr3790 protein from Anabaena sp. Northeast Structural Genomics Consortium Target NsR437h | 分子名称: | Alr3790 protein, MANGANESE (II) ION | 著者 | Vorobiev, S, Chen, Y, Maglaqui, M, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-08-07 | 公開日 | 2009-09-22 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.262 Å) | 主引用文献 | Crystal Structure of the Alr3790 protein from Anabaena sp. To be Published
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