Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8IG5
DownloadVisualize
BU of 8ig5 by Molmil
Crystal structure of SARS main protease in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Lin, C, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG6
DownloadVisualize
BU of 8ig6 by Molmil
Crystal structure of MERS main protease in complex with GC376
分子名称: N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide, ORF1a
著者Lin, C, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG8
DownloadVisualize
BU of 8ig8 by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG7
DownloadVisualize
BU of 8ig7 by Molmil
Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, P, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IG9
DownloadVisualize
BU of 8ig9 by Molmil
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zou, X.F, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8IGA
DownloadVisualize
BU of 8iga by Molmil
Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Wang, J, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
2PZ5
DownloadVisualize
BU of 2pz5 by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-17
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2QJ0
DownloadVisualize
BU of 2qj0 by Molmil
Structure of the yeast U-box-containing ubiquitin ligase Ufd2p
分子名称: Ubiquitin conjugation factor E4
著者Tu, D, Brunger, A.T.
登録日2007-07-06
公開日2007-09-18
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Inaugural Article: Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PVF
DownloadVisualize
BU of 2pvf by Molmil
Crystal Structure of Tyrosine Phosphorylated Activated FGF Receptor 2 (FGFR2) Kinase Domain in Complex with ATP Analog and Substrate Peptide
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H, Mohammadi, M.
登録日2007-05-09
公開日2007-09-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
7YQE
DownloadVisualize
BU of 7yqe by Molmil
Structure of human SRC regulatory domains in complex with the C-terminal PRRP motifs of GPR54.
分子名称: Proto-oncogene tyrosine-protein kinase Src,KiSS-1 receptor
著者Song, G, Xu, S.
登録日2022-08-06
公開日2023-08-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src.
Nat Commun, 15, 2024
6A40
DownloadVisualize
BU of 6a40 by Molmil
complex structure of Alginate lyase AlyF-OU02 with G4
分子名称: alginate lyase AlyF-OU02, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid
著者Liu, W.Z, Lyu, Q.Q, Zhang, K.K.
登録日2018-06-18
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution.
Biochim Biophys Acta Gen Subj, 1863, 2019
2PSQ
DownloadVisualize
BU of 2psq by Molmil
Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain
分子名称: Fibroblast growth factor receptor 2, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-07
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PVY
DownloadVisualize
BU of 2pvy by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-10
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZR
DownloadVisualize
BU of 2pzr by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
6OQ3
DownloadVisualize
BU of 6oq3 by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi2
分子名称: 2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Gingras, A.R.
登録日2019-04-25
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
Faseb Bioadv, 2021
7YJK
DownloadVisualize
BU of 7yjk by Molmil
Cryo-EM structure of the dimeric atSPT-ORM1 complex
分子名称: Long chain base biosynthesis protein 1, Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ...
著者Xie, T, Liu, P, Gong, X.
登録日2022-07-20
公開日2023-04-05
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
7BV8
DownloadVisualize
BU of 7bv8 by Molmil
Mature 50S ribosomal subunit from RrmJ knock out E.coli strain
分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
著者Wang, W, Li, W.Q, Ge, X.L, Yan, K.G, Mandava, C.S, Sanyal, S, Gao, N.
登録日2020-04-09
公開日2020-07-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OQ4
DownloadVisualize
BU of 6oq4 by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi1
分子名称: 2-{(Z)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-[(1S)-1-phenylethyl]benzamide, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Gingras, A.R.
登録日2019-04-25
公開日2020-06-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.754 Å)
主引用文献Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
Faseb Bioadv, 2021
6P4Y
DownloadVisualize
BU of 6p4y by Molmil
Crystal Structure of anti-IL-7Ralpha 4A10 Fab
分子名称: 4A10 Fab heavy chain, 4A10 Fab light chain
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-05-29
公開日2019-09-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P67
DownloadVisualize
BU of 6p67 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-06-03
公開日2019-09-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
6P50
DownloadVisualize
BU of 6p50 by Molmil
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-7 receptor subunit alpha, anti-IL-7R 4A10 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-05-29
公開日2019-09-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
2Q0B
DownloadVisualize
BU of 2q0b by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-21
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
7YJO
DownloadVisualize
BU of 7yjo by Molmil
Cryo-EM structure of the monomeric atSPT-ORM1 (LCB2a-deltaN5) complex
分子名称: Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORMDL family protein, ...
著者Xie, T, Liu, P, Gong, X.
登録日2022-07-20
公開日2023-04-05
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
7YJM
DownloadVisualize
BU of 7yjm by Molmil
Cryo-EM structure of the monomeric atSPT-ORM1 complex
分子名称: Long chain base biosynthesis protein 2a, N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide, ORMDL family protein, ...
著者Xie, T, Liu, P, Gong, X.
登録日2022-07-20
公開日2023-04-05
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023
7YJN
DownloadVisualize
BU of 7yjn by Molmil
Cryo-EM structure of the monomeric atSPT-ORM1 (ORM1-N17A) complex
分子名称: Long chain base biosynthesis protein 1, Long chain base biosynthesis protein 2a, ORMDL family protein, ...
著者Xie, T, Liu, P, Gong, X.
登録日2022-07-20
公開日2023-04-05
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex.
Sci Adv, 9, 2023

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon