4KIK
 
 | | Human IkB kinase beta | | 分子名称: | Inhibitor of nuclear factor kappa-B kinase subunit beta, K-252A | | 著者 | Liu, S, Mosyak, L. | | 登録日 | 2013-05-02 | | 公開日 | 2013-06-26 | | 最終更新日 | 2013-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Crystal Structure of a Human I kappa B Kinase beta Asymmetric Dimer.
J.Biol.Chem., 288, 2013
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4MRM
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist phaclofen | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-17 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MR9
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist SCH50911 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-17 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MS4
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the agonist baclofen | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-18 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MQE
 | | Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-16 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MR8
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP35348 | | 分子名称: | (S)-(3-aminopropyl)(diethoxymethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-17 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MS3
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the endogenous agonist GABA | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-18 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MR7
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP54626 | | 分子名称: | (R)-(cyclohexylmethyl)[(2S)-3-{[(1S)-1-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropyl]phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-17 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MS1
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP46381 | | 分子名称: | (S)-(3-aminopropyl)(cyclohexylmethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-18 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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4MQF
 | | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist 2-hydroxysaclofen | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-hydroxysaclofen, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | | 登録日 | 2013-09-16 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structural mechanism of ligand activation in human GABA(B) receptor.
Nature, 504, 2013
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1JJC
 | | Crystal structure at 2.6A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese | | 分子名称: | ADENOSINE-5'-[PHENYLALANINYL-PHOSPHATE], MANGANESE (II) ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ... | | 著者 | Safro, M.G, Fishman, R, Moor, N, Ankilova, V. | | 登録日 | 2001-07-04 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure at 2.6 A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese.
Acta Crystallogr.,Sect.D, 57, 2001
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1B70
 | | PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE | | 分子名称: | MAGNESIUM ION, PHENYLALANINE, PHENYLALANYL-TRNA SYNTHETASE | | 著者 | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | | 登録日 | 1999-01-26 | | 公開日 | 2000-02-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue
J.Mol.Biol., 287, 1999
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1B7Y
 | | PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINYL-ADENYLATE | | 分子名称: | ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PROTEIN (PHENYLALANYL-TRNA SYNTHETASE) | | 著者 | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | | 登録日 | 1999-01-26 | | 公開日 | 2000-01-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue.
J.Mol.Biol., 287, 1999
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1XJD
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3FXY
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3FY1
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2PJT
 | | Crystal structure of the catalytic domain of MMP-13 complexed with WAY-344 | | 分子名称: | CALCIUM ION, Collagenase 3, TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE, ... | | 著者 | Xu, Z, Huang, A, Lovering, F, Levin, J.I, Mosyak, L. | | 登録日 | 2007-04-16 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-based design of TACE selective inhibitors: manipulations in the S1'-S3' pocket.
Bioorg.Med.Chem., 15, 2007
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4HGM
 | | Shark IgNAR Variable Domain | | 分子名称: | 1,2-ETHANEDIOL, ACETYL GROUP, Serum albumin, ... | | 著者 | Olland, A, Kovalenko, O.V, King, D, Svenson, K. | | 登録日 | 2012-10-08 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
J.Biol.Chem., 288, 2013
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4HGK
 | | Shark IgNAR variable domain | | 分子名称: | Serum albumin, shark V-NAR antibody | | 著者 | Olland, A.O, Kovalenko, O.V, Svenson, K, King, D. | | 登録日 | 2012-10-08 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.
J.Biol.Chem., 288, 2013
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3H0E
 | | 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as Potent Non-Peptidic Inhibitors of Caspase-3 | | 分子名称: | (10S)-3,3-dimethyl-8-{[(2S)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl}-2,3,4,10-tetrahydropyrimido[1,2-a]indol-10-ol, Caspase-3 | | 著者 | Xu, W. | | 登録日 | 2009-04-09 | | 公開日 | 2009-11-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3
Bioorg.Med.Chem., 17, 2009
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5F3H
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5F3B
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1NLR
 | | ENDO-1,4-BETA-GLUCANASE CELB2, CELLULASE, NATIVE STRUCTURE | | 分子名称: | ENDO-1,4-BETA-GLUCANASE | | 著者 | Sulzenbacher, G, Dupont, C, Davies, G.J. | | 登録日 | 1997-10-27 | | 公開日 | 1998-11-25 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The Streptomyces lividans family 12 endoglucanase: construction of the catalytic cre, expression, and X-ray structure at 1.75 A resolution.
Biochemistry, 36, 1997
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