3FXY

Acidic Mammalian Chinase, Catalytic Domain

Summary for 3FXY

• Entry DOI: 10.2210/pdb3fxy/pdb
• Related: 3FY1
• Descriptor: Acidic mammalian chitinase (2 entities in total)
• Functional Keywords: chitinase, asthma, chitin degradation, alternative splicing, carbohydrate metabolism, chitin-binding, cytoplasm, glycosidase, hydrolase, polymorphism, polysaccharide degradation, secreted
• Biological source: Homo sapiens (human)
• Cellular location: Secreted. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: Q9BZP6
• Total number of polymer chains: 4
• Total formula weight: 176813.48

Authors

Olland, A.M. (deposition date: 2009-01-21, release date: 2009-03-10, Last modification date: 2011-07-13)

• Primary citation: Olland, A.M.,Strand, J.,Presman, E.,Czerwinski, R.,Joseph-McCarthy, D.,Krykbaev, R.,Schlingmann, G.,Chopra, R.,Lin, L.,Fleming, M.,Kriz, R.,Stahl, M.,Somers, W.,Fitz, L.,Mosyak, L.; Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.; Protein Sci., 18:569-578, 2009; PubMed: 19241384; DOI: 10.1002/pro.63

Experimental method

X-RAY DIFFRACTION (2 Å)