4HGM

Shark IgNAR Variable Domain

Summary for 4HGM

• Entry DOI: 10.2210/pdb4hgm/pdb
• Related: 4HGK
• Descriptor: Shark V-NAR, Serum albumin, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: ig-fold, human albumin, v-nar, immune system
• Biological source: Squalus acanthias (Dogfish Shark); More
• Cellular location: Secreted: P02768
• Total number of polymer chains: 2
• Total formula weight: 79038.93

Authors

Olland, A.,Kovalenko, O.V.,King, D.,Svenson, K. (deposition date: 2012-10-08, release date: 2013-05-08, Last modification date: 2024-03-06)

• Primary citation: Kovalenko, O.V.,Olland, A.,Piche-Nicholas, N.,Godbole, A.,King, D.,Svenson, K.,Calabro, V.,Muller, M.R.,Barelle, C.J.,Somers, W.,Gill, D.S.,Mosyak, L.,Tchistiakova, L.; Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis.; J.Biol.Chem., 288:17408-17419, 2013; PubMed: 23632026; DOI: 10.1074/jbc.M112.435289

Experimental method

X-RAY DIFFRACTION (2.34 Å)