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Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide
分子名称:	CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
著者	McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D.
登録日	2012-10-24
公開日	2013-02-06
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.694 Å)
主引用文献	Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013

7LD1

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-12
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LCN

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1050.1 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-11
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.35 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

6P3B

Crystal structure of the anti-HIV antibody DH501 unmutated common ancestor (UCA)
分子名称:	1,2-ETHANEDIOL, DH501UCA Fab Heavy chain, DH501UCA Fab Light chain
著者	Nicely, N.I, Saunders, K.O.
登録日	2019-05-23
公開日	2019-11-20
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.02 Å)
主引用文献	Cooperation between somatic mutation and germline-encoded residues enable antibody recognition of HIV-1 envelope glycans. Plos Pathog., 15, 2019

6P8N

Crystal Structure of Antibody P-p1f1 in Complex with eOD-GT8
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者	Weidle, C, Pancera, M.
登録日	2019-06-07
公開日	2019-11-20
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.202 Å)
主引用文献	Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Rep, 29, 2019

6P6F

BG505 SOSIP-I53-50NP
分子名称:	I53-50A.1NT1, I53-50B.4PT1
著者	Berndsen, Z.T, Ward, A.B.
登録日	2019-06-03
公開日	2019-06-19
最終更新日	2019-12-18
実験手法	ELECTRON MICROSCOPY (4.5 Å)
主引用文献	Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle. Nat Commun, 10, 2019

6P8M

Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者	Weidle, C, Pancera, M.
登録日	2019-06-07
公開日	2019-11-20
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.594 Å)
主引用文献	Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Rep, 29, 2019

6ORO

Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ...
著者	Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日	2019-04-30
公開日	2019-06-12
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019

6ORQ

Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ...
著者	Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日	2019-04-30
公開日	2019-06-12
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (4.4 Å)
主引用文献	Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019

6ORN

Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074
分子名称:	10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日	2019-04-30
公開日	2019-06-12
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (4.05 Å)
主引用文献	Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019

6ORP

Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ...
著者	Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日	2019-04-30
公開日	2019-06-12
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (4.4 Å)
主引用文献	Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019

5DD5

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称:	ANTI-HIV ANTIBODY DH570.9 FAB HEAVY CHAIN
著者	Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日	2015-08-24
公開日	2016-05-11
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

5DD6

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称:	ANTI-HIV ANTIBODY DH570.mut58 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.mut58 FAB LIGHT CHAIN
著者	Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日	2015-08-24
公開日	2016-05-11
最終更新日	2019-12-11
実験手法	X-RAY DIFFRACTION (1.699 Å)
主引用文献	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

5DD3

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称:	ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
著者	Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日	2015-08-24
公開日	2016-05-11
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.797 Å)
主引用文献	Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016

5F6I

Crystal Structure of Tier 2 Neutralizing Antibody DH428 from a Rhesus Macaque
分子名称:	DH428 Antibody Heavy Chain, DH428 Antibody Light Chain
著者	Fera, D, Harrison, S.C.
登録日	2015-12-06
公開日	2016-01-13
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.32 Å)
主引用文献	Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016

5F6H

Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque
分子名称:	DH427 Antibody Heavy Chain, DH427 Antibody Light Chain
著者	Fera, D, Harrison, S.C.
登録日	2015-12-06
公開日	2016-01-13
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.66 Å)
主引用文献	Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016

5F6J

Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core
分子名称:	DH427 Antibody Heavy Chain, DH427 Antibody Light Chain, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C
著者	Fera, D, Harrison, S.C.
登録日	2015-12-06
公開日	2016-01-13
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (6.63 Å)
主引用文献	Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Rep, 14, 2016

6VFK

De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
分子名称:	BG505-SOSIP-T33_dn10A, T33_dn10B
著者	Antanasijevic, A, Ward, A.B.
登録日	2020-01-05
公開日	2020-07-22
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (4.25 Å)
主引用文献	Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. Plos Pathog., 16, 2020

6VFL

BG505-SOSIP model reconstructed by subparticle extraction and refinement from a tetrahedral nanoparticle T33_dn10
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIPv5.2(7S) - gp120, ...
著者	Antanasijevic, A, Ward, A.B.
登録日	2020-01-05
公開日	2020-07-22
最終更新日	2020-08-26
実験手法	ELECTRON MICROSCOPY (4.14 Å)
主引用文献	Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. Plos Pathog., 16, 2020

6VBP

Crystal structure of anti-HIV-1 antibody DH815 bound to gp120 V2 peptide
分子名称:	CHLORIDE ION, DH815 heavy chain, DH815 light chain, ...
著者	Janus, B.M, Ofek, G.
登録日	2019-12-19
公開日	2020-02-12
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.298 Å)
主引用文献	HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. JCI Insight, 5, 2020

6VBQ

Crystal structure of anti-HIV-1 antibody DH822 bound to gp120 V2 peptide
分子名称:	DH822 heavy chain, DH822 light chain, Envelope glycoprotein gp160
著者	Janus, B.M, Ofek, G.
登録日	2019-12-19
公開日	2020-02-12
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.116 Å)
主引用文献	HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. JCI Insight, 5, 2020

6VBO

Crystal structure of anti-HIV-1 antibody DH813 bound to gp120 V2 peptide
分子名称:	DH813 heavy chain, DH813 light chain, Envelope glycoprotein gp160
著者	Janus, B.M, Ofek, G.
登録日	2019-12-19
公開日	2020-02-12
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.683 Å)
主引用文献	HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. JCI Insight, 5, 2020

6VTU

DH717.1 Fab monomer in complex with man9 glycan
分子名称:	DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ...
著者	Fera, D, Bronkema, N.
登録日	2020-02-13
公開日	2020-12-30
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.61 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

6VO3

AMC009 SOSIP.v4.2 in complex with PGV04 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ...
著者	Cottrell, C.A, de Val, N, Ward, A.B.
登録日	2020-01-29
公開日	2020-09-23
最終更新日	2020-12-09
実験手法	ELECTRON MICROSCOPY (4.25 Å)
主引用文献	Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers. J.Virol., 94, 2020

6U6O

Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846
分子名称:	DH846 Fab heavy chain, DH846 Fab light chain
著者	Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G.
登録日	2019-08-30
公開日	2021-03-24
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.806 Å)
主引用文献	Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathog., 17, 2021

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