6VFK

De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface

Summary for 6VFK

Entry DOI	10.2210/pdb6vfk/pdb
EMDB information	21185 21186
Descriptor	T33_dn10B, BG505-SOSIP-T33_dn10A (2 entities in total)
Functional Keywords	nanoparticle, rosetta, de novo protein design, hiv env, de novo protein
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	120322.12
Authors	Antanasijevic, A.,Ward, A.B. (deposition date: 2020-01-05, release date: 2020-07-22, Last modification date: 2024-03-06)
Primary citation	Antanasijevic, A.,Ueda, G.,Brouwer, P.J.M.,Copps, J.,Huang, D.,Allen, J.D.,Cottrell, C.A.,Yasmeen, A.,Sewall, L.M.,Bontjer, I.,Ketas, T.J.,Turner, H.L.,Berndsen, Z.T.,Montefiori, D.C.,Klasse, P.J.,Crispin, M.,Nemazee, D.,Moore, J.P.,Sanders, R.W.,King, N.P.,Baker, D.,Ward, A.B. Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. Plos Pathog., 16:e1008665-e1008665, 2020 Cited by PubMed: 32780770 DOI: 10.1371/journal.ppat.1008665 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.25 Å)

Structure validation