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2G8G
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BU of 2g8g by Molmil
Structurally mapping the diverse phenotype of Adeno-Associated Virus serotype 4
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid
著者Govindasamy, L, Padron, E, McKenna, R, Muzyczka, N, Chiorini, J.A, Agbandje-McKenna, M.
登録日2006-03-02
公開日2007-01-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.
J.Virol., 80, 2006
5WLV
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BU of 5wlv by Molmil
Carbonic Anhydrase II in complex with aryloxy-2-hydroxypropylammine sulfonamide
分子名称: 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Lomelino, C.L, Andring, J.T, McKenna, R.
登録日2017-07-27
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
J. Med. Chem., 61, 2018
5WLR
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BU of 5wlr by Molmil
Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
分子名称: 4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}benzene-1-sulfonamide, Carbonic Anhydrase IX-mimic, GLYCEROL, ...
著者Lomelino, C.L, Andring, J.T, McKenna, R.
登録日2017-07-27
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Hybrids for multitargeted therapy Beta Adrenergic Receptor modulators CAIs
To Be Published
3EKI
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BU of 3eki by Molmil
Structural insights of the Mycoplasma hyorhinis protein Mh-p37: A putative thiamine pyrophosphate transporter
分子名称: BROMIDE ION, CALCIUM ION, GLYCEROL, ...
著者Sippel, K.H, Robbins, A.H, Reutzel, R, McKenna, R.
登録日2008-09-19
公開日2009-06-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis
J.Bacteriol., 191, 2009
5WLT
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BU of 5wlt by Molmil
Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
分子名称: 4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
著者Lomelino, C.L, Andring, J.T, McKenna, R.
登録日2017-07-27
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
J. Med. Chem., 61, 2018
4RSO
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BU of 4rso by Molmil
The structure of the neurotropic AAVrh.8 viral vector
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, CHLORIDE ION, Capsid protein VP1, ...
著者Halder, S, Van Vliet, K, Smith, J.K, McKenna, R, Wilson, J.M, Agbandje-McKenna, M.
登録日2014-11-10
公開日2016-04-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of neurotropic adeno-associated virus AAVrh.8.
J.Struct.Biol., 192, 2015
3HS4
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BU of 3hs4 by Molmil
Human carbonic anhydrase II complexed with acetazolamide
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, GLYCEROL, ...
著者Robbins, A.H, Genis, C, Domsic, J, Sippel, K.H, Agbandje-McKenna, M, McKenna, R.
登録日2009-06-10
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design.
Acta Crystallogr.,Sect.F, 65, 2009
2OSF
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BU of 2osf by Molmil
Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study
分子名称: 4-MERCAPTOBENZENE-1,3-DIOL, Carbonic anhydrase 2, S-(2,4-dihydroxyphenyl) hydrogen thiocarbonate, ...
著者Albert, A.B, Caroli, G, Govindasamy, L, Agbandje-McKenna, M, McKenna, R, Tripp, B.C.
登録日2007-02-05
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural study.
Biochemistry, 47, 2008
2OSM
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BU of 2osm by Molmil
Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study
分子名称: 2-MERCAPTOPHENOL, Carbonic anhydrase 2, ZINC ION
著者Albert, A.B, Caroli, G, Govindasamy, L, Agbandje-Mckenna, M, McKenna, R, Tripp, B.C.
登録日2007-02-06
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study.
Biochemistry, 47, 2008
1RDW
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BU of 1rdw by Molmil
Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Reutzel, R, Yoshioka, C, Govindasamy, L, Yarmola, E.G, Agbandje-Mckenna, M, Bubb, M.R, Mckenna, R.
登録日2003-11-06
公開日2003-12-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
1RFQ
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BU of 1rfq by Molmil
Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Reutzel, R, Yoshioka, C, Govindasamy, L, Yarmola, E.G, Agbandje-McKenna, M, Bubb, M.R, McKenna, R.
登録日2003-11-10
公開日2003-12-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
4QC8
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BU of 4qc8 by Molmil
Structural annotation of pathogenic bovine Parvovirus-1
分子名称: VP2
著者Kailasan, S, Halder, S, Gurda, B.L, Bladek, H, Chipman, P.R, McKenna, R, Brown, K, Agbandje-McKenna, M.
登録日2014-05-09
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of an enteric pathogen, bovine parvovirus.
J.Virol., 89, 2015
7S1W
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BU of 7s1w by Molmil
The AAVrh.10-glycan complex
分子名称: Capsid protein VP1, beta-D-galactopyranose
著者Mietzsch, M, McKenna, R.
登録日2021-09-02
公開日2021-09-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural Study of Aavrh.10 Receptor and Antibody Interactions.
J.Virol., 95, 2021
1G0F
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BU of 1g0f by Molmil
SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Duda, D, McKenna, R.
登録日2000-10-06
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry, 40, 2001
1G0E
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BU of 1g0e by Molmil
SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 4-METHYLIMIDAZOLE
分子名称: 4-METHYLIMIDAZOLE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
著者Duda, D, McKenna, R.
登録日2000-10-06
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Biochemistry, 40, 2001
6WH7
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BU of 6wh7 by Molmil
Capsid structure of Penaeus monodon metallodensovirus following EDTA treatment
分子名称: Penaeus monodon metallodensovirus major capsid protein
著者Penzes, J.J, Pham, H.T, Chipman, P, Bhattacharya, N, McKenna, R, Agbandje-McKenna, M, Tijssen, P.
登録日2020-04-07
公開日2020-04-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution.
Proc.Natl.Acad.Sci.USA, 117, 2020
4G0R
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BU of 4g0r by Molmil
Structural characterization of H-1 Parvovirus: comparison of infectious virions to replication defective particles
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, ...
著者Halder, S, Agbandje-McKenna, M, Nam, H.-J, Govindasamy, L, Vogel, M, Dinsart, C, Salome, N, McKenna, R.
登録日2012-07-09
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural characterization of h-1 parvovirus: comparison of infectious virions to empty capsids.
J.Virol., 87, 2013
3UX1
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BU of 3ux1 by Molmil
Structural Characterization of Adeno-Associated Virus Serotype 9
分子名称: Capsid protein VP1
著者DiMattia, M.A, Nam, H.-J, Van Vliet, K, Mitchell, M, McCall, A, Bennett, A, Gurda, B, McKenna, R, Potter, M, Sakai, Y, Byrne, B.J, Muzyczka, N, Aslanidi, G, Zolotukhin, S, Olson, N, Sinkovitis, R, Baker, T.S, Agbandje-McKenna, M.
登録日2011-12-03
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insight into the unique properties of adeno-associated virus serotype 9.
J.Virol., 86, 2012
4GBT
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BU of 4gbt by Molmil
Structural characterization of H-1 Parvovirus: comparison of infectious virions to replication defective particles
分子名称: CHLORIDE ION, Capsid protein VP1, SODIUM ION
著者Halder, S, Nam, H.-J, Govindasamy, L, Vogel, M, Dinsart, C, Salome, N, McKenna, R, Agbandje-McKenna, M.
登録日2012-07-27
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural characterization of h-1 parvovirus: comparison of infectious virions to empty capsids.
J.Virol., 87, 2013
1S5O
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BU of 1s5o by Molmil
Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase
分子名称: CARNITINE, carnitine acetyltransferase isoform 2
著者Govindasamy, L, Kukar, T, Lian, W, Pedersen, B, Gu, Y, Agbandje-Mckenna, M, Jin, S, Mckenna, R, Wu, D.
登録日2004-01-21
公開日2004-02-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.
J.Struct.Biol., 146, 2004
3IXO
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BU of 3ixo by Molmil
Crystal Structure of uncomplexed HIV_1 Protease Subtype A
分子名称: HIV-1 protease
著者Robbins, A, McKenna, R.
登録日2009-09-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypes.
Acta Crystallogr.,Sect.D, 66, 2010
3GZ0
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BU of 3gz0 by Molmil
Apo-human carbonic anhydrase II revisited: Implications of the loss of a metal in protein structure, stability and solvent network
分子名称: Carbonic anhydrase 2, ZINC ION
著者Avvaru, B.S, McKenna, R.
登録日2009-04-06
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Apo-Human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability, and Solvent Network .
Biochemistry, 48, 2009
4IOV
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BU of 4iov by Molmil
The structure of AAVrh32.33, a Novel Gene Delivery Vector
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein VP1
著者Mikalism, K, Nam, H.-J, Van vilet, K, Vandenberghe, L.H, Mays, L.E, McKenna, R, Wilson, J, Agbandje-McKenna, M.
登録日2013-01-08
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The structure of AAVrh32.33, a novel gene delivery vector.
J.Struct.Biol., 186, 2014
5DVX
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BU of 5dvx by Molmil
Crystal structure of the catalytic-domain of human carbonic anhydrase IX at 1.6 angstrom resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Carbonic anhydrase 9, ...
著者Mahon, B.P, Socorro, L, Driscoll, J.M, McKenna, R.
登録日2015-09-21
公開日2016-08-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis.
Biochemistry, 55, 2016
2NXS
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BU of 2nxs by Molmil
Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase II
分子名称: SULFATE ION, ZINC ION, carbonic anhydrase 2
著者Fisher, S.Z, McKenna, R.
登録日2006-11-19
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007

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