1G0E
SITE-SPECIFIC MUTANT (HIS64 REPLACED WITH ALA) OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH 4-METHYLIMIDAZOLE
Summary for 1G0E
Entry DOI | 10.2210/pdb1g0e/pdb |
Related | 1G0F |
Descriptor | CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | twisted beta sheet, chemical rescue, 4-methylimidazole, zinc metalloenzyme, protein ligand complex, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29570.09 |
Authors | Duda, D.,McKenna, R. (deposition date: 2000-10-06, release date: 2000-10-18, Last modification date: 2024-02-07) |
Primary citation | Duda, D.,Tu, C.,Qian, M.,Laipis, P.,Agbandje-McKenna, M.,Silverman, D.N.,McKenna, R. Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II. Biochemistry, 40:1741-1748, 2001 Cited by PubMed: 11327835DOI: 10.1021/bi002295z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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