1ZOQ
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![BU of 1zoq by Molmil](/molmil-images/mine/1zoq) | IRF3-CBP complex | 分子名称: | CREB-binding protein, Interferon regulatory factor 3 | 著者 | Qin, B, Lin, K. | 登録日 | 2005-05-13 | 公開日 | 2006-03-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Crystal structure of IRF-3 in complex with CBP. Structure, 13, 2005
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3NMW
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![BU of 3nmw by Molmil](/molmil-images/mine/3nmw) | Crystal structure of armadillo repeats domain of APC | 分子名称: | APC variant protein, SULFATE ION | 著者 | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | 登録日 | 2010-06-22 | 公開日 | 2011-07-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
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3NMX
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![BU of 3nmx by Molmil](/molmil-images/mine/3nmx) | Crystal structure of APC complexed with Asef | 分子名称: | APC variant protein, Rho guanine nucleotide exchange factor 4 | 著者 | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | 登録日 | 2010-06-22 | 公開日 | 2011-07-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
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8SH4
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![BU of 8sh4 by Molmil](/molmil-images/mine/8sh4) | Crystal structure of the tRNA (m1G37) methyltransferase apoenzyme from Anaplasma phagocytophilum | 分子名称: | GLYCEROL, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Jannotta, C, Edele, D, Levanti, D, Carson, M, Prucha, G, Caesar, J, Picchiello, C, Collins, K, Garland, E, Handley-Pendleton, J, Hernandez, V, Leffler, S, Williams, D, Stojanoff, V, Perez, A, Halloran, J, Bolen, R. | 登録日 | 2023-04-13 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the m1G37 tRNA methyltransferase apoenzyme from Anaplasma phagocytophilum To Be Published
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3VAX
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![BU of 3vax by Molmil](/molmil-images/mine/3vax) | Crystal structure of DndA from streptomyces lividans | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein dndA | 著者 | Zhang, Z, Chen, F, Lin, K, Wu, G. | 登録日 | 2011-12-30 | 公開日 | 2013-01-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation Plos One, 7, 2012
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3DSH
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![BU of 3dsh by Molmil](/molmil-images/mine/3dsh) | Crystal structure of dimeric interferon regulatory factor 5 (IRF-5) transactivation domain | 分子名称: | Interferon regulatory factor 5 | 著者 | Chen, W, Lam, S.S, Srinath, H, Jiang, Z, Correia, J.J, Schiffer, C, Fitzgerald, K.A, Lin, K, Royer Jr, W.E. | 登録日 | 2008-07-12 | 公開日 | 2008-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5. Nat.Struct.Mol.Biol., 15, 2008
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1KHU
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![BU of 1khu by Molmil](/molmil-images/mine/1khu) | |
1MJS
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![BU of 1mjs by Molmil](/molmil-images/mine/1mjs) | |
1MK2
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![BU of 1mk2 by Molmil](/molmil-images/mine/1mk2) | SMAD3 SBD complex | 分子名称: | ACETIC ACID, Madh-interacting protein, SMAD 3 | 著者 | Qin, B.Y, Lam, S.S, Correia, J.J, Lin, K. | 登録日 | 2002-08-28 | 公開日 | 2002-10-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control Genes Dev., 16, 2002
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7ED5
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![BU of 7ed5 by Molmil](/molmil-images/mine/7ed5) | A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Shannon, A, Fattorini, V, Sama, B, Selisko, B, Feracci, M, Falcou, C, Gauffre, P, El Kazzi, P, Delpal, A, Decroly, E, Alvarez, K, Eydoux, C, Guillemot, J.-C, Moussa, A, Good, S, Colla, P, Lin, K, Sommadossi, J.-P, Zhu, Y.X, Yan, X.D, Shi, H, Ferron, F, Canard, B. | 登録日 | 2021-03-15 | 公開日 | 2022-02-16 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase. Nat Commun, 13, 2022
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1G88
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![BU of 1g88 by Molmil](/molmil-images/mine/1g88) | S4AFL3ARG515 MUTANT | 分子名称: | SMAD4 | 著者 | Chako, B.M, Qin, B, Lam, S.S, Correia, J.J, Lin, K. | 登録日 | 2000-11-16 | 公開日 | 2000-11-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization. Nat.Struct.Biol., 8, 2001
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1DD1
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![BU of 1dd1 by Molmil](/molmil-images/mine/1dd1) | |
8FX1
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![BU of 8fx1 by Molmil](/molmil-images/mine/8fx1) | Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to (R)-SerMe-ImmH Phosphonate | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, [(3R)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid | 著者 | Hughes, R, Meneely, K.M, Glockzin, K, Clinch, K, Tyler, P.C, Lamb, A.L, Meek, T.D, Katzfuss, A. | 登録日 | 2023-01-23 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. Biochemistry, 62, 2023
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8FX0
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![BU of 8fx0 by Molmil](/molmil-images/mine/8fx0) | Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to (S)-SerMe-ImmH Phosphonate | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, [(3R)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid | 著者 | Hughes, R, Meneely, K.M, Glockzin, K, Clinch, K, Tyler, P.C, Lamb, A.L, Meek, T.D, Katzfuss, A. | 登録日 | 2023-01-23 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. Biochemistry, 62, 2023
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8FWZ
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![BU of 8fwz by Molmil](/molmil-images/mine/8fwz) | Crystal structure of the Trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT), isoform D, bound to Hydroxypropyl-Lin-ImmH Phosphonate | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, PHOSPHATE ION, [(2R)-2-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}propyl]phosphonic acid | 著者 | Hughes, R, Meneely, K.M, Glockzin, K, Clinch, K, Tyler, P.C, Lamb, A.L, Meek, T.D, Katzfuss, A. | 登録日 | 2023-01-23 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. Biochemistry, 62, 2023
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6ZAK
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![BU of 6zak by Molmil](/molmil-images/mine/6zak) | Room temperature XFEL Isopenicillin N synthase structure in complex with the Fe(IV)=O mimic VO and ACV. | 分子名称: | Isopenicillin N synthase, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, SULFATE ION, ... | 著者 | Rabe, P, Kamps, J.J.A.G, Sutherlin, K, Pharm, C, McDonough, M.A, Leissing, T.M, Aller, P, Butryn, A, Linyard, J, Lang, P, Brem, J, Fuller, F.D, Batyuk, A, Hunter, M.S, Pettinati, I, Clifton, I.J, Alonso-Mori, R, Gul, S, Young, I, Kim, I, Bhowmick, A, ORiordan, L, Brewster, A.S, Claridge, T.D.W, Sauter, N.K, Yachandra, V, Yano, J, Kern, J.F, Orville, A.M, Schofield, C.J. | 登録日 | 2020-06-05 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Room temperature XFEL Isopenicillin N synthase structure in complex with the Fe(IV)=O mimic VO and ACV. To Be Published
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5NDA
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![BU of 5nda by Molmil](/molmil-images/mine/5nda) | NMR Structural Characterisation of Pharmaceutically Relevant Proteins Obtained Through a Novel Recombinant Production: The Case of The Pulmonary Surfactant Polypeptide C Analogue rSP-C33Leu. | 分子名称: | rSP-C33Leu -RECOMBINANT PULMONARY SURFACTANT-ASSOCIATED POLYPEPTIDE C ANALOGUE- | 著者 | Venturi, L, Pioselli, B, Johansson, J, Rising, A, Kronqvist, N, Nordling, K. | 登録日 | 2017-03-08 | 公開日 | 2017-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Efficient protein production inspired by how spiders make silk. Nat Commun, 8, 2017
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7BGB
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![BU of 7bgb by Molmil](/molmil-images/mine/7bgb) | The H/ACA RNP lobe of human telomerase | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | 著者 | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | 登録日 | 2021-01-06 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
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7BG9
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![BU of 7bg9 by Molmil](/molmil-images/mine/7bg9) | The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate | 分子名称: | DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ... | 著者 | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | 登録日 | 2021-01-06 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
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2YAD
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![BU of 2yad by Molmil](/molmil-images/mine/2yad) | BRICHOS domain of Surfactant protein C precursor protein | 分子名称: | SURFACTANT PROTEIN C BRICHOS DOMAIN | 著者 | Askarieh, G, Siponen, M.I, Willander, H, Landreh, M, Westermark, P, Nordling, K, Keranen, H, Hermansson, E, Hamvas, A, Nogee, L.M, Bergman, T, Saenz, A, Casals, C, Aqvist, J, Jornvall, H, Presto, J, Johansson, J, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Ekblad, T, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Nordlund, P, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, van den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Berglund, H, Knight, S.D. | 登録日 | 2011-02-18 | 公開日 | 2012-02-15 | 最終更新日 | 2014-08-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High Resolution Structure of a Bricos Domain and its Implications for Anti-Amyloid Chaperone Activity on Lung Surgactant Protein C. Proc.Natl.Acad.Sci.USA, 109, 2012
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2YAK
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![BU of 2yak by Molmil](/molmil-images/mine/2yak) | Structure of death-associated protein Kinase 1 (dapk1) in complex with a ruthenium octasporine ligand (OSV) | 分子名称: | DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4 | 著者 | Feng, L, Geisselbrecht, Y, Blanck, S, Wilbuer, A, Atilla-Gokcumen, G.E, Filippakopoulos, P, Kraeling, K, Celik, M.A, Harms, K, Maksimoska, J, Marmorstein, R, Frenking, G, Knapp, S, Essen, L.-O, Meggers, E. | 登録日 | 2011-02-23 | 公開日 | 2011-04-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors. J.Am.Chem.Soc., 133, 2011
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3LR6
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![BU of 3lr6 by Molmil](/molmil-images/mine/3lr6) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | 分子名称: | Major ampullate spidroin 1, TRIETHYLENE GLYCOL | 著者 | Askarieh, G, Hedhammar, H, Nordling, K, Saenz, A, Casals, C, Rising, A, Johansson, J, Knight, S.D. | 登録日 | 2010-02-10 | 公開日 | 2010-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
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3LR2
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![BU of 3lr2 by Molmil](/molmil-images/mine/3lr2) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1 | 著者 | Askarieh, G, Hedhammar, H, Nordling, K, Johansson, J, Knight, S.D, Rising, A, Casals, C, Saenz, A. | 登録日 | 2010-02-10 | 公開日 | 2010-05-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
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3LR8
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![BU of 3lr8 by Molmil](/molmil-images/mine/3lr8) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Major ampullate spidroin 1, ... | 著者 | Askarieh, G, Hedhammar, H, Nordling, K, Rising, A, Johansson, J, Knight, S.D. | 登録日 | 2010-02-10 | 公開日 | 2010-05-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
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3LRD
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![BU of 3lrd by Molmil](/molmil-images/mine/3lrd) | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay | 分子名称: | 1,2-ETHANEDIOL, Major ampullate spidroin 1, TRIETHYLENE GLYCOL | 著者 | Askarieh, G, Hedhammar, H, Nordling, K, Rising, A, Johansson, J, Knight, S.D, Saenz, A, Casals, C. | 登録日 | 2010-02-11 | 公開日 | 2010-05-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature, 465, 2010
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