7JH3
| Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP | 分子名称: | 4-aminobutyrate aminotransferase PuuE, DI(HYDROXYETHYL)ETHER | 著者 | Valleau, D, Evdokimova, E, Stogios, P.J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-07-20 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Crystal structure of 4-aminobutyrate aminotransferase PuuE from Escherichia coli in complex with PLP To Be Published
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6CD7
| Crystal structure of APH(2")-IVa in complex with plazomicin | 分子名称: | (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro-2H-pyran-2-y l]oxy}-2-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide, APH(2'')-Id, CHLORIDE ION | 著者 | Stogios, P.J, Evdokimova, E, Dong, A, Di Leo, R, Savchenko, A, Satchell, K.J, Joachimiak, J, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-02-08 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4, 2018
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6AOJ
| Crystal structure of Legionella pneumophila effector Ceg4 with N-terminal yeast Hog1p sequence | 分子名称: | CHLORIDE ION, Ceg4, MAGNESIUM ION | 著者 | Stogios, P.J, Nocek, B, Cuff, M.E, Evdokimova, E, Egorova, O, Yim, V, Di Leo, R, Savchenko, A. | 登録日 | 2017-08-16 | 公開日 | 2018-01-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | 主引用文献 | TheLegionella pneumophilaeffector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways. J. Biol. Chem., 293, 2018
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6AOK
| Crystal structure of Legionella pneumophila effector Ceg4 with N-terminal TEV protease cleavage sequence | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Ceg4, ... | 著者 | Stogios, P.J, Cuff, M.E, Nocek, B, Evdokimova, E, Egorova, O, Yim, V, Di Leo, R, Savchenko, A. | 登録日 | 2017-08-16 | 公開日 | 2018-01-10 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | TheLegionella pneumophilaeffector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways. J. Biol. Chem., 293, 2018
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6BNE
| Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, phosphate-bound complex | 分子名称: | ACETATE ION, GLYCEROL, PHOSPHATE ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Di Leo, R, Savchenko, A, Anderson, W.F, Satchell, K.J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-11-16 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis. ACS Chem. Biol., 2018
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6C5C
| Crystal structure of the 3-dehydroquinate synthase (DHQS) domain of Aro1 from Candida albicans SC5314 in complex with NADH | 分子名称: | 1,2-ETHANEDIOL, 3-dehydroquinate synthase, CHLORIDE ION, ... | 著者 | Michalska, K, Evdokimova, E, Di Leo, R, Stogios, P.J, Savchenko, A, Joachimiak, A, Satchell, K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-01-16 | 公開日 | 2018-01-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
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6D2X
| Crystal structure of the GH26 domain from PbGH26-GH5A endo-beta-mannanase/endo-beta-glucanase from Prevotella bryantii | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Aryl-phospho-beta-D-glucosidase BglC, GH1 family, ... | 著者 | Stogios, P.J, Skarina, T, McGregor, N, Di Leo, R, Brumer, H, Savchenko, A. | 登録日 | 2018-04-14 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of the GH26 domain from PbGH26-GH5A endo-beta-mannanase/endo-beta-glucanase from Prevotella bryantii To Be Published
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6BNF
| Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, mono-zinc complex | 分子名称: | ACETATE ION, GLYCEROL, PHOSPHATE ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Di Leo, R, Savchenko, A, Anderson, W.F, Satchell, K.J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-11-16 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis. ACS Chem. Biol., 2018
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6D2Y
| Crystal structure of surface glycan-binding protein PbSGBP-B from Prevotella bryantii | 分子名称: | GLYCEROL, MAGNESIUM ION, PbSGBP-B lipoprotein | 著者 | Stogios, P.J, Skarina, T, Wawrzak, Z, McGregor, N, Di Leo, R, Brumer, H, Savchenko, A. | 登録日 | 2018-04-14 | 公開日 | 2019-10-16 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal structure of surface glycan-binding protein PbSGBP-B from Prevotella bryantii To Be Published
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6D2W
| Crystal structure of Prevotella bryantii endo-beta-mannanase/endo-beta-glucanase PbGH26A-GH5A | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aryl-phospho-beta-D-glucosidase BglC, GH1 family, ... | 著者 | Stogios, P.J, Skarina, T, McGregor, N, Nocek, B, Di Leo, R, Brumer, H, Savchenko, A. | 登録日 | 2018-04-14 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Prevotella bryantii endo-beta-mannanase/endo-beta-glucanase PbGH26A-GH5A To Be Published
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5T06
| Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Hexanoyl-CoA | 分子名称: | 1,2-ETHANEDIOL, Acyl-CoA thioester hydrolase YbgC, HEXANOYL-COENZYME A | 著者 | Watanabe, N, Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-08-15 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Hexanoyl-CoA To be published
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5T07
| Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Decanoyl-CoA | 分子名称: | Acyl-CoA thioester hydrolase YbgC, decanoyl-CoA | 著者 | Watanabe, N, Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-08-15 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.717 Å) | 主引用文献 | Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Decanoyl-CoA To be published
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5UCC
| Crystal structure of the ENTH domain of ENT2 from Candida albicans | 分子名称: | CHLORIDE ION, CITRIC ACID, Potential epsin-like clathrin-binding protein | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-12-22 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structure of the ENTH domain of ENT2 from Candida albicans To Be Published
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5UC7
| Crystal structure of BioA / 7,8-diaminopelargonic acid aminotransferase / DAPA synthase from Citrobacter rodentium, PLP complex | 分子名称: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, D(-)-TARTARIC ACID | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-12-21 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.835 Å) | 主引用文献 | Crystal structure of BioA / 7,8-diaminopelargonic acid aminotransferase / DAPA synthase from Citrobacter rodentium, PLP complex To Be Published
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5U1H
| Crystal structure of the C-terminal peptidoglycan binding domain of OprF (PA1777) from Pseudomonas aeruginosa | 分子名称: | (2R,6S)-2-amino-6-(carboxyamino)-7-{[(1R)-1-carboxyethyl]amino}-7-oxoheptanoic acid, ACETATE ION, CHLORIDE ION, ... | 著者 | Watanabe, N, Stogios, P.J, Skarina, T, Wawrzak, Z, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-11-28 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the C-terminal peptidoglycan binding domain of OprF (PA1777) from Pseudomonas aeruginosa To be published
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5UE7
| Crystal structure of the phosphomannomutase PMM1 from Candida albicans, apoenzyme state | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Phosphomannomutase | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-12-29 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of the phosphomannomutase PMM1 from Candida albicans, apoenzyme state To Be Published
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5UB8
| Crystal structure of YPT31, a Rab family GTPase from Candida albicans, in complex with GDP and Zn(II) | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Likely rab family GTP-binding protein, ZINC ION | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-12-20 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of YPT31, a Rab family GTPase from Candida albicans, in complex with GDP and Zn(II) To Be Published
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5UF8
| Crystal structure of the ARF family small GTPase ARF2 from Candida albicans in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Potential ADP-ribosylation factor | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-01-03 | 公開日 | 2017-01-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.872 Å) | 主引用文献 | Crystal structure of the ARF family small GTPase ARF2 from Candida albicans in complex with GDP To Be Published
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8U7G
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5UXA
| Crystal structure of macrolide 2'-phosphotransferase MphB from Escherichia coli | 分子名称: | CALCIUM ION, Macrolide 2'-phosphotransferase II | 著者 | Stogios, P.J, Evdokimova, E, Egorova, O, Di Leo, R, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-22 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The evolution of substrate discrimination in macrolide antibiotic resistance enzymes. Nat Commun, 9, 2018
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4XI1
| Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase LubX, GLYCEROL, ... | 著者 | Stogios, P.J, Quaile, T, Skarina, T, Cuff, M, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-01-06 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.983 Å) | 主引用文献 | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
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6U69
| Crystal structure of Yck2 from Candida albicans, apoenzyme | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-08-29 | 公開日 | 2019-10-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol, 27, 2020
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6U6A
| Crystal structure of Yck2 from Candida albicans in complex with kinase inhibitor GW461484A | 分子名称: | 2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine, SULFATE ION, Serine/threonine protein kinase | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Chang, C, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-08-29 | 公開日 | 2019-10-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol, 27, 2020
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7RGN
| Crystal structure of putative fructose-1,6-bisphosphate aldolase from Candida auris | 分子名称: | Fructose-bisphosphate aldolase, GLYCEROL, ISOPROPYL ALCOHOL, ... | 著者 | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-15 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of putative fructose-1,6-bisphosphate aldolase from Candida auris To Be Published
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7RCA
| Crystal structure of Aro2p chorismate synthase from Candida lusitaniae | 分子名称: | CHLORIDE ION, Chorismate synthase, SULFATE ION | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-07-07 | 公開日 | 2021-07-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Crystal structure of Aro2p chorismate synthase from Candida lusitaniae To Be Published
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