4LJD
 
 | | Structure of a photobleached state of IrisFP under low intensity laser-light | | 分子名称: | Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION | | 著者 | Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D. | | 登録日 | 2013-07-04 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
J.Am.Chem.Soc., 135, 2013
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4L6R
 | | Structure of the class B human glucagon G protein coupled receptor | | 分子名称: | DI(HYDROXYETHYL)ETHER, Soluble cytochrome b562 and Glucagon receptor chimera | | 著者 | Siu, F.Y, He, M, de Graaf, C, Han, G.W, Yang, D, Zhang, Z, Zhou, C, Xu, Q, Wacker, D, Joseph, J.S, Liu, W, Lau, J, Cherezov, V, Katritch, V, Wang, M.W, Stevens, R.C, GPCR Network (GPCR) | | 登録日 | 2013-06-12 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the human glucagon class B G-protein-coupled receptor.
Nature, 499, 2013
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1KNW
 | | Crystal structure of diaminopimelate decarboxylase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Diaminopimelate decarboxylase, LITHIUM ION, ... | | 著者 | Levdikov, V, Blagova, L, Bose, N, Momany, C. | | 登録日 | 2001-12-19 | | 公開日 | 2003-11-11 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Diaminopimelate Decarboxylase uses a Versatile Active Site for Stereospecific Decarboxylation
To be Published
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5D10
 | | Kinase domain of cSrc in complex with RL236 | | 分子名称: | N-[4-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}oxy)phenyl]prop-2-enamide, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Becker, C, Mayer-Wrangowski, S.C, Julian, E, Rauh, D. | | 登録日 | 2015-08-03 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.
J.Med.Chem., 58, 2015
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4LEP
 | | Structural insights into substrate recognition in proton dependent oligopeptide transporters | | 分子名称: | N-[(1R)-1-phosphonoethyl]-L-alaninamide, Proton:oligopeptide symporter POT family, ZINC ION | | 著者 | Guettou, F, Quistgaard, E.M, Tresaugues, L, Moberg, P, Jegerschold, C, Zhu, L, Jong, A.J, Nordlund, P, Low, C. | | 登録日 | 2013-06-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into substrate recognition in proton-dependent oligopeptide transporters.
Embo Rep., 14, 2013
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4LLW
 | | Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A | | 分子名称: | SULFATE ION, light chain Clambda, mutated Pertuzumab Fab heavy chain | | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | | 登録日 | 2013-07-09 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
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1KSR
 | | THE REPEATING SEGMENTS OF THE F-ACTIN CROSS-LINKING GELATION FACTOR (ABP-120) HAVE AN IMMUNOGLOBULIN FOLD, NMR, 20 STRUCTURES | | 分子名称: | GELATION FACTOR | | 著者 | Fucini, P, Renner, C, Herberhold, C, Noegel, A.A, Holak, T.A. | | 登録日 | 1997-02-07 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold.
Nat.Struct.Biol., 4, 1997
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4LG6
 | | Crystal structure of ANKRA2-CCDC8 complex | | 分子名称: | Ankyrin repeat family A protein 2, Coiled-coil domain-containing protein 8, UNKNOWN ATOM OR ION | | 著者 | Xu, C, Bian, C, Tempel, W, Mackenzie, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-27 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8.
Structure, 23, 2015
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4LG9
 | | Crystal structure of TBL1XR1 WD40 repeats | | 分子名称: | F-box-like/WD repeat-containing protein TBL1XR1, UNKNOWN ATOM OR ION | | 著者 | Xu, C, Tempel, W, He, H, Wu, X, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-27 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of TBL1XR1 WD40 repeats
TO BE PUBLISHED
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4LJC
 | | Structure of an X-ray-induced photobleached state of IrisFP | | 分子名称: | Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION | | 著者 | Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D. | | 登録日 | 2013-07-04 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
J.Am.Chem.Soc., 135, 2013
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4LLD
 | | Structure of wild-type IgG1 antibody heavy chain constant domain 1 and light chain lambda constant domain (IgG1 CH1:Clambda) at 1.19A | | 分子名称: | Ig gamma-1 chain C region, Ig lambda-2 chain C region | | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | | 登録日 | 2013-07-09 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
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4LLH
 | | Substrate bound outward-open state of the symporter BetP | | 分子名称: | 2-(trimethyl-lambda~5~-arsanyl)ethanol, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, ... | | 著者 | Perez, C, Faust, B, Ziegler, C. | | 登録日 | 2013-07-09 | | 公開日 | 2014-05-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na(+) coupling.
Nat Commun, 5, 2014
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4LLY
 | | Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A | | 分子名称: | GLYCEROL, MAGNESIUM ION, light chain Clambda, ... | | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | | 登録日 | 2013-07-09 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
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4LLQ
 | | Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 2 beta, CRD2b) at 1.42A | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, mutated CH1, mutated light chain Clambda | | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | | 登録日 | 2013-07-09 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
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4LLU
 | | Structure of Pertuzumab Fab with light chain Clambda at 2.16A | | 分子名称: | ACETATE ION, Light chain CLAMBDA, PERTUZUMAB FAB Heavy chain, ... | | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | | 登録日 | 2013-07-09 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
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4LLM
 | | Structure of redesigned IgG1 first constant and lambda domains (CH1:Clambda constant redesign 1, CRD1) at 1.75A | | 分子名称: | Ig gamma-1 chain C region, Ig lambda-2 chain C region | | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | | 登録日 | 2013-07-09 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
Nat.Biotechnol., 32, 2014
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4LG7
 | | Crystal structure MBD4 MBD domain in complex with methylated CpG DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain protein 4, UNKNOWN ATOM OR ION | | 著者 | Xu, C, Tempel, W, Wernimont, A.K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-27 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure MBD4 MBD domain in complex with methylated CpG DNA
To be Published
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2J95
 | | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | | 分子名称: | 5'-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-2,2'-BITHIOPHENE-5-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, ACTIVATED FACTOR XA LIGHT CHAIN, ... | | 著者 | Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P. | | 登録日 | 2006-11-02 | | 公開日 | 2007-03-20 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides.
J.Med.Chem., 50, 2007
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4LJB
 | | Structure of a photobleached state of IrisFP under high intensity laser-light | | 分子名称: | Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION | | 著者 | Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D. | | 登録日 | 2013-07-04 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9019 Å) | | 主引用文献 | Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
J.Am.Chem.Soc., 135, 2013
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1KZX
 | | Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) | | 分子名称: | INTESTINAL FATTY ACID-BINDING PROTEIN (T54) | | 著者 | Zhang, F, Luecke, C, Baier, L.J, Sacchettini, J.C, Hamilton, J.A. | | 登録日 | 2002-02-08 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism
Biochemistry, 42, 2003
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1LHS
 | | LOGGERHEAD SEA TURTLE MYOGLOBIN (AQUO-MET) | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Nardini, M, Tarricone, C, Lania, A, Desideri, A, De Sanctis, G, Coletta, M, Petruzzelli, R, Ascenzi, P, Coda, A, Bolognesi, M. | | 登録日 | 1995-02-01 | | 公開日 | 1995-06-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution.
J.Mol.Biol., 247, 1995
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2J49
 | | Crystal structure of yeast TAF5 N-terminal domain | | 分子名称: | TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 | | 著者 | Romier, C, James, N, Birck, C, Cavarelli, J, Vivares, C, Collart, M.A, Moras, D. | | 登録日 | 2006-08-28 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure, Biochemical and Genetic Characterization of Yeast and E. Cuniculi Taf(II)5 N-Terminal Domain: Implications for TFIID Assembly.
J.Mol.Biol., 368, 2007
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1KZW
 | | Solution structure of Human Intestinal Fatty acid binding protein | | 分子名称: | INTESTINAL FATTY ACID-BINDING PROTEIN (A54) | | 著者 | Zhang, F, Luecke, C, Baier, L.J, Sacchettini, J.C, Hamilton, J.A. | | 登録日 | 2002-02-08 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism
Biochemistry, 42, 2003
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3SJH
 | | Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP-Latrunculin A | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Renault, L, Husson, C, Carlier, M.F, Didry, D. | | 登録日 | 2011-06-21 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly
Embo J., 31, 2012
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4UU7
 | | Crystal structure of zebrafish Sirtuin 5 in complex with 3-methyl- succinylated CPS1-peptide | | 分子名称: | (2R)-2-methylbutanedioic acid, (2S)-2-methylbutanedioic acid, 1,2-ETHANEDIOL, ... | | 著者 | Pannek, M, Gertz, M, Steegborn, C. | | 登録日 | 2014-07-24 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors.
Angew.Chem.Int.Ed.Engl., 53, 2014
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