3SJH

Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP-Latrunculin A

Summary for 3SJH

• Entry DOI: 10.2210/pdb3sjh/pdb
• Descriptor: Actin, alpha skeletal muscle, Ciboulot/Thymosin beta-4 chimeric protein, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: protein-protein complex, contractile protein, protein binding
• Biological source: Drosophila melanogaster; More
• Cellular location: Cytoplasm, cytoskeleton: P68135 P62326
• Total number of polymer chains: 2
• Total formula weight: 48804.33

Authors

Renault, L.,Husson, C.,Carlier, M.F.,Didry, D. (deposition date: 2011-06-21, release date: 2012-01-25, Last modification date: 2023-09-13)

• Primary citation: Didry, D.,Cantrelle, F.X.,Husson, C.,Roblin, P.,Moorthy, A.M.,Perez, J.,Le Clainche, C.,Hertzog, M.,Guittet, E.,Carlier, M.F.,van Heijenoort, C.,Renault, L.; How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly; Embo J., 31:1000-1013, 2012; PubMed: 22193718; DOI: 10.1038/emboj.2011.461

Experimental method

X-RAY DIFFRACTION (1.75 Å)