3SJH
Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP-Latrunculin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Actin, alpha skeletal muscle | polymer | 375 | 41862.6 | 1 | UniProt (P68135) Pfam (PF00022) In PDB | Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits) | Alpha-actin-1 |
| 2 | B | Ciboulot/Thymosin beta-4 chimeric protein | polymer | 54 | 5988.7 | 1 | UniProt (O97428) UniProt (P62326) Pfam (PF01290) In PDB | Drosophila melanogaster | Ciboulot, isoform B, EG:EG0007.11 protein, RE50273p |
| 3 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | A | LATRUNCULIN A | non-polymer | 421.6 | 1 | Chemie (LAR) | |||
| 6 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
B: 8 - 29 (UniProt: O97428)
B: 30 - 56 (UniProt: P62326)
| PDB | External Database | Details |
|---|---|---|
| Gly 3 | - | cloning artifact |
| Pro 4 | - | cloning artifact |
| Leu 5 | - | cloning artifact |
| Gly 6 | - | cloning artifact |
| Ser 7 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47851.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 953.0 | |
| All* | Total formula weight | 48804.3 |
