4ES9
 
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4W1U
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4G0S
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4WPY
 | | Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-II) | | 分子名称: | GLYCEROL, protein DL-Rv1738, trifluoroacetic acid | | 著者 | Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N. | | 登録日 | 2014-10-21 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WVG
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4WVI
 | | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep2). | | 分子名称: | Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, substrate peptide (pep2) | | 著者 | Young, P.G, Ting, Y.T, Baker, E.N. | | 登録日 | 2014-11-05 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
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4WSP
 | | Racemic crystal structure of Rv1738 from Mycobacterium tuberculosis (Form-I) | | 分子名称: | CHLORIDE ION, protein DL-Rv1738 | | 著者 | Bunker, R.D, Mandal, K, Kent, S.B.H, Baker, E.N. | | 登録日 | 2014-10-28 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WVJ
 | | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with an inhibitor peptide (pep3). | | 分子名称: | Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, inhibitor peptide (PEP3) | | 著者 | Young, P.G, Ting, Y.T, Baker, E.N. | | 登録日 | 2014-11-05 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
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4WVH
 | | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep1). | | 分子名称: | Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, substrate peptide (pep1) | | 著者 | Young, P.G, Ting, Y.T, Baker, E.N. | | 登録日 | 2014-11-05 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
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1LCT
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1TY2
 | | Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J) | | 分子名称: | ZINC ION, putative exotoxin (superantigen) | | 著者 | Baker, H.M, Proft, T, Webb, P.D, Arcus, V.L, Fraser, J.D, Baker, E.N. | | 登録日 | 2004-07-07 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization
J.Biol.Chem., 279, 2004
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1TY0
 | | Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J) | | 分子名称: | putative exotoxin (superantigen) | | 著者 | Baker, H.M, Proft, T, Webb, P.D, Arcus, V.L, Fraser, J.D, Baker, E.N. | | 登録日 | 2004-07-06 | | 公開日 | 2004-08-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization
J.Biol.Chem., 279, 2004
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1VEW
 | | MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI | | 分子名称: | HYDROXIDE ION, MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | | 著者 | Edwards, R.A, Baker, H.M, Whittaker, M.M, Whittaker, J.W, Jameson, G.B, Baker, E.N. | | 登録日 | 1998-01-20 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Escherichia coli manganese superoxide dismutase at 2.1-angstrom resolution.
J.Biol.Inorg.Chem., 3, 1998
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1OQG
 | | Crystal structure of the D63E mutant of the N-lobe human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, Baker, E.N. | | 登録日 | 2003-03-09 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin
Biochemistry, 42, 2003
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1QHU
 | | MAMMALIAN BLOOD SERUM HAEMOPEXIN DEGLYCOSYLATED AND IN COMPLEX WITH ITS LIGAND HAEM | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, PROTEIN (HEMOPEXIN), ... | | 著者 | Paoli, M, Baker, H.M, Morgan, W.T, Smith, A, Baker, E.N. | | 登録日 | 1999-05-27 | | 公開日 | 1999-10-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two beta-propeller domains.
Nat.Struct.Biol., 6, 1999
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1QJS
 | | mammalian blood serum haemopexin glycosylated-native protein and in complex with its ligand haem | | 分子名称: | CHLORIDE ION, HEMOPEXIN, PHOSPHATE ION, ... | | 著者 | Paoli, M, Baker, H.M, Morgan, W.T, Smith, A, Baker, E.N. | | 登録日 | 1999-07-01 | | 公開日 | 2000-02-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of Hemopexin Reveals a Novel High-Affinity Heme Site Formed between Two Beta-Propeller Domains.
Nat.Struct.Biol., 6, 1999
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1CB6
 | | STRUCTURE OF HUMAN APOLACTOFERRIN AT 2.0 A RESOLUTION. | | 分子名称: | CHLORIDE ION, Lactotransferrin | | 著者 | Jameson, G.B, Anderson, B.F, Norris, G.E, Thomas, D.H, Baker, E.N. | | 登録日 | 1999-03-01 | | 公開日 | 1999-03-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change.
Acta Crystallogr.,Sect.D, 54, 1998
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6O04
 | | M.tb MenD IntII bound with Inhibitor | | 分子名称: | (1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid, 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ... | | 著者 | Johnston, J.M, Bashiri, G, Bulloch, E.M, Jirgis, E.M.N, Nigon, L.V, Chuang, H, Baker, E.N. | | 登録日 | 2019-02-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
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6O0G
 | | M.tb MenD bound to Intermediate I and Inhibitor | | 分子名称: | 1,4-dihydroxy-2-naphthoic acid, 2-OXOGLUTARIC ACID, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ... | | 著者 | Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Chuang, H, Nigon, L.V, Baker, E.N. | | 登録日 | 2019-02-16 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
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1PGS
 | | THE THREE-DIMENSIONAL STRUCTURE OF PNGASE F, A GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM | | 分子名称: | PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F | | 著者 | Norris, G.E, Stillman, T.J, Anderson, B.F, Baker, E.N. | | 登録日 | 1994-10-06 | | 公開日 | 1995-01-26 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The three-dimensional structure of PNGase F, a glycosylasparaginase from Flavobacterium meningosepticum.
Structure, 2, 1994
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6O0J
 | | M.tb MenD with ThDP and Inhibitor bound | | 分子名称: | 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ACETATE ION, ... | | 著者 | Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Nigon, L.V, Chuang, H, Ho, N.A.T, Baker, E.N. | | 登録日 | 2019-02-16 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
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6O0N
 | | M.tb MenD with Inhibitor | | 分子名称: | 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | | 著者 | Johnston, J.M, Ho, N.A.T, Bashiri, G, Bulloch, E.M, Nigon, L.V, Jirgis, E.M.N, Baker, E.N. | | 登録日 | 2019-02-16 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
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6N0A
 | | Structure of the major pilin protein (T-18.1) from Streptococcus pyogenes serotype MGAS8232 | | 分子名称: | CALCIUM ION, Major pilin backbone protein T-antigen | | 著者 | Young, P.G, Raynes, J.M, Loh, J.M, Proft, T, Baker, E.N, Moreland, N.J. | | 登録日 | 2018-11-06 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Infect.Immun., 87, 2019
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6OVT
 | | Crystal Structure of IlvD from Mycobacterium tuberculosis | | 分子名称: | DI(HYDROXYETHYL)ETHER, Dihydroxy-acid dehydratase, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Almo, S.C, Grove, T.L, Bonanno, J.B, Baker, E.N, Bashiri, G. | | 登録日 | 2019-05-08 | | 公開日 | 2019-08-07 | | 最終更新日 | 2019-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | The active site of theMycobacterium tuberculosisbranched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.
J.Biol.Chem., 294, 2019
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6BBT
 | | Structure of the major pilin protein (T-13) from Streptococcus pyogenes serotype GAS131465 | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Young, P.G, Baker, E.N, Moreland, N.J. | | 登録日 | 2017-10-19 | | 公開日 | 2018-10-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Infect.Immun., 87, 2019
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